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      community PP405 (Everychem 3HP) Users, share your story!

      in Chat  34 upvotes 1 week ago
      Everychem's solution, similar to PP405, has mixed results for hair regrowth, with some users reporting improvements and others seeing no change or worsening hair loss. Users are sharing experiences and updates to determine its effectiveness.

      community 2.5 mg/ED dut and 1% pyrilutamide, still getting itch?

      in Update  1 upvotes 1 year ago
      The user switched from finasteride to 2.5 mg dutasteride daily and added 1% pyrilutamide to address persistent scalp itch, but the itch remains. They also use 2% ketoconazole and 2.5% selenium sulfide shampoo for temporary relief.

      community Track hairline of Pelage executives

      in Research/Science  37 upvotes 6 months ago
      Pelage executives' hairlines were discussed, with speculation about them using PP405 for hair regrowth. Concerns were raised about using untested drugs, with some suggesting executives might not risk using them without safety data.

      community PP405 Hairloss Reversal and Hairline Restoration

      in Treatment  5 upvotes 2 months ago
      PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.

      community Pyrilutamide 3 weeks update once a day

      in Progress Pictures  33 upvotes 2 years ago
      User shared 3-week progress using Pyrilutamide once a day for hair loss. Another user shared their 3-month progress with 0.25% concentration Pyrilutamide, experiencing rollback of 4 years in 3 months.

      community Am I missing something with pp405?

      in Research/Science  32 upvotes 1 year ago
      PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community Pyrilutamide US Phase 2 Trial?

      in Research/Science  27 upvotes 3 years ago
      The Phase 2 trial for Pyrilutamide in the US, which started a year after the China trials, and inquiring about any available information on when it will finish. Treatments discussed include Minoxidil, Finasteride, and RU58841.

      community Is pp405 actually the cure ? Just how exciting is it ?

      in Research/Science  34 upvotes 4 months ago
      PP405 is a promising hair growth stimulant but not a cure for advanced hair loss, as it may only help dormant follicles. Treatments like Minoxidil, Finasteride, and Dutasteride are discussed, with emphasis on early intervention for effectiveness.

      community Sooo whens the next big thing gonna come?

      in Chat  20 upvotes 2 weeks ago
      New hair loss treatments like VDPHL01, PP405, Gt20029, and Breezula are anticipated, with VDPHL01 possibly releasing in 2027/28. Current treatments include finasteride, dutasteride, and minoxidil, but new options are eagerly awaited.

      community New article on PP405..........

      in Research/Science  109 upvotes 11 months ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  217 upvotes 10 months ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  5 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community 7 months progression with dut 0.5 and oral min 2,5

      in Is this regrowth?  49 upvotes 1 year ago
      The conversation discusses hair regrowth progress using dutasteride 0.5 mg and oral minoxidil 2.5 mg over seven months. Users debate the effectiveness, with some noting slight improvements and others suggesting alternative treatments like finasteride.

      community Pelage Recruiting Now for Phase 2

      in Research/Science  10 upvotes 1 year ago
      Pelage is recruiting for phase 2 trials, showing promise for treating bald regions. The discussion highlights its potential effectiveness based on its mechanism of action.

      community 5mg min 0.5mg dut - temple regrowth but ravaged crown? 28M

      in Progress Pictures  39 upvotes 1 month ago
      A 28-year-old male is experiencing temple regrowth but crown thinning while using 5mg minoxidil and 0.5mg dutasteride. The shedding phase is seen as a positive sign of treatment effectiveness, with expectations of noticeable improvements around 6 to 12 months.

      community 5months using Dut/Min twice daily

      in Is this regrowth?  69 upvotes 4 weeks ago
      A 33-year-old male has been using topical dutasteride and minoxidil twice daily, along with a 0.25 mm derma roller every five days, and is experiencing hair shedding but seeing progress. Some users suspect a hair transplant, while others praise the results.

      community By when would pp405 be available in the grey market?

      in Chat  16 upvotes 3 weeks ago
      PP405 might take 3-4 years to be available, but some claim Everychem offers a similar product, though its effectiveness is debated. Users discuss the risks of using untested grey market products and the potential for adverse effects.

      community DUPA, Non Responders and Connective Tissue Disorders

      in Research/Science  9 upvotes 10 months ago
      A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.