Hairloss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
The conversation discusses hairloss and the potential impact of diet and lifestyle changes, particularly increased protein intake, on hair health. The original poster shared their experience of improved hair appearance after weight loss and dietary changes, despite skepticism from others about lighting differences in photos and the effectiveness of diet alone without finasteride or minoxidil.
Creatine may cause hairloss in some individuals, though there is no scientific consensus. Personal experiences vary, with some reporting increased shedding and others seeing no effect.
A permanent hairloss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.
Creatine does not directly cause hairloss but may increase DHT levels, potentially worsening hairloss in those predisposed to male pattern baldness. Users have mixed experiences, with some reporting increased shedding and others seeing no effect.
Creatine does not cause hairloss, despite many users reporting personal experiences of hair shedding. Scientific evidence shows no link between creatine and increased hairloss or hormone changes.
There have been no new effective hairloss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.
Hairloss treatments, including minoxidil, dermarolling, finasteride, dutasteride, hair transplants, hair systems, and shaving the head. The conversation covers various opinions on these treatments and mentions possible side effects as well as alternatives like wigs, vitamins, and lifestyle changes. The post expresses disappointment that there has been no major breakthrough in the field of hairloss treatments despite decades of research.
A dental technician claims malocclusion causes pattern hairloss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.
The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hairloss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hairloss while maintaining muscle mass, and will continue using the other treatments.
User experienced hairloss after taking creatine with finasteride for 8 years. Others shared similar experiences, but some suggested it could be a minoxidil shed.
Creatine monohydrate's potential link to hairloss, with mixed opinions on its effects. Treatments like minoxidil, finasteride, and RU58841 are discussed.
Quitting vaping significantly reduced hairloss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hairloss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.
The user switched from finasteride to dutasteride for hairloss but faced increased shedding and anxiety, regretting not staying with finasteride longer. Other users shared mixed experiences, advising patience with dutasteride, as it may take up to a year to show results.
The user shared their personal experience with hairloss, hormone imbalances, and treatments including testosterone boosters, natural estrogen blockers, and DHEA. They suggest that low-dose finasteride and natural hormone therapy could reduce hairloss with fewer side effects.
Scalp biopsies are crucial for diagnosing hairloss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hairloss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
The conversation discusses hair shedding experienced by users undergoing hairloss treatments, including finasteride, minoxidil, and microneedling. Many users report experiencing significant shedding around the 8-12 month mark, which is considered a normal part of the hair regrowth process, with expectations of stronger regrowth following the shedding phase.
Hairloss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.
Hairloss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.
The post discusses using Sandalore as a potential hairloss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.
The user shared a 10-month hairloss treatment routine using Finasteride, ketoconazole shampoo, and Red Light Therapy, noting significant progress and considering adding Dutasteride. They experienced initial side effects and changes in libido, but overall reduced hair shedding and regrowth, especially at the temples.
Hairloss treatments discussed include Minoxidil, Finasteride, and RU58841. Pyrilutamide Phase 2 results are expected in June 2022, with hopes for a better alternative to current treatments.
Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hairloss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hairloss.
PP405 is being discussed as a potential hairloss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.
RU58841 is discussed as a topical anti-androgen for hairloss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hairloss by blocking DHT and promoting hair growth.
Finasteride is the most effective treatment for reducing DHT and addressing hairloss compared to fish oil and saw palmetto. Topical treatments like RU58841 and minoxidil are also discussed, but finasteride remains the most effective option.
The post discusses a user's experience with hairloss treatments, specifically topical finasteride, minoxidil, and micro-needling, and their plan to switch to oral versions and add Dutasteride. The conversation includes various responses, with some users sharing their own experiences and side effects, and others expressing desire for a more permanent hairloss solution.