The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
The user experienced hair improvement after six months of using 1mg oral finasteride, with some side effects like reduced libido and initial mood changes. They are considering adding oral minoxidil for further regrowth.
A 28-year-old male noticed hair thinning and is considering treatments like minoxidil and finasteride but is concerned about finasteride's potential effects on epilepsy. He has tried microneedling, tretinoin, and minoxidil with slight improvement.
Switching from finasteride to dutasteride improved erections, sex drive, and mood for one user, though experiences vary widely. Some users report fewer side effects with dutasteride, while others experience more severe issues or hair loss.
The user is stressed about hair loss and is using a HIMS topical treatment containing finasteride, ketoconazole, minoxidil, and biotin, but is concerned about the oily appearance it causes. They are considering switching to Rogaine (minoxidil) due to budget constraints and side effect concerns with oral finasteride.
The user has androgenetic alopecia (AGA) and low Vitamin D levels, and they started using topical minoxidil (5%). They are considering finasteride but are concerned about side effects and are advised to seek mental health support.
Finasteride is used for hair stabilization, while minoxidil is avoided due to side effects. Styling tips include using hair fibers, washing hair less frequently, and managing anxiety related to appearance.
A user's hair loss treatment progress over the last 6 months using finasteride, minoxidil and dermarolling; other users have commented to ask questions or share their own experiences.
The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.
The conversation discusses using topical liposomal finasteride for hair loss, with concerns about high DHT levels. The user's DHT level is above the normal range, which may affect hair health.
Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.
A 30-year-old man shared his experience with finasteride, taking 1mg every other day, which led to sexual side effects and other issues, prompting him to stop the treatment despite initial hair improvement. He previously tried natural methods and minoxidil without much success and is now considering a buzzcut.
A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.
RU58841 cured seborrheic dermatitis, oily scalp, dandruff, and scalp pain, improving hair health when combined with Minoxidil. Another user noted diet impacts their seborrheic dermatitis and that finasteride hasn't changed their condition.
User made progress with hair loss using Fin, Min, and microneedling. Experienced side effects like improved skin, brain fog, and memory issues, but adjusting Fin dosage helped.
A user's decision to shave their head after experiencing hair loss since the age of 17, and discussion around the potential use of Fin for treating hair loss.
A person with hair loss due to seborrheic dermatitis saw improvement after treating the condition and using 5mg oral minoxidil, topical minoxidil, collagen, biotin, and vitamins. They are asking if the progress is real, and others have noted the oral minoxidil as a significant treatment.
The conversation humorously discusses the effects of finasteride on sexual orientation and hair improvement, with users joking about its potential to change attraction. It also mentions other treatments like dutasteride and minoxidil, with some users sharing their experiences and side effects.
A user shared their experience with hair loss treatments, including finasteride, topical finasteride, derma rolling, melaleuca oil, caffeine powder, topical vitamin D, keto shampoo, and revive shampoo. They also changed their diet to address psoriasis and leaky gut.
A user's experience with using 5AR inhibitors (Finasteride and Dutasteride) in combination with Minoxidil foam and microneedling, which resulted in substantial improvements to their crown density and hairline, despite high systemic levels of testosterone and dihydrotestosterone.
The post and conversation are about a user's progress with hair loss using oral finasteride and minoxidil foam. The user experienced new hair growth after 6-8 months and had to shave their head a few times, but continued taking the treatments and is happy with the results.
Stopping finasteride due to side effects and family planning can lead to temporary increased hair shedding, which may stabilize over time. Consider topical treatments or a lower dose after addressing current concerns.
A 15-year-old experiencing hair loss and anxiety is using minoxidil and microneedling but is advised against starting finasteride or dutasteride due to age. The discussion emphasizes consulting a doctor, considering hormonal evaluations, and exploring non-medication coping strategies.
The user stopped finasteride for family planning but plans to restart it and is considering dutasteride. Users discuss the safety of finasteride during family planning, with some sharing experiences of having healthy children while on the medication.
A 15% discount is offered on hair research products like RU58841 and TEMPOL at Chemyo.com. The legality of selling these compounds is confirmed by the seller.
The conversation discusses hair cloning progress and mentions treatments like Minoxidil, finasteride, and RU58841. Users also talk about hair transplants and their effectiveness.
The conversation is about a person considering participating in a study for Clascoterone, a topical cream for hair loss, and seeking advice on potential side effects. They have mild hair loss and are not currently using other treatments like finasteride.