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      community Will pp405 have to be inserted rectally for full benefits?

      in Transgender  31 upvotes 6 months ago
      Pp405 is discussed as a potential hair loss treatment, with humorous suggestions about rectal administration for increased effectiveness. Users joke about unconventional methods and express willingness to try anything for hair regrowth.

      community Is PP405 formula available in grey market?

      in Treatment  16 upvotes 1 year ago
      The conversation is about the availability of the PP405 formula for hair loss treatment, with mentions of finasteride and its side effects. Users discuss the potential of obtaining the formula through unofficial channels and the challenges related to its genetic sequence and delivery method.

      community Self-Experiment - Topical Rapamycin or a-KB

      in Treatment  4 upvotes 4 years ago
      A user plans to create a DIY topical treatment for hair loss using Rapamycin, possibly combined with alpha-ketoglutaric acid (a-KG). They discuss the concentration and formulation process for Rapamycin, considering safety and skin penetration, and intend to apply it every other day to the scalp.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 4 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community Need help with RU58841 (preparation + dosage).

      in Treatment  3 upvotes 11 months ago
      The conversation is about using RU58841 for hair loss treatment, specifically mixing it with minoxidil without propylene glycol due to an allergy. The user is considering starting with a lower concentration of RU58841 and making smaller batches to maintain efficacy.

      community Compounding for topical formulations?

      in Treatment  1 upvotes 2 years ago
      The post discusses the high cost of a topical hair loss treatment from Happy Head, which contains finasteride, minoxidil, retinoic acid, and hydrocortisone. The user is seeking cheaper alternatives, specifically asking if there are compounding pharmacies that can recreate the same or similar formulation.

      community Ru58841 20mg….making my own solution

      in Treatment  1 upvotes 1 year ago
      The conversation is about making a 20mg/ml RU58841 solution for hair loss treatment using ethanol and propylene glycol. The user receives advice on calculating the correct amount of RU58841 powder needed.

      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      in Research/Science 2 months ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

      in Research/Science  5 upvotes 2 months ago
      AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

      community 1 year Fin/2 months GHK-CU update

      in Update  128 upvotes 3 weeks ago
      The user has been using oral finasteride for over a year and recently added GHK-CU for two months, seeing progress but seeking further improvement, especially on the hairline. They discuss sourcing GHK-CU, its effects, and the importance of third-party testing, while considering additional treatments like dutasteride and hair transplants for better results.

      community The fully haired elites are suppressing the hair loss cure.

      in Satire  363 upvotes 1 month ago
      The conversation humorously suggests that elites with full hair are suppressing a hair loss cure to maintain their dating advantage. It mentions treatments like hair systems, hair transplants, and medications such as Minoxidil and finasteride.

      community Massive Shed at 9/10 Months In

      in Progress Pictures  130 upvotes 1 month ago
      The conversation discusses hair shedding experienced by users undergoing hair loss treatments, including finasteride, minoxidil, and microneedling. Many users report experiencing significant shedding around the 8-12 month mark, which is considered a normal part of the hair regrowth process, with expectations of stronger regrowth following the shedding phase.

      community The best hair restoration is the kind nobody notices

      in Chat  1195 upvotes 1 month ago
      Matthew McConaughey's hair restoration methods are speculated to involve hair systems, transplants, and treatments like finasteride and minoxidil. Many believe he falsely credits his hair regrowth to Regenix, while others suggest he uses a combination of treatments for a natural look.

      community Can this be salvaged with a second transplant?

      in Transplants  22 upvotes 1 month ago
      The user is considering a second hair transplant after previous treatments with finasteride and minoxidil failed to stop hair loss. Suggestions include trying dutasteride, oral minoxidil, scalp micropigmentation, or shaving the head.

      community Doctor didn't prescribe finasteride

      in Finasteride/Dutasteride  3 upvotes 1 month ago
      The user is struggling to obtain a finasteride prescription in France after moving there, despite previously using it alongside minoxidil, kz shampoo, and biotin supplements. They are advised to seek alternative doctors, consider telemedicine platforms, or explore topical finasteride options.

      community Roughly 1.5 years of treatment, don't give up!

      in Progress Pictures  503 upvotes 2 months ago
      The user shared their hair regrowth journey using finasteride, oral minoxidil, and dutasteride over 1.5 years, showing significant improvement. They experienced no side effects and noted increased body hair growth with oral minoxidil.

      community My 5 year hair loss journey on Min & Fin.

      in Progress Pictures  1220 upvotes 2 months ago
      A user shared their 5-year experience using minoxidil and finasteride, noting significant hair improvements without side effects. Consistency, a positive mindset, and lifestyle changes like a healthier diet and better sleep were key to their success.

      community Is there any progress? (2 months)

      in Is this regrowth?  8 upvotes 2 months ago
      The conversation is about a user seeking feedback on hair regrowth progress after two months of using finasteride, minoxidil, ketoconazole shampoo, dermastamping, and iron supplements. Most responses suggest that two months is too early to see significant results and recommend patience, with noticeable changes typically occurring around 4-6 months.

      community Hair regrowth attempt. Age 33 after 10 years bald.

      in Progress Pictures  643 upvotes 3 months ago
      A 33-year-old attempted hair regrowth after 10 years of baldness using topical finasteride, minoxidil, micro-needling, a laser cap, and later oral dutasteride. They noticed some regrowth, especially vellus hairs, and are considering a hair transplant or other treatments despite side effects.

      community Nearly Two Years of Min/Fin — 25M

      in Progress Pictures  124 upvotes 3 months ago
      The user has been using minoxidil and finasteride for nearly two years, seeing some prevention of further hair loss and possible regrowth. Many suggest trying dutasteride or considering a hair transplant as the next step.