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Finasteride and dutasteride can stop hair loss and improve skin, with some users experiencing increased libido and harder erections. However, some report side effects like softer erections and brain fog.

Hope Medicine's HMI-115 is expected to be released in 2027, with phase 3 trials currently recruiting. Concerns include the safety of targeting prolactin and the potential cost of the treatment.

The conversation discusses the user's experience with depression after starting Dutasteride for hair loss, considering whether to lower the dose or try supplements like nootropics. Another user suggests that stopping Dutasteride might not resolve the depression and warns against attributing all issues to the medication.

The user's consideration of taking finasteride as a short-term treatment, while awaiting advances in medical technology such as Pyrilutamide and GT20029; other users' experiences with Finasteride, including potential side effects.

A user expressed disappointment that their hair loss worsened after 11 months using topical finasteride with TrichoSol, despite no side effects and initial signs of improvement. They asked for advice and opinions on their treatment and alternatives, with suggestions including switching to oral finasteride or dutasteride, starting minoxidil, and addressing their seborrheic dermatitis with different shampoos or medical advice.

RCH-01's progress is uncertain, and there's skepticism about its effectiveness. Users are losing hope in this treatment.

Hair loss can be distressing, but treatments like finasteride, minoxidil, and scalp micropigmentation can help manage it. Embrace self-improvement, focus on personal goals, and maintain a positive attitude despite hair loss challenges.

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

A user discusses their positive experience with finasteride, criticizing others for spreading fear about side effects. They emphasize that side effects are often temporary and not as common as some suggest.

BigLu2012 tried various hair loss treatments for 3 years, including Fin, Min, and RU, but experienced side effects and worsening hair condition. Ready-Character1581 suggested focusing on mental health and not stressing about hair, as it looks better than most.

A 24-year-old is struggling with severe depression and anxiety due to hair loss, despite using dutasteride and oral minoxidil for two years. They are advised to consider shaving their head, exploring wigs or hair systems, and focusing on other aspects of life like health, relationships, and career.

The conversation revolves around the psychological impact of hair loss and various treatments. Participants discuss using Minoxidil (Min) and Finasteride (Fin), hair transplants, and therapy for mental health. Some also recommend immediate action at the first signs of hair loss and joining supportive communities.

The user reported high estradiol levels after one month of using finasteride for hair loss. They discussed potential side effects and adjustments to their treatment plan.

The emotional impact of hair loss and the risks associated with common treatments such as finasteride, dutasteride, minoxidil, RU58841, and Fluridil. People discussed their personal experiences with these treatments, including potential side effects and lowered fertility. Hair transplants were also mentioned as a possible solution.

The user experienced significant hair regrowth using finasteride, dutasteride, and oral minoxidil, noting improvements in eyebrows and eyelashes as well. Despite challenges, including a divorce and mental health struggles, the user is grateful for the progress and support from the community.

A user expressed frustration with hair loss treatments, including finasteride, minoxidil with micro-needling, and RU58841, which all failed to stop hair thinning and miniaturization. Suggestions from others included accepting baldness, considering hair systems, and continuing prescribed antidepressants for depression.

Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.

The conversation discusses the impact of hair loss treatments like dutasteride and finasteride, with some users expressing skepticism about media claims linking these drugs to severe side effects like suicidal ideation. Many participants criticize the media, particularly British tabloids, for fearmongering and emphasize the psychological impact of hair loss itself.

A 30-year-old shared positive results after 6 months of using 1mg oral finasteride daily for hair loss, without minoxidil. Hair loss stopped around month 2, and noticeable regrowth began around month 4.5, with no side effects reported.

The user has been using finasteride for 3 months and minoxidil for over 4 years to treat hair loss, experiencing initial anxiety and a possible nocebo effect but now reports no significant side effects. They also tried micro-needling briefly but stopped, and other users have mixed reactions to their results.

A 26-year-old male started minoxidil treatment for male-pattern baldness and saw significant regrowth in three months. He is considering finasteride but is hesitant due to potential side effects.

The user experienced aggressive hair loss despite using oral finasteride and minoxidil, with additional issues like dandruff and eyebrow hair loss. They are considering switching to oral minoxidil and dutasteride due to scalp inflammation and lack of improvement.

The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.

Some users experience worsening hair loss with dutasteride and improvement after switching back to finasteride, while others find better results with dutasteride. The effectiveness of treatments like finasteride, dutasteride, minoxidil, and RU58841 varies, requiring individuals to try different combinations or dosages to find what works best.

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

The user experienced positive hair growth with finasteride but developed gut issues, dry skin, thinning eyebrows, fatigue, low libido, and erection difficulties after stopping it. They are seeking advice on whether to resume finasteride or stay off it to recover.

The user experienced severe side effects from oral finasteride, including sexual dysfunction and mental health issues, and switched to topical finasteride, which led to significant hair shedding. They are considering other treatments like RU58841 or topical dutasteride and are advised to check testosterone levels and address potential underlying health issues.

HMI-115 shows promising hair growth and thickening in just 2 months. Results are positive but need more time for confirmation.