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      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community What’s the most ridiculous theory you’ve seen on the cause of MPB?

      in Chat  45 upvotes 4 months ago
      The conversation discusses various absurd theories about the causes of male pattern baldness, with some users suggesting treatments like oral dutasteride. It highlights misinformation and humorous myths, such as hair loss being linked to testosterone levels or masturbation.
      Time for change or just in my head?

      community Time for change or just in my head?

      in General  128 upvotes 1 year ago
      A 20-year-old is experiencing hair thinning despite using minoxidil inconsistently for 1.5 years and is considering adding finasteride due to concerns about side effects. They are unsure whether to increase minoxidil application, start finasteride, or if the hair loss is exaggerated in their perception.

      community I feel like people here shrug off nutritional issues too quickly. Particularly for Retrograde Alopecia.

      in Chat  10 upvotes 3 years ago
      The user believes Retrograde Alopecia may be linked to vitamin imbalances, specifically from taking too much Vitamin E, A, Zinc, and Selenium, and suggests it could be a middle ground between Androgenic Alopecia and Telogen Effluvium. Treatments for hair loss mentioned include Androgen inhibitors and improving lifestyle factors like nutrition and sleep, with topical melatonin also recommended for Retrograde Alopecia.

      community I want it all to end so badly. I’ve lost my 20s to this

      in Chat  73 upvotes 3 weeks ago
      A person struggling with hair loss is using treatments like dutasteride, oral minoxidil, and has had a hair transplant but remains deeply unhappy. Others suggest alternative treatments, acceptance, and focusing on other life aspects, emphasizing mental health and therapy.

      community Sensitive to Oral fin + RU. Am I screwed?

      in Product  5 upvotes 4 years ago
      Akinfenrawr experienced negative side effects from oral finasteride and RU58841, and is seeking alternative hair loss treatments. They discuss various options, including raloxifene, oral dutasteride, liposomal finasteride, Breezula, Pyrilutamide, SM04554, and sulforaphane, but have concerns about efficacy, availability, and cost.

      community Experiencing Severe Shedding on Finasteride and Minoxidil After 18 Months

      in Basic Questions  159 upvotes 2 months ago
      The user has been on finasteride for 18 months and experienced significant hair shedding after increasing minoxidil dosage, which has not stopped despite reducing the dosage. They are concerned about the effectiveness of finasteride and whether minoxidil triggered ongoing hair loss, compounded by personal stress and trauma.
      M30. thoughts onswitching from oral to topical

      community M30. thoughts onswitching from oral to topical

      in General  67 upvotes 6 months ago
      A user is considering switching from oral to topical treatments for hair loss due to side effects like watery semen and erectile dysfunction. They are currently using oral finasteride and minoxidil and are concerned about potential sexual side effects with topical use.

      community Accepting the fact that i cant stop it.

      in Chat  64 upvotes 1 year ago
      A user shares their struggle with hair loss despite trying treatments like finasteride, minoxidil, and dutasteride, and expresses frustration over ineffective medical advice and a failed hair transplant. Others in the conversation suggest alternative treatments, acceptance of baldness, and focusing on other life aspects.

      community 26/F - Lots of stuff going on - Pics inside.

       5 upvotes 11 years ago
      A 26 year old female with PCOS who has been dealing with hair loss for several years, despite managing her hormones and taking vitamins. She has tried various treatments such as Nizoral, Minoxidil, Pyrithione zinc, coal tar and salicylic acid to no avail. The user is looking for advice on what else they can do to stop their hair loss.

      community PP405 is nothing but a scam and Pelage know it.

      in Chat  78 upvotes 9 months ago
      PP405 is criticized for overhyped claims and cherry-picked data, with doubts about its effectiveness compared to minoxidil and finasteride. Many users express skepticism, emphasizing the need for more comprehensive trial results.

      community Gyno & testoterone level

      in Finasteride  282 upvotes 2 years ago
      Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

      community Why creatine and gym cause MPD

      in Finasteride/Dutasteride 3 years ago
      Gym and creatine can cause hair loss by increasing testosterone and androgenic activity. DHT blockers may help some, while others need androgen suppression with topical AA like RU or Pyri.

      community Losing my hair since 18, feel like a monster

      in Chat  36 upvotes 3 months ago
      A 21-year-old is experiencing severe hair loss despite using finasteride and minoxidil, and plans to try dutasteride. Others share similar struggles and suggest various treatments like RU58841, spironolactone, and hair systems, while emphasizing the emotional impact of hair loss.

      community Slowly losing hope, not sure what to think

      in Advice  17 upvotes 7 years ago
      User is experiencing hair loss despite using Minoxidil, finasteride, RU58841, dermarolling, and supplements like fish oil, collagen, hyaluronic acid, and biotin for over a year. They feel mentally distressed as their hair isn't growing longer and they avoid barbers and hats to hide thinning.

      community Adrogens and Covid-19

      in Treatment  7 upvotes 5 years ago
      The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

      community Why balding gets worse in every generation?

      in Chat  81 upvotes 1 year ago
      Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.