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      community clascoterone powder to topical diy

      in Product  3 upvotes 1 month ago
      The conversation is about making a topical solution from clascoterone powder, with references to using a RU58841 mixing guide for guidance. Concerns about product authenticity and bulk purchase requirements are also discussed.

      community Anagenic is trying to compound Gt20029

      in Treatment  56 upvotes 3 years ago
      The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

      community making a clascoterone lotion from powder

      in Technology  2 upvotes 1 year ago
      A user is considering making a 2% clascoterone lotion from powder due to unavailability in their location. They plan to mix clascoterone powder with retinol lotion and use literature to determine the correct dosage.

      community Chat is this real? Compound called clascoterone

      in Research/Science  588 upvotes 6 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community Why is no one talking about alfatradiol?

      in Treatment  25 upvotes 1 year ago
      Alfatradiol is discussed as a hair loss treatment with minimal side effects, but its effectiveness is debated, and it's not widely known or available outside Germany. Some users report side effects like gyno and ball ache, while others find it effective in stopping shedding and itching.

      community How’s RCH-01 doing?

      in Treatment  6 upvotes 6 years ago
      RCH-01's progress is uncertain, and there's skepticism about its effectiveness. Users are losing hope in this treatment.

      community PP405 (Non) Update - Feb 2025

      in Research/Science  34 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community PSA: Get your Vitamin D levels checked!

      in Treatment  115 upvotes 3 years ago
      A user improved their hair health by taking 50,000 IU of vitamin D3 weekly due to a deficiency. Others discussed the potential link between vitamin D and hair growth, with some sharing similar experiences and emphasizing the importance of monitoring vitamin D levels and consulting with doctors.

      community Severe Vitamin D deficiency?

      in Chat  15 upvotes 5 years ago
      The conversation is about severe Vitamin D deficiency and its potential link to hair loss. The user is already using oral finasteride, topical finasteride, and topical minoxidil for aggressive hair loss.

      community Anyone used CB-03-01 (clascoterone), is it worth it, too risky??

      in Research/Science  2 upvotes 2 years ago
      The user experienced side effects from low-dose topical finasteride and is considering using clascoterone (CB-03-01) despite concerns about its risks and cost. They seek advice on its effectiveness and potential side effects compared to other treatments like alfatradiol and fluridil.

      community Success: My Doc prescribed me 0.1% Alfatradiol

      in Treatment  13 upvotes 1 year ago
      A user shared their success in getting a prescription for 0.1% Alfatradiol, a topical treatment for hair loss similar to finasteride but with fewer side effects. They found a pharmacy to compound it and will update on the results.

      community Vitamin C and hair growth PH levels

      in Product  33 upvotes 4 years ago
      The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Quitting Alfatradiol after 4 months

      in Product  5 upvotes 1 year ago
      The user stopped using Alfatradiol after 4 months due to no hair improvement and side effects like dry scalp and gallbladder pain. They are considering trying topilutamide, which is suggested as an alternative.

      community Having Ru58841 mailed to my house

      in Research/Science  1 upvotes 4 months ago
      RU58841 can be ordered as a powder and compounded at home, but it should be stored at room temperature to avoid crystallization. Pyraulatmide may follow a similar principle.

      community Vitamin D advice I received after seeing my blood work.

      in Research/Science  88 upvotes 4 years ago
      The conversation discusses the importance of taking vitamin D with food for better absorption and its potential role in hair loss. Some users also suggest taking vitamin D with K2, getting sunlight, and using finasteride for hair loss treatment.

      community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

      in Research/Science  5 upvotes 2 years ago
      The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.

      community Anyone here used spirolactone/cyproterone acetate/bicalutamide?

      in Chat  4 upvotes 9 months ago
      The conversation discusses the use of spironolactone, cyproterone acetate, and bicalutamide for hair loss, with concerns about side effects like gynecomastia and depression. Topical spironolactone is considered safe for men and effective when combined with regular treatments.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.