The conversation is about using natural DHT blockers like sawpalmetto, pumpkin seed oil, and stinging nettle extract for hair loss. Sawpalmetto is noted to potentially halt mild hair loss.
A 24-year-old male experiencing increased hair thinning and shedding recently started using rosemary and castor oil, microneedling, and an anti-dandruff shampoo. He is considering adding SawPalmetto and seeks recommendations for a good shampoo.
The user is considering a hair transplant while currently using minoxidil, sawpalmetto, and pumpkin seed oil. Others suggest using finasteride or dutasteride for better results and to prevent further hair loss.
People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.
The user experienced severe side effects from overdosing on sawpalmetto and is considering starting a low dose of finasteride for hair loss, despite concerns about similar side effects. Most responses advise against using finasteride due to potential risks, suggesting consulting a doctor and addressing underlying health issues first.
A 22-year-old is experiencing hair loss after transitioning from fem HRT to DIY testosterone therapy and is considering using Dutasteride while also taking SawPalmetto. They are concerned about the impact on virilization and proper development.
An 18.5-year-old experiencing rapid hair loss is being treated with sawpalmetto, vitamins, and red light therapy, but these seem ineffective. The consideration of finasteride is discussed, weighing its potential side effects against the emotional impact of early hair loss.
PP405 is suspected to be a scam, with users doubting its legitimacy and effectiveness. Many recommend using proven treatments like finasteride and minoxidil.
PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.
Herbal treatments like pumpkin seed oil, sawpalmetto, and rosemary oil showed little to no effectiveness for hair loss, with some users experiencing negative effects. Regular treatments like finasteride and minoxidil are suggested to be more effective, while vigorous scalp massage and low-level laser therapy (LLLT) might offer some benefits.
Zinc picolinate and sawpalmetto may lower DHT but are less effective than finasteride. Finasteride and minoxidil are preferred treatments, with ketoconazole shampoo as a suggested addition.
The conversation discusses the potential benefits of adding Vitamin B6 (P-5-P) to topical hair loss treatments like RU58841, finasteride, or minoxidil. The user suggests that Vitamin B6 might enhance these treatments by naturally lowering scalp prolactin.
PP405 shows promising results for hair growth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.
PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.
The user is considering starting finasteride for hair loss prevention, expressing concerns about potential side effects like reduced libido and erectile dysfunction. They are currently taking sawpalmetto, vitamin D, zinc, vitamin C, and biotin but are unsure if these will be effective.
PP405 is a topical gel being tested for hair regrowth in adults with androgenetic alopecia. Volunteers aged 18-55 are needed for a 16-week trial in several US locations.
The user has been on finasteride for 16 months and is considering natural remedies like peppermint oil, rosemary oil, sawpalmetto, green tea extract, l-lysine, and oral castor oil to enhance hair growth in addition to finasteride. They are interested in the potential benefits of combining these natural treatments with finasteride to improve hair loss outcomes.
Finasteride, dutasteride, sawpalmetto, caffeine, spironolactone, acetyltetrapeptides, tea tree oil, hydrocortisone, zinc pyrithione, latanoprost, melatonin, marine protein supplements, PRP, microneedling, and valproate are discussed as treatments for hair loss. DHT reduction and inflammation control are key strategies.
PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.
A female user is seeking a DHT blocker without Selenium or Zinc due to hair breakage and is currently using SawPalmetto, Nature's Bounty Hair, Skin and Nails, Pumpkin seed oil, Dermastamp, and Pura D'or products. She has tried Minoxidil without success and is considering Finasteride but prefers natural options first.
GT20029 and PP405 are discussed as potential alternatives or complements to finasteride for hair loss treatment. GT20029 is entering phase 3 trials, while PP405 is seen as promising for regrowing hair and possibly eliminating the need for other treatments.
The user started a new hair loss treatment regimen using topical finasteride and minoxidil, sawpalmetto, sulforaphane, and apple extract supplements, while also trying to quit nicotine and fast food. They later cut out supplements due to cost, continued with topical treatment, and experienced improved hair health but faced issues with low libido.
Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.
The conversation discusses the effectiveness of a "Hair growth complex" pill, with skepticism about its ingredients like sawpalmetto and anagain. Users suggest sawpalmetto may help slightly with DHT-related hair loss, but it's less effective than finasteride or dutasteride.
A user started taking Musely men's bloom hair pill, which contains minoxidil, dutasteride, and vitamins, and noticed a stop in hair shedding after switching from other hair loss treatments like hims and Keeps. They are questioning the effectiveness of the Musely pill due to its lower dosage of active ingredients and are curious about others' experiences with the product.
Minoxidil and finasteride are effective for hair loss, but natural oils like pumpkin seed oil and sawpalmetto are not proven to be effective. Topical finasteride may be an option for those who cannot tolerate oral finasteride.
PP405 shows promise for hair growth with significant results after 4 weeks, but skepticism exists due to its unavailability. Some users are hopeful for its potential, while others express concerns about side effects and market release delays.
A user ordered a compounded medication from Musely containing Dutasteride, Minoxidil, and other vitamins, expressing concerns about its contents and effectiveness. Another user shared their experience with side effects but noted hair regrowth, while adjusting the dosage to reduce symptoms.
P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.