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GlossaryQuetiapine

antipsychotic medication used to treat schizophrenia and bipolar disorder

Quetiapine, also known by the brand name Seroquel, is an antipsychotic medication used to treat mental health conditions such as schizophrenia, bipolar disorder, and major depressive disorder. It works by altering the actions of certain neurotransmitters in the brain, particularly serotonin and dopamine, to help stabilize mood and reduce symptoms like hallucinations and mood swings.

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community Does finasteride works forever as long as you take it?

in Finasteride/Dutasteride 189 upvotes 1 year ago

Finasteride can maintain hair for many years, but its effectiveness may decrease over time. Some switch to dutasteride or add minoxidil for better results, with side effects like libido changes and ED discussed.

community Upcoming Setipiprant clinical trials hint at systemic daily dosage

23 upvotes 9 years ago

The conversation discusses the safety, tolerability, and efficacy of oral Setipiprant tablets for treating androgenetic alopecia compared to finasteride. It mentions the high cost of Setipiprant on the black market and the trial's end date in September 2017.

community Finally about to start Pyriltamide (ONLY Pyriltamide)

in Chat 63 upvotes 1 year ago

A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.

community Will kintor show pyrilutamide phase 3 trials result this q

in Treatment 2 upvotes 2 years ago

The conversation is about the release of a new phase 3 clinical trial for a year and questioning if the results of the 6-month clinical trials will be shown this quarter. The specific treatment discussed is Pyrilutamide.

community Where to buy setipiprant from ?

in Treatment 2 upvotes 1 year ago

The conversation is about hair loss treatments, specifically setipiprant, which the user is considering after experiencing side effects from finasteride and dutasteride. Another user mentions that setipiprant was ineffective in clinical trials.

community Setipiprant trial results

in Update 13 upvotes 7 years ago

Setipiprant trial for hair loss failed, showing no difference between placebo and treatment. Discussion also noted placebo users reporting side effects.

community Fevipiprant 2019!

15 upvotes 9 years ago

The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

community Setipiprant study updated on ClinicalTrials - anticipated May 9th completion

18 upvotes 7 years ago

The conversation discusses hair loss treatments, specifically Setipiprant, finasteride, and bimatoprost. Setipiprant is suggested for maintenance, while bimatoprost is for regrowth, and combining them with dermarolling is recommended for better results.

community KX-826: My initial thoughts and observations on pyrilutamide...

in Treatment 1 upvotes 1 year ago

The user tried pyrilutamide for hair loss and noticed reduced scalp itch and improved skin but stopped due to mild heart sensations. They plan to update after consistent use, noting improved sleep when applied at night.

community Pyrilutamide - your experience?

in Product 12 upvotes 3 years ago

The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

community Anyone else crying themselves to sleep because of the pyrilutamide fail?

in Technology 42 upvotes 2 years ago

The conversation is about disappointment with pyrilutamide's performance as a hair loss treatment, with some users expressing interest in other treatments like Verteporfin, GT20029, and RU58841, while others suggest sticking with established treatments like finasteride or dutasteride.

community Pyrilutamide ,the molecule’s true nature

in Research 302 upvotes 1 year ago

Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

community About Pyrilutamide Phase II US Trial

in Research/Science 11 upvotes 2 years ago

The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.

community Kintor pyrilutamide presentation?

in Research/Science 12 upvotes 3 years ago

The conversation is about whether the phase 2 results for pyrilutamide, a potential hair loss treatment, were presented at a dermatology convention and inquiries about the completion of phase 3 trials. Specific treatments mentioned include pyrilutamide.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 126 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Best carrier for pyrilutamide?

in Update 9 upvotes 3 years ago

The conversation is about adding a low dose of pyrilutamide to a hair loss treatment regimen. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 52 upvotes 2 years ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community A Technical Question About Pyrilutamide

in Research/Science 5 upvotes 2 years ago

Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

community How is the GT20029 different to pyrilutamide as an androgenic antagonist

in Research/Science 1 year ago

GT20029 and pyrilutamide are both androgen antagonists but work differently; GT20029 degrades the androgen receptor, while pyrilutamide blocks DHT from binding. GT20029 is expected to have similar efficacy to CosmeRNA.

community How long until pyrilutamide or gt20029 get FDA approved?

in Research/Science 7 upvotes 2 years ago

Hair loss treatments pyrilutamide and GT20029 discussed. Pyrilutamide approval in 2 years, GT20029 in 5-6+ years.

community Pyrilutamide available at Actifolic now

in Research/Science 15 upvotes 3 years ago

Pyrilutamide, a new hair loss product with the potential to be more effective than RU58841 and safer than CB, but expensive.

community The New, Improved CB-03-01/Setipiprant Group Buy

28 upvotes 9 years ago

The group buy for CB-03-01, a topical anti-androgen for hair loss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.

community So Pyrilutamide has been postponed by one year. How likely is that to happen to GT20029

in Treatment 28 upvotes 2 years ago

The conversation discusses the delay in the release of a new hair loss treatment, Pyrilutamide, and speculates on potential safety concerns as a reason for the delay. It also mentions GT20029 as another future treatment option, with a release at least five years away, and touches on the avoidance of research chemicals due to uncertainty about their authenticity.

community pyrilutamide log from someone who couldnt take fin/min/ru due to sideeffects

in Progress Pictures 101 upvotes 3 years ago

A user (seblt) who has had side effects from finasteride, minoxidil and RU58841 but is now trying pyrilutamide as a last resort, with other users providing advice and support. They have already seen some baby hairs growing after 10-14 days of treatment and will provide updates in 1-2 weeks.

community Kintor announcement about pyrilutamide phase 3 results in CHINA

in Treatment 15 upvotes 2 years ago

Kintor announced Phase 3 results for pyrilutamide, a hair loss treatment, in China. The conversation is focused on this announcement and its implications for hair loss treatment.

community First patient dosed with Pyrilutamide (Kintor) Phase III

in Research/Science 197 upvotes 4 years ago

First patient dosed with Pyrilutamide (Kintor) Phase III for hair loss treatment. Pyrilutamide differs from approved treatments as it competes with DHT to bind hair follicles, potentially reducing side effects.

community Pyrilutamide US Phase 2 Trial?

in Research/Science 27 upvotes 3 years ago

The Phase 2 trial for Pyrilutamide in the US, which started a year after the China trials, and inquiring about any available information on when it will finish. Treatments discussed include Minoxidil, Finasteride, and RU58841.

community KX-826 Pyrilutamide1% coming soon

in Update 152 upvotes 1 year ago

KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

community Thinking about signing up for the setipiprant clinical trials

4 upvotes 8 years ago

The conversation discusses hair loss treatments, with the original poster considering joining a clinical trial for setipiprant after experiencing side effects from finasteride and disinterest in minoxidil. Some users express skepticism about setipiprant's effectiveness, while others encourage participation in the trial for potential benefits.

community Potentially Positive Pyrilutamide News Coming

in Research/Science 6 upvotes 1 month ago

Kintor Pharmaceutical's stock rise suggests potential positive news about Pyrilutamide, a topical anti-androgen. GT20029 may also compete with existing treatments like finasteride and dutasteride.