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      community Pelage Announces Positive Results of Phase 2a Trials for PP405

      in Update  300 upvotes 11 months ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

      community COQ10 + PQQ for scalp inflammation??

      in Chat  6 upvotes 1 year ago
      A 32-year-old male with diffuse thinning and seborrheic dermatitis has been using finasteride for 8 months without improvement. He is considering COQ10 + PQQ supplements for scalp inflammation and hair loss.

      community Revalid hair complex against hair thinning?

      in Product  3 upvotes 1 year ago
      A 17-year-old with thinning hair is considering using Revalid, a supplement with ingredients like biotin and zinc, based on parental recommendations. Another user suggests that supplements could help since the hair thinning doesn't seem to be androgenic alopecia.

      community When that rogue Nizoral sud hits the tongue.

      in Ketoconazole  13 upvotes 2 years ago
      The conversation is about the accidental taste of Nizoral shampoo, which contains ketoconazole, during hair washing. Specific hair loss treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community No Luck Getting Rid Of The Itchy Scalp. What Now?

      in Chat  10 upvotes 3 years ago
      A user experienced a burning, itchy scalp and hair thinning despite trying finasteride, steroid cream, antihistamines, various shampoos, and supplements. They seek advice on relieving the itch, hoping it will improve hair health.

      community 4 months on finasteride and 2% ketaconazole shampoo only.

      in Progress Pictures  61 upvotes 1 year ago
      A 29-year-old male shares progress pictures after 4 months using finasteride and 2% ketoconazole shampoo, noting initial shedding but overall improvement. He avoids minoxidil and microneedling, and reports thicker hair in balding areas while maintaining high water intake.

      community Normal amount of hair to shed in the shower?

      in Chat  4 upvotes 2 months ago
      The conversation discusses hair shedding while using finasteride and topical minoxidil, with users sharing their experiences of losing 30-100 hairs daily in the shower. One user considers switching to dutasteride due to consistent shedding.

      community Ultimate Stack without nuking your gender (you'll go broke)

      in Treatment  86 upvotes 1 year ago
      A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

      community rudirect ru58841 seems bunk to me

      in Treatment  6 upvotes 4 weeks ago
      RU58841 from rudirect caused more hair shedding and itch, while anageninc's RU58841 improved the situation. Users are concerned about the quality and authenticity of RU58841 from different suppliers, including those from China.

      community Sebum production even on dutasteride, and its relation to MPB.

      in Finasteride/Dutasteride  6 upvotes 5 months ago
      The conversation discusses managing hair loss and scalp issues, with users sharing experiences using treatments like dutasteride, finasteride, ketoconazole, sulfur soap, and topical anti-androgens. Suggestions include trying sulfur soap, scalp massages, spironolactone, and dietary changes to reduce sebum production and dandruff.

      community DHT Blocker without Selenium and Zinc??

      in Female  6 upvotes 1 year ago
      A female user is seeking a DHT blocker without Selenium or Zinc due to hair breakage and is currently using Saw Palmetto, Nature's Bounty Hair, Skin and Nails, Pumpkin seed oil, Dermastamp, and Pura D'or products. She has tried Minoxidil without success and is considering Finasteride but prefers natural options first.

      community Best all in one supplement for hair health

      in Treatment  14 upvotes 5 years ago
      The conversation is about supplements for hair health. Nutrafol and Viviscal are mentioned, with Nutrafol preferred due to saw palmetto; individual supplements like zinc, vitamin D, iron, B complex, magnesium, and inositol are also discussed.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 8 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

      community Fixing DHT Itch (scalp inflammation) with Aloe Vera gel & more

      in Research/Science  13 upvotes 11 months ago
      Aloe vera gel can help reduce scalp inflammation and "DHT itch" associated with hair loss, particularly in those with androgenic alopecia and seborrheic dermatitis. It's suggested to use aloe vera alongside treatments like finasteride and ketoconazole shampoo to manage symptoms and promote scalp health.

      community SHISEIDO is A Bust...

      in Update  26 upvotes 7 years ago
      Shiseido's hair loss treatment reported only 5% regrowth, disappointing many. Users discussed other treatments like Minoxidil, finasteride, RU58841, and CB-03-01 as potential alternatives.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  114 upvotes 1 year ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community PP405 - hair stem cell stimulation

      in Research/Science  53 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community 3-4 Month Re growth (Updating in 3 months)

      in Progress Pictures  57 upvotes 11 months ago
      The post discusses a hair loss treatment regimen including oral finasteride, topical minoxidil, a rejuvenating scalp serum with caffeine, rosemary, and ginger, topical ketoconazole, saw palmetto, and derma rolling. The user seeks advice for scalp pimples and irritation.

      community Most promising cures for baldness as of May 2026

      in Treatment  56 upvotes 3 weeks ago
      PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.

      community Green tea/ soy Isoflavones supplements for MPB

      in Product  4 upvotes 5 years ago
      Green tea extract and soy isoflavones may help with hair loss by inhibiting DHT and providing additional health benefits. Combining these with finasteride and possibly using nizoral shampoo could enhance effectiveness in managing hair loss.