Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.
A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.
A user is seeking affordable hair vitamins without biotin, already taking zinc and D3+K2, and has been dealing with chronic telogen effluvium since 2013. They previously used Nutrafol Vegan but found it too expensive.
Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.
A 25-year-old man discusses his struggles with his mother's opposition to his use of Finasteride for hair loss treatment, despite it improving his condition and self-control after a hair transplant. He expresses frustration over her blaming the medication for various issues and the stress caused by her insistence to stop taking it.
The conversation discusses natural DHT blockers like rice bran oil, which may reduce 5α-reductase activity similarly to Minoxidil and Dutasteride. One user argues that finasteride is more reliable and effective than natural alternatives.
A 39-year-old shared a 17-month hair loss treatment update using Dutasteride, Minoxidil, Nizoral shampoo, and a 1.5mm derma roller, noticing significant results after 9-12 months. They also maintain a healthy lifestyle and manage side effects like dry skin with moisturizer.
A user is experiencing renewed hair loss despite using minoxidil and finasteride for two years and is considering options like dutasteride, increasing finasteride dosage, or starting microneedling. Respondents suggest waiting another month before making changes, consulting a dermatologist, and potentially adjusting the treatment regimen.
A user is experiencing worsening hair loss despite using 8mg of oral finasteride and is considering trying minoxidil or redoing blood work. They are concerned about thinning hair on the sides and back of their head.
SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.
A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.
The user is considering resuming finasteride after a 6-month break and is debating the necessity of extensive blood work, including hormone and health markers, to establish a baseline. They are unsure if the tests are necessary since they experienced no side effects previously.
A 21-year-old shared their one-year hair loss treatment journey, using finasteride, a multivitamin, cold water hair washes, peppermint and jojoba oil, zinc, iron, L-arginine, vitamin D, and ashwagandha. They advise seeing a doctor for finasteride, considering lifestyle changes before minoxidil, getting blood work, talking about the issue with friends, and sticking to a treatment plan for at least six months.
Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.
The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.
User experienced hair loss on the top of the head for 2 years, noticed improvement after adding a smoothie with various fruits, vegetables, and seeds to their diet. They observed increased hair growth after 2 weeks of this dietary change.
User experienced significant hair regrowth after 7 months of using 0.5mg finasteride, along with minoxidil and dermastamp. Side effects include increased sensitivity to poor lifestyle choices, but overall confidence improved.
Pumpkin seed oil is discussed as a potential treatment for hair loss, but the study cited is criticized for using a product with multiple ingredients, making it unclear if pumpkin seed oil is effective. The conversation concludes with skepticism about the study's validity and mentions that pumpkin seeds might help with DHT blocking.
GT20029 is a new hair loss treatment in Phase 3 trials in China, using PROTAC technology to target androgen receptors, potentially with fewer side effects than finasteride and minoxidil. VDPHL01, a second-generation minoxidil, is also mentioned as potentially more effective.
PP405 is a promising new treatment for hair loss that activates dormant stem cells in hair follicles, potentially bypassing the effects of DHT. It is currently in phase 2 trials and could be available between 2027 and 2030, but it is not considered a definitive cure.
AI advancements, like AlphaFold, are speeding up drug discovery for hair loss, promising more effective treatments. Current options like minoxidil and finasteride have limitations, but new developments could improve solutions in 5-10 years.
The conversation discusses hair regrowth using Finasteride, Alpecin shampoo, vitamins, RCP serums, and Redensyl, with noticeable improvement in the fifth month. The user experienced some shedding initially but found stability without using Minoxidil, as advised by their dermatologist.
The user experienced significant hair regrowth after one year of using finasteride, minoxidil, and Nizoral shampoo, with no side effects reported. They noted improved social interactions and emphasized the importance of consistency in treatment.
The user experienced improved hair density and thickness after using finasteride and dermarolling for 2.5 years but noticed hair loss when doing anaerobic exercise. They increased their finasteride dose and continued dermarolling but are considering not starting minoxidil due to its perceived hassle and uncertain long-term benefits.
The conversation is about the role of vitamin deficiencies in hair loss and the effectiveness of treatments like Minoxidil, finasteride, and RU58841. It concludes that while vitamins and nutrition are important, they are not the primary solution for androgenic alopecia.
The conversation discusses a person's hair loss treatment over 1.1 years with finasteride, 1.5 years with minoxidil, and 2 months of microneedling, noting less shedding since starting vitamin D3 a month ago. Commenters are impressed with the results.
A person noticed hair thinning, changed their diet, and added collagen and vitamins to see if it would improve hair growth before starting finasteride and considering a hair transplant. Commenters suggest the appearance of hair regrowth may be due to the way the hair is combed rather than actual growth.
Jericho1017 shared their hair regrowth results after nearly 3 years using 1mg finasteride and 10,000mcg biotin daily, with noticeable improvement after 1.5 years and no significant side effects except for watery semen. Some users suggested adding minoxidil and microneedling to improve results, but Jericho1017 is currently content with their progress and not looking to add more treatments.
Minoxidil can cause dark circles and skin issues, and users suggest reducing dosage or switching to foam. Supplements like vitamin C, glycine, and MSM may help with collagen production to reduce these side effects.