PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.
The user is experiencing significant hair shedding after four months of using topical finasteride and minoxidil, questioning if it's a normal shedding phase or if the treatment isn't working. They are considering switching to oral treatments and have increased their finasteride concentration, while also using keto and caffeine shampoos.
Creatine does not increase DHT levels or cause hair loss. Personal experiences vary, but scientific evidence shows no link between creatine and hair loss.
Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.
Training scalp muscles to absorb more DHT is suggested as a hair loss solution, but users debate its effectiveness compared to medications like dutasteride and finasteride. Concerns about side effects of DHT blockers, such as reduced libido, are discussed, with some advocating for natural remedies like scalp massages and healthy living.
A 22-year-old experiencing hair loss, initially attributed to stress, found temporary relief with minoxidil but faced increased shedding after stopping and restarting the treatment. The advice given suggests the hair loss may be due to androgenic alopecia rather than stress, recommending consistent use of minoxidil and considering finasteride, with a suggestion to seek a second opinion from another dermatologist.
A potential treatment for alopecia involving a protein that calms hair follicles has shown promise in rats, but skepticism remains about its applicability to humans. Many users express doubt about the timeline for effective hair loss treatments, comparing it to past unfulfilled promises.
A 23-year-old male is using topical minoxidil and oral finasteride for hair regrowth, noticing some progress on his temples and seeking advice on whether this indicates overall scalp improvement. Users suggest patience, as regrowth can take time, and advise against a hair transplant, noting that the current treatment seems effective.
Finasteride and dutasteride are significantly cheaper in India, leading to substantial savings for users. There are discussions on the effectiveness of oral minoxidil and finasteride for hair loss, with concerns about the quality of generic medications.