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      community Why is there more skepticism in RU than Pyrilutamide?

      in Chat  12 upvotes 3 years ago
      The conversation is about skepticism towards the hair loss treatments RU58841 and Pyrilutamide, with users discussing the lack of human testing for RU58841 and the ongoing trials for Pyrilutamide. Some users believe RU58841 has more anecdotal success, while others highlight Pyrilutamide's current research progress.

      community 10 day solo pyrilutamide update

      in Chat  11 upvotes 3 years ago
      The user started using pyrilutamide for hair loss on January 24, applying 1ml daily without other treatments, and after 10 days noticed reduced hair shedding and improved hair quality, with plans to continue for at least 6 months. They experienced chest pain initially, which could be related to starting methylphenidate or pyrilutamide, but the pain has since subsided.

      community PP405 mechanism question - looking for discussion

      in Treatment  6 upvotes 2 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community making a clascoterone lotion from powder

      in Technology  2 upvotes 1 year ago
      A user is considering making a 2% clascoterone lotion from powder due to unavailability in their location. They plan to mix clascoterone powder with retinol lotion and use literature to determine the correct dosage.

      community Ru 58841 and essential oils question

      in Treatment  3 upvotes 4 years ago
      The user discusses using essential oils like peppermint, rosemary, tea tree, and lavender to improve hair thickness and seborrheic dermatitis. They plan to add RU58841 to their routine and seek advice on using it alongside the essential oils without interference.

      community minoxidil without propylene glycol?

      in Minoxidil  5 upvotes 1 year ago
      Minoxidil without propylene glycol is sought to avoid dermatitis, with Rogaine foam and Tecflox suggested as alternatives. Users discuss using foam to prevent irritation and suggest heating it for easier application.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  215 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Better then Minoxidil( at least for me and my family)

      in Treatment  42 upvotes 2 years ago
      Capronium Chloride and Trichoxidil are suggested as better alternatives to Minoxidil for hair growth without heart side effects. The Japanese Dermatological Association recommends topical Minoxidil over Capronium Chloride.

      community Mixing topical minoxidil and alfatradiol

      in Treatments  39 upvotes 11 months ago
      Mixing minoxidil and alfatradiol in one bottle may affect their effectiveness due to potential stability issues. It's recommended to apply them separately for full benefits.

      community 7 month progress Min/Fin/Microneedle/Ketoconazole

      in Progress Pictures  11 upvotes 2 years ago
      The user has been treating hair loss for 7 months using a combination of pyrilutamide, a topical mix of finasteride and minoxidil, microneedling, a topical mix of GHK-Cu and minoxidil, ketoconazole shampoo, fish collagen peptides, zinc, and vitamin D3. Another user suggests that continuous small improvements could lead to significant hair regrowth over time.

      community Pp405 full presentation on new topical

      in Product  105 upvotes 2 months ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.

      community Minox and retinol? Does it work better?

      in Product  2 upvotes 1 year ago
      A user has been using minoxidil and finasteride for hair loss for about five years, noticing that while it hasn't improved much, it has slowed hair loss. They recently added topical retinol, which seems to have increased hair growth, possibly by enhancing minoxidil absorption and activity.

      community The Solution for Topical Solutions

      in Product  6 upvotes 7 months ago
      Using roll-on bottles for applying minoxidil and RU58841 improves application efficiency and reduces product waste. Topical treatments are used continuously, except on microneedling days.

      community Ulo 0.005% finasteride, 4 month update; no results

      in Progress Pictures  3 upvotes 1 month ago
      The user applied 0.005% topical finasteride, minoxidil, tretinoin, caffeine, and ketoconazole shampoo for four months but saw no hair regrowth. Some users suggested increasing the finasteride dose or trying alternative treatments like clascoterone, pyrilutamide, or RU58841.

      community Science backed answer only from what you have learnt .

      in Chat  5 upvotes 1 year ago
      Alcohol-based minoxidil absorbs better but can cause irritation; non-alcohol-based is gentler. Topical dutasteride shows promise but needs more research; low-dose oral minoxidil (0.25 mg/day) is effective with fewer side effects. Ingredients like Procapil, Redensyl, caffeine, and Anagain in shampoos have limited evidence; ketoconazole shampoo can help when used 2-3 times a week with other treatments.

      community A Year of 1mg Fin + 2% Keto shampoo 2x a week

      in Progress Pictures  294 upvotes 3 years ago
      A user who has had success with 1 mg of finasteride and 2% keto shampoo used twice weekly, as well as other treatments such as oral minoxidil, spiro, and RU58841 potentially being considered in the future for further hair growth.