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      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Ru58841 completely got rid of my seb derm

      in Chat  7 upvotes 2 years ago
      RU58841 cured seborrheic dermatitis, oily scalp, dandruff, and scalp pain, improving hair health when combined with Minoxidil. Another user noted diet impacts their seborrheic dermatitis and that finasteride hasn't changed their condition.

      community PP405 2a study was a safety study. Some rational explaining.

      in Research/Science  22 upvotes 9 months ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community 3yr Fin/Dut/Niz NW3+ —> NW1.5 Pictures with Writeup

      in Progress Pictures  32 upvotes 5 years ago
      A user improved their hair loss from NW3+ to NW1.5 over three years using a regimen of dutasteride, finasteride, Nizoral, biotin, and collagen. They experienced some side effects and adjusted dosages over time, and noted additional benefits like better skin and muscle gain.

      community Will you try clascosterone when it gets released?

      in Treatment  14 upvotes 3 months ago
      People are interested in trying clascosterone (Breezula) for hair loss, especially those who are too young for finasteride. Some users express concerns about the cost and prescription requirements, while others discuss alternatives like RU58841.

      community 9 month update (0.5 dut/2.5 oral min)

      in Progress Pictures  64 upvotes 1 month ago
      The user reported improved hair quality and faster growth after switching from finasteride and topical minoxidil to dutasteride and oral minoxidil, despite experiencing significant shedding. They take separate pills daily and are optimistic about future progress.

      community Experiencing Shedding on Phoenix 2in1 and Nizoral for 9 Months

      in Basic Questions  75 upvotes 1 month ago
      The user has been using a Phoenix 2-in-1 pill (1mg finasteride with 3mg minoxidil), nizoral ketoconazole shampoo, and derma rolling for 9 months but continues to experience hair shedding. They are considering adding Rogaine foam and are curious about low-level laser caps for better results.

      community VDPHL01 works really quickly .. apparently?

      in Research/Science  48 upvotes 2 months ago
      VDPHL01 shows faster and stronger hair growth compared to standard minoxidil, with no major side effects reported. Users discuss combining it with other treatments like dutasteride and finasteride for better results, while expressing skepticism about the effectiveness of PP405.

      community 8 months of 0.5 mg dut daily, 14 months of 5 mg oral min

      in Progress Pictures  3 upvotes 2 months ago
      The user has been using 0.5 mg dutasteride daily for 8 months and 5 mg oral minoxidil for 14 months to address hair thinning. Despite some users seeing no change or improvement, the user feels their hairline density has decreased and corners have worsened.

      community Are there any reviews of KX-826 yet?

      in Treatment  1 upvotes 1 year ago
      Pyrilutamide (KX-826) is being discussed as a potential hair loss treatment, with some users reporting no regrowth after three months. It may prevent further hair loss but might not promote regrowth unless combined with Minoxidil.

      community 3 month progress on Manual combi fin/min pill

      in Progress Pictures  19 upvotes 1 year ago
      A user shared their 3-month progress using a combined finasteride and minoxidil pill for hair loss, noting early signs of regrowth. They also use biotin shampoo/conditioner, take Vyvanse and Propranolol, and bleach/dye their hair every 3 weeks.

      community Dutasteride mesotherapy to lower dut dose

      in Finasteride/Dutasteride  1 upvotes 9 months ago
      The conversation is about a user considering reducing their dutasteride dose due to side effects like lower libido and watery semen. They plan to use dutasteride mesotherapy every three months to maintain hair while reducing systemic DHT suppression.

      community Anyone immediately lose hope for gt20029 when they realised it’s developed by kintor

      in Research/Science  7 upvotes 5 months ago
      The conversation discusses various hair loss treatments, including minoxidil, finasteride, dutasteride, pyrilutamide, alfatrodial, and nizoral, with a focus on the potential of new treatments like gt20029 and breezula. There is optimism about novel treatments that don't have systemic effects, although skepticism remains about the effectiveness of some new drugs.

      community Finasteride 1mg daily vs 1.25mg EOD vs 1.25mg 5 days a week

      in Basic Questions  122 upvotes 1 month ago
      The user is treating male pattern baldness with oral minoxidil, ketoconazole, derma rolling, rosemary oil, and topical minoxidil, and is considering adding finasteride. They are debating between three finasteride dosing strategies: 1mg daily, 1.25mg every other day, or 1.25mg five days a week, focusing on efficacy, safety, and cost.

      community Shiseido RCH-01

       5 upvotes 7 years ago
      Shiseido RCH-01 and Replicel's upcoming trial data release. Users discuss expected release timelines and clarify quarter dates.

      community Shedding with topical dutasteride (month 4)

      in Progress Pictures  29 upvotes 1 year ago
      The user shared progress pictures after using topical dutasteride for 4 months, experiencing heavy shedding at month 2, which returned to baseline 1.5 months ago. Previous treatments with topical and oral finasteride and minoxidil were ineffective or caused side effects, and the user is hopeful about the shedding phase indicating potential effectiveness of topical dutasteride.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Alopecia Areata Question

      in Treatment  2 upvotes 5 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.