Hair loss treatments discussed include Minoxidil, finasteride, and RU58841. The conversation humorously reflects on past hair loss solutions and the potential of hair cloning.
User got a hair transplant and it improved their life. Transplanted hair lasts, but medication like finasteride is needed to maintain non-transplanted hair.
New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.
The conversation is about the potential of SCUBE3 to regrow a juvenile hairline. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.
A 23-year-old male with aggressive hair loss has tried various treatments, including minoxidil (both topical and oral), dutasteride, multivitamins, and PRP sessions, but has seen limited success. He is considering a hair transplant and seeks advice on whether this is a reasonable approach.
A 33-year-old male with a receding hairline is advised to start with finasteride to block DHT and consider minoxidil for promoting hairgrowth. Other treatments like copper peptides and serums are deemed less effective, and ketoconazole shampoo is suggested for scalp health.
The user started losing their hair at 16 and got a hair transplant. They used Minoxidil and finasteride as treatments. The transplant has held up well and they have not experienced graft loss.
SCUBE3, a protein linked to hairgrowth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hairgrowth therapy.
A man lost his transplanted hair despite using minoxidil because he wasn't on a DHT blocker like finasteride, which is essential to prevent further hair loss. The conversation emphasizes that hair transplants are not a cure and require maintenance with medications to preserve results.
User experienced hair loss on the top of the head for 2 years, noticed improvement after adding a smoothie with various fruits, vegetables, and seeds to their diet. They observed increased hairgrowth after 2 weeks of this dietary change.
The user is using oral minoxidil, dutasteride, finasteride, and biotin for hair regrowth. They experience side effects like ED but are willing to continue for hair preservation.
Some individuals experience side effects from 5AR inhibitors like finasteride and are considering hair transplants without these medications, with some opting for surgeons like Dr. Zarev. Others are exploring alternative treatments and waiting for new medications in development, while some discuss managing side effects through lifestyle changes or additional medications.
A user is struggling with hair loss at 17 and has been using finasteride for 5 months and minoxidil for 11 months without seeing regrowth. Other users encourage continuing treatment, sharing their own experiences with finasteride, minoxidil, and dermarolling, and emphasizing patience and acceptance.
Hair loss treatments discussed include microneedling, minoxidil, tretinoin, finasteride, dutasteride, pumpkin seeds, saw palmetto, and scalp massage. The consensus is that finasteride or dutasteride is necessary for significant regrowth, while other methods may only slow hair loss.
The conversation discusses using finasteride or dutasteride to reduce DHT, CosmeRNA to target androgen receptors, and Minoxidil as a vasodilator for hairgrowth. The regimen aims to maintain hair by addressing DHT-AR ratio and continuous Minoxidil use.
Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.
A 20-year-old experiencing hair loss since age 16 is using finasteride and minoxidil and is considering future hair transplants. Discussions include the potential for multiple transplants, the use of body hair for coverage, and the importance of treatments like dutasteride and scalp micropigmentation for maintaining hair density.
A 19-year-old experiencing early hair loss started using finasteride to address diffuse thinning, despite concerns about potential side effects. They also use T/Gel and OGX Thick and Full shampoo, and have a dermatologist appointment scheduled to explore possible allergies.
The conversation discusses hair thinning and treatments like finasteride, dutasteride, oral and topical minoxidil, and RU58841. Users share experiences with retrograde alopecia, hair transplants, and stress-related hair loss, while also considering thyroid issues and other potential causes.
The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.
ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.
Topical sodium valproate may promote hairgrowth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.
The user experienced a receding hairline and tried minoxidil, which may have slowed the process but caused puffy eyes. They are hesitant to use finasteride and suspect oily dandruff might be an aggravator.
People are hopeful for a permanent hair loss solution by the 2030s, considering options like hair cloning and treatments like pp405. Synthetic hair transplants have been attempted but are not effective long-term.
Stress can lead to hair loss by affecting hair-follicle stem cells, and this loss is harder to recover from if one has male pattern baldness (MPB). Treatments like finasteride and minoxidil are used to address hair loss, but stress-related hair loss differs from androgenic alopecia.
The user shared their 4-year hair regrowth journey using finasteride, minoxidil, RU58841, microneedling, and Nizoral shampoo. They plan to adjust their RU58841 dosage and are considering a hair transplant if current methods don't yield desired results.
A 17-year-old experiencing hair thinning uses dermarolling with rosemary oil and plans to start finasteride at 18. A reply suggests using finasteride and minoxidil due to high DHT sensitivity.
PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.