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      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  13 upvotes 5 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community Broccoli supplement (Sulforaphane) for better Minox results?

      in Minoxidil  4 upvotes 3 years ago
      Broccoli or sulforaphane supplements are unlikely to improve Minoxidil results due to the need for an unrealistically large dose. Tretinoin, micro-needling, and low-dose oral Minoxidil may be more effective for those lacking the necessary enzyme in the scalp.

      community Fighting Seb Derm + MPB - Winning

      in Progress Pictures  74 upvotes 9 months ago
      The user successfully managed hair regrowth by using a combination of finasteride, dutasteride, minoxidil, and specific shampoos to treat seborrheic dermatitis. They emphasize the importance of maintaining a healthy scalp and are considering food intolerance tests to further address inflammation.

      community Positivity for anyone that's worried about Fin.

       8 upvotes 7 years ago
      A user shared their positive experience with finasteride for hair loss, noting improved hair thickness and some regrowth after a year of use. They also mentioned using peppermint oil, collagen, Nizoral, zinc supplements, and hair and mane shampoo and conditioner.

      community Can’t take fin - options/alts?

      in Finasteride/Dutasteride  6 upvotes 4 years ago
      User seeks non-finasteride hair loss treatments, suggests Eucapil, minoxidil, microneedling, keto shampoo, oral castor oil, and alfatradiol. Reply recommends vitamin D, zinc, pumpkin seed oil, saw palmetto, and high black tea intake, but emphasizes minoxidil and microneedling as most effective.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  122 upvotes 8 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community My Jan-June Hair Transformation

      in Update  567 upvotes 1 year ago
      The conversation is about a user's hair transformation using a routine that included dermastamping, minoxidil, finasteride, ketoconazole, and rosemary oil. The user later stopped using minoxidil and rosemary oil due to greasiness, continuing with finasteride, dermastamping, and ketoconazole.

      community Coconut Oil + Castor Oil Hair Regrowth | YEAR 1.5

       14 upvotes 8 years ago
      The post and conversation discuss using coconut oil and castor oil for hair regrowth over 1.5 years. Some users suggest using finasteride, minoxidil, and RU58841 for better results, while others prefer natural oils to avoid side effects.

      community ultimate nuclear stack? need more suggestions bruhh

      in Technology  2 upvotes 10 months ago
      The conversation discusses an extensive hair loss treatment regimen including dutasteride, GT20029, RU58841, pyrilutamide, minoxidil, microneedling, ketoconazole shampoo, and experimental compounds. The user humorously describes their approach as a comprehensive strategy to combat hair loss while maintaining hair growth.

      community Topical rapamycin, metformin, a-kg grow hair

      in Research/Science  13 upvotes 5 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community How strong is topical spiro? Close to God tier stack.

      in Product  8 upvotes 3 years ago
      Topical spiro's effectiveness on androgens is discussed. User tried oral DUT, oral Min, keto/nizoral, and RU but experienced worsening hair loss and chest pains. Suggestion given to increase dutasteride and oral minoxidil dosage before considering spironolactone.

      community Had sides on finasteride ? A word of hope.

      in Finasteride  26 upvotes 8 years ago
      A user's experience with hair loss treatments, including finasteride and other options such as RU58841, Nizoral, Pumpkin Seed, and Adenosine; the importance of being in a positive frame of mind when considering taking finasteride; and the need to address life issues before starting finasteride.

      community Mixing Stemoxydine 5% with premixed solution of RU58841 5%

      in Research/Science  2 upvotes 2 years ago
      The user is using Dutasteride, Nizoral, and RU58841 for hair loss and is considering mixing RU58841 with Stemoxydine for better scalp coverage but is concerned about the potential degradation of RU58841 when mixed with a water-based solution. They are seeking advice on the feasibility of this mixture.

      community Is this the best current Stack that doesnt involve FIN/DUT?

      in Treatment  7 upvotes 1 year ago
      The post and conversation are about a hair loss treatment stack without finasteride or dutasteride. The suggested treatments include Alfatradiol, Koshine826, Ketoconazole lotion, Minoxidil, microneedling, Tretinoin, and Stemoxydine.

      community Topical Finasteride: Update

      in Finasteride  63 upvotes 7 years ago
      A user applied a homemade topical finasteride solution daily for 35 days, reducing hair shedding significantly with minimal side effects. They plan to continue for 90 days and will provide further updates.

      community Shedding increase from pumpkin seed oil - dread shed or time to stop?

      in Female 5 months ago
      A user experienced increased hair shedding after taking pumpkin seed oil for 4 weeks and is unsure if it's a "dread shed" or if the oil isn't suitable. They cannot tolerate anti-androgens like spironolactone and finasteride due to side effects and are seeking advice on whether to continue with pumpkin seed oil.

      community Mechanism of Action these drugs re-grow hair?

      in Technology  2 upvotes 2 years ago
      Minoxidil, finasteride, and RU58841 promote hair growth by different mechanisms, with minoxidil and prostaglandin E1 being specifically mentioned. Corticosteroids can also cause hair growth.

      community Which compounds in Saw Palmetto are actually beneficial?

      in Research/Science  3 upvotes 1 year ago
      Saw palmetto's fatty acids, particularly lauric and linoleic acids, inhibit enzymes linked to hair loss, while sterols like beta-sitosterol are less effective due to poor absorption. The conversation questions which specific compounds in saw palmetto contribute to its anti-androgenic effects.

      community Looking for Latanoprost sources EU

      in Product  2 upvotes 2 years ago
      The user has been using MinoxidilMax Latanoprost 0.01% and noticed an increase in hair density after years of stability on finasteride and minoxidil. They are seeking help to find a higher dosage of Latanoprost or a reliable source to purchase the powder to make their own, without a prescription or high cost.

      community Is there any new drug that looks promising ?

      in Research/Science  26 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.