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      community Can Pyrilutamide use stopp Minoxidil gains

      in Chat  3 upvotes 2 years ago
      The conversation discusses whether using pyrilutamide would interfere with minoxidil's ability to regrow hair, considering pyrilutamide is seen as a maintenance drug that stops shedding, while minoxidil promotes hair growth but causes initial shedding.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community PP405 (Everychem 3HP) Users, share your story!

      in Chat  18 upvotes 3 days ago
      Everychem's solution, similar to PP405, has mixed results for hair regrowth, with some users reporting improvements and others seeing no change or worsening hair loss. Users are sharing experiences and updates to determine its effectiveness.

      community Severe Panic Attacks on 1mg Fin: Alternative Options?

      in General  56 upvotes 6 months ago
      The user experienced severe side effects from finasteride, including panic attacks and suicidal thoughts, and is seeking alternative hair loss treatments. They have been using oral finasteride and topical minoxidil.

      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  41 upvotes 8 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community mbp alopecia areata or vitamin deficiency

      in Chat 1 year ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

      community Black market pp405? Title title

      in Treatment  8 upvotes 2 months ago
      PP405 is likely fake, and JXL069 is an unrefined prototype with unknown side effects. It's advised to wait for the official PP405 release.

      community 1 month of progress on Fin, Min, and Microneedling

      in Is this regrowth?  63 upvotes 8 months ago
      The user has been using finasteride, minoxidil, and microneedling consistently for one month to improve hair regrowth. They also use collagen peptides, pumpkin seed oil, vitamin D, biotin, nizoral shampoo, adenosine shampoo, caffeine topical, and rosemary oil as part of their routine.

      community Pyrilutamide update: three months

      in Update  31 upvotes 3 years ago
      A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

      community Thoughts on the future of pp405?

      in Research/Science  42 upvotes 4 months ago
      PP405 is considered a promising hair loss treatment, potentially replacing minoxidil but not finasteride. Users are hopeful for future treatments like GT20029 and VDPHL01, while remaining cautious about effectiveness and side effects.

      community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

      in Progress Pictures  83 upvotes 3 years ago
      Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

      community Am I losing my mind or should I be concerned

      in General  144 upvotes 10 months ago
      The user switched from topical to oral finasteride and minoxidil for hair loss and experienced swelling and sensitivity in the left chest area. They are concerned about these symptoms but noticed improvement after skipping a dose.

      community 9 months on fin/min/microneedling

      in Progress Pictures  107 upvotes 1 year ago
      A 22-year-old male experienced hair regrowth and improved hair health after using Minoxidil, Finasteride, and microneedling for nine months, with initial shedding but no significant side effects. Users discussed similar experiences with hair styling difficulties and shared tips for managing hair texture and side effects.
      Help me interpret my bloods

      community Help me interpret my bloods

      in General  65 upvotes 10 months ago
      The user is concerned about high prolactin levels and low testosterone levels after stopping finasteride for three weeks. They are considering resuming finasteride but are worried it might further increase prolactin levels.

      community Pyrilutamide release in Europe?

      in Treatment  2 upvotes 2 years ago
      User asks about Pyrilutamide release in Europe, specifically Germany, and considers importing it from China. No specific treatments mentioned.

      community Scalp MicroPigmentation Results

      in Microneedling  4 upvotes 6 years ago
      A user shared their positive experience with scalp micropigmentation (SMP) to cover hair thinning and a scar, choosing it over hair transplants due to its non-invasive nature and realistic results. They recommend SMP for those struggling with hair loss, emphasizing the importance of finding a trusted artist.

      community Possibility of updates or more information on the pp405

      in Chat  19 upvotes 5 months ago
      The conversation discusses the potential updates on the pp405 trial for hair loss, with completion expected by December 2025. Participants express skepticism about new treatments, suggesting continued use of finasteride, while others hope for innovative solutions beyond current medications.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  12 upvotes 2 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community Why does MPB only affect the scalp

      in Research/Science  14 upvotes 1 year ago
      Male pattern baldness (MPB) may be influenced by androgen receptors in scalp hair follicles and potentially poor blood flow. Transplanted hair is not immune to DHT, and factors like inflammation and scalp tension might also contribute to hair loss.

      community Wimpole Clinic 1850 grafts (23yo) Dr Malkani

      in Progress Pictures  123 upvotes 1 year ago
      A user shared their positive experience with a hair transplant at Wimpole Clinic, performed by Dr. Malkani, and discussed using finasteride at a reduced dose due to side effects. They also mentioned avoiding minoxidil due to heart pain and taking supplements like biotin, marine collagen, viviscal, and krill oil.