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      community Continued loss after 2 years on treatment

      in Finasteride/Dutasteride  7 upvotes 3 years ago
      The user has been on Dutasteride and Minoxidil for hair loss but is experiencing continued thinning and is considering increasing Minoxidil usage, switching to oral Minoxidil, increasing Dutasteride dosage, or trying other treatments like pyril or RU58841. They are seeking advice from others with similar experiences.

      community Telogen Effluvium lasting longer than two years??

       4 upvotes 6 years ago
      The conversation discusses severe hair loss, possibly due to telogen effluvium or male pattern baldness, lasting over three years. Suggested treatments include minoxidil, finasteride, and dermarolling, with a recommendation to consult a dermatologist.

      community Topical spironolactone question

      in Product  2 upvotes 3 years ago
      User started using topical spironolactone on scalp and face, experienced fever feeling and sluggishness. Asks if side effects are normal or systemic.

      community Are these new hair loss treatments ever gonna release?

      in Technology  44 upvotes 3 weeks ago
      Hair loss treatments like Breezula and PP405 are delayed, with approvals taking years, while existing treatments like minoxidil and finasteride remain popular. New treatments like Clascoterone and Veradermics are in trials, but high costs and lengthy approval processes slow their release.

      community Kintor starts a new Phase 3 for Pyri... (1+ year)

      in Research/Science  15 upvotes 2 years ago
      The conversation discusses Kintor's initiation of a new Phase 3 trial to assess the long-term safety of Pyrilutamide (KX-826) for hair loss, which will last 52 weeks. Specific treatments mentioned include Pyrilutamide.

      community From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA.

      in Treatment  5 upvotes 1 week ago
      A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.

      community Reflex Hyperandrogenicty: How I recovered from it

      in Treatment 2 years ago
      The user experienced severe hair shedding from RU58841 and recovered by stopping its use and starting treatments including Minoxidil, Rosemary Verbenone, Stemoxydine, Aminexil, copper peptide serum, and specific shampoos. They also consistently used oral Finasteride and plan to try Minoxidil 10%.

      community Effects of 2% vs 5% min for sebderm

      in Minoxidil  1 upvotes 1 year ago
      Switching from 2% liquid minoxidil to 5% foam minoxidil reduced scalp irritation but increased eyebrow flakiness and thinning. The user speculates that propylene glycol in the liquid formulation might have been protecting against seborrheic dermatitis while causing contact dermatitis.

      community Ru58841 made my hair worse

      in General  138 upvotes 11 months ago
      RU58841 worsened hair condition, causing thinning and unusual patterns. The user stopped using it two months ago but hasn't seen recovery, and there's speculation about androgen receptor upregulation.

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 3 years ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community Progress finasteride and minoxidil + problem

      in Progress Pictures  2 upvotes 1 year ago
      The user is experiencing hair improvement in the central and back areas after using finasteride, minoxidil, and a galenic lotion, but the temple area is worsening. They suspect the lotion might be causing the issue and are considering stopping its use.

      community Do minoxidil have * no * benefits when discontinued?

      in Minoxidil  1 upvotes 8 months ago
      Minoxidil initially showed great results for hair loss but plateaued, leading to the addition of finasteride and dutasteride. The user is considering restarting minoxidil and is concerned about its long-term effects on skin.

      community Any scalp-friendly min+ru products available in UK?

      in Product  1 upvotes 6 months ago
      The user is seeking recommendations for scalp-friendly minoxidil and RU58841 products available in the UK, as previous products caused scalp inflammation. They mention issues with RUDirect and MinoxidilMax products.

      community Does Pyrilutamide lowers sebum production?

      in Treatment  2 upvotes 4 months ago
      Pyrilutamide's effect on sebum production and scalp inflammation is unclear, with users noting no significant changes. Isotretinoin is mentioned as effective for reducing sebum, while Dutasteride and various shampoos have limited impact on oiliness and seborrheic dermatitis.

      community Has anyone regrown hair after adding tretinoin?

      in Minoxidil  7 upvotes 1 year ago
      Adding tretinoin to minoxidil may help non-responders but likely won't improve results for those already responding to minoxidil. The user plans to try tretinoin with minoxidil and finasteride to see if it enhances hair regrowth.

      community Tretinoin for some men(not all) can cause non-telogen effluvium hair loss

      in Research/Science  4 upvotes 9 months ago
      Tretinoin can cause non-telogen hair loss in some men by inducing catagen-like changes in hair follicles and through retinoid toxicity, especially when used with minoxidil. Some users report hair loss even when using retinoids on the face, while others experience benefits when combined with treatments like finasteride and minoxidil.

      community Second shed and more abnormalities

      in Treatment  1 upvotes 1 year ago
      The user has been using oral finasteride for 15 months and oral minoxidil for 6 months, and developed alopecia areata, for which a dermatologist prescribed calcipotriol/betamethasone. The treatment is helping, but the user is experiencing another shedding phase and is concerned about the effects of the steroid cream and the cause of hair loss.

      community Continue RU58841 or hair system for receding hair line?

      in Progress Pictures  9 upvotes 1 year ago
      A user is considering whether to continue using RU58841 or switch to hair system patches for a receding hairline, while already using finasteride, oral minoxidil, and microneedling. Another user suggests buying RU58841 in powder form to save money and notes the original poster's hair has significantly improved.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  13 upvotes 5 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community Alopecia Areata Question

      in Treatment  2 upvotes 5 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community Finasteride gives me seb derm. Thoughts on zinc or other options?

      in Chat  15 upvotes 3 years ago
      A user with diffuse hair loss after taking accutane, which might have triggered genetic predisposition to AGA; their experience taking finasteride and experiencing side effects of increased oil production, increased sex drive, worsening hair texture; they are considering zinc supplementation with finasteride or other treatments such as alfatradiol or spironolactone.