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      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 1 year ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Lost ground on Dut, Min, RU, etc (5 yrs… 2021->2026)

      in Progress Pictures  16 upvotes 2 weeks ago
      The user has been using a combination of treatments including Dutasteride, Minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy to address hair loss but continues to experience shedding and density loss. Despite high testosterone and iron levels, the user is frustrated with the lack of improvement and is considering adjusting treatment or exploring other options like a hair transplant.

      community What hormones/vitamins should I test for?

      in General  51 upvotes 9 months ago
      The user plans to test for DHT, total testosterone, free testosterone, E2, SHBG, and prolactin while supplementing with vitamin D and monitoring ferritin levels. They are experiencing hairline thinning and are seeking advice on whether their approach is excessive or lacking.

      community What are your thoughts on pre-finasteride blood work?

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The user is considering resuming finasteride after a 6-month break and is debating the necessity of extensive blood work, including hormone and health markers, to establish a baseline. They are unsure if the tests are necessary since they experienced no side effects previously.

      community Redensyl formula recommendation

      in Product  2 upvotes 1 year ago
      A user is seeking a hair loss formula containing Redensyl and Capixyl without caffeine, Saw Palmetto, or other herbs. They want recommendations for such a product.

      community 5 months of Ru58841 & 5% minoxidil

      in Progress Pictures  25 upvotes 1 year ago
      The post discusses using RU58841 and 5% minoxidil for hair loss treatment, with RU applied to the temples and crown, and minoxidil used twice daily. Users debate the effectiveness of RU58841 compared to minoxidil alone.

      community Reaction to Minoxidil Foam version

      in Minoxidil  1 upvotes 1 year ago
      User experienced itching, redness, and hives from Minoxidil foam and is questioning if they are allergic to Minoxidil or another ingredient. They have switched to oral Finasteride.

      community 3 Mo Progress Fin/Min- Sept.-Dec

      in Is this regrowth?  21 upvotes 1 year ago
      The conversation is about a user sharing their positive progress with hair regrowth using oral minoxidil, biotin, finasteride, and other supplements. The user also mentions using a HIMS oral fin/min combo and receives advice and encouragement from others.

      community Question about RU58841 in minoxidil

      in Minoxidil  5 upvotes 5 years ago
      The user is considering adding RU58841 to liquid minoxidil without propylene glycol (PG) due to an allergy and is asking if this combination is effective and if PG is necessary. They have been using finasteride and minoxidil foam, plan to use RU58841 with liquid minoxidil in the evening, and continue finasteride.

      community Experience with Rootbiotec or Anagain

      in Treatment  1 upvotes 4 years ago
      The conversation discusses experiences with hair loss treatments containing RootBioTec and Anagain. Users share their results and compare these treatments to Minoxidil, finasteride, and RU58841.

      community Yet another hrt update (4 months estradiol and spiro + > 4 years of fin and min) (you should absolutely not take estradiol and spiro if you look manly and want to continue to look manly)

      in Progress Pictures  5 upvotes 1 year ago
      The conversation discusses hair loss treatments, including finasteride, minoxidil, estradiol, and spironolactone, with a focus on their effects on hair regrowth and gender transition. The original poster shares their personal experience with these treatments, emphasizing that estradiol and spironolactone should not be used by those who want to maintain a masculine appearance.
      My hair regrowth journey

      community My hair regrowth journey

      in Journals / Progress Pictures  73 upvotes 7 months ago
      The user is documenting their hair regrowth journey using oral finasteride, topical minoxidil, ketoconazole, dermarolling, biotin shampoo, and rosemary oil. They are committed to maintaining this regimen to track progress.

      community 2 years on treatment (stack update)

      in Progress Pictures  460 upvotes 1 year ago
      A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.

      community Tropical growth stimulants other than minoxidil

      in Treatment  10 upvotes 1 year ago
      The conversation discusses alternative hair growth treatments to minoxidil, including Stemoxydine, Tretinoin, adenosine, Baicalin, castor oil, Latanoprost/bimatoprost, and Redensyl. Users share their experiences and opinions on the efficacy of these treatments.

      community 8 weeks in with microneedling and minoxidil/tretinoin

      in Progress Pictures  95 upvotes 1 year ago
      The user is using a combination of microneedling, minoxidil, tretinoin, scalp massages, and red light therapy to address hair loss, with a focus on the hairline and temples. They emphasize the importance of scalp massages and have seen regrowth, attributing success to their comprehensive routine.

      community Tretinoin can make it worse!!!

      in Chat  7 upvotes 2 years ago
      Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

      community Dear RU58841 Users- How did it go?

      in Chat  4 upvotes 4 weeks ago
      RU58841 is used by some for hair loss when finasteride and minoxidil are ineffective. Users report mixed results, with some experiencing side effects like chest pain and mood changes.

      community Extreme shedding after ~1 year on 5% topical minoxidil — normal or problem?

      in Minoxidil  4 upvotes 2 months ago
      A 17-year-old using 5% topical minoxidil experienced significant hair shedding after a year, possibly due to a "synchronization shed" and deficiencies in vitamin D and iron. Recommendations include continuing minoxidil, optimizing vitamin D and iron levels, and reducing tretinoin use if scalp irritation occurs.

      community Who won’t respond to minoxidil? (Studies)

      in Research/Science  35 upvotes 1 month ago
      Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

      community 6 Months Progress - its working?

      in Is this regrowth?  20 upvotes 1 year ago
      User is using Finasteride, oral Minoxidil, Microneedling, Dutasteride, KX-826, and topical Minoxidil for hair regrowth. Experiencing heartburn from oral Minoxidil, others suggest stopping it and continuing with other treatments.

      community Good lord! Serioxyl stemoxydine smells TERRIBLE

      in Product  14 upvotes 2 years ago
      The conversation is about a user complaining about the strong smell of a stemoxydine serum used for hair loss. Other users suggest that the product might be counterfeit due to its unpleasant odor.