PP405 is a topical gel being tested for hair regrowth in adults with androgenetic alopecia. Volunteers aged 18-55 are needed for a 16-week trial in several US locations.
DHT promotes beard growth but causes scalp hair loss due to inflammation and fibrosis. Treatments like finasteride and minoxidil help with hormonal signals and blood flow but don't address underlying inflammation.
A user's hair growth progress over 5 months using Fin 2.5mg gel and Redensyl serum, with the user noticing baby hairs and an improvement in thickness. Another user asked what redensyl serum was and the response was appreciation for noticing the hair loss early on.
The conversation discusses the progress and potential of hair cloning by Stemson Therapeutics, questioning if it will be realized in the next 5-10 years or if it's just false hope. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.
A user started using RU58841 a month ago after using finasteride and minoxidil for nearly three years, hoping for hair regrowth at the temples. Other users suggest vitamin B supplements and microneedling to improve hair thickness, and one mentions the possibility of a hair transplant for the temples.
The user is pleased with 4 months of progress using topical minoxidil 5%, finasteride 1mg, and dermarolling 1mm weekly. They are asking if they should expect more results before one year and if they should switch to oral minoxidil.
The user has been using topical minoxidil and dermarolling for hair regrowth but is hesitant to start finasteride due to potential side effects. Many suggest adding finasteride for better results in addressing DHT-related hair loss.
A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.
The conclusion of the conversation is that the user, djamezz, has experienced significant regrowth and improved density in their hairline by using treatments such as RU (RU58841), dut (dutasteride), and Inkey's Caffeine Scalp treatment. They are satisfied with their progress and do not plan to cut off their hair.
The user shared a 6-month progress update on hair loss treatment using Dutasteride (0.5mg), Minoxidil (5%), and Dermanator 2. They reported improved hair density and coverage, especially in the crown/mid-scalp, and are focusing on enhancing the hairline.
The conversation is about a user sharing their hair regrowth progress using dutasteride, topical minoxidil, and weekly derma stamping. The user reports significant improvement without side effects, and others discuss the effectiveness and techniques of derma stamping.
The conversation discusses hair loss treatment using daily topical minoxidil and finasteride, daily 0.5mm dermarolling before application, and 2% ketoconazole shampoo three times a week. Users believe dermarolling enhances the absorption of the treatments and expect significant improvements over time.
User tried dermarolling for hair loss and shared progress pictures. Some suggest adding finasteride and minoxidil, while others debate effectiveness and frequency of dermarolling.
The conversation is about a user's hair loss treatment regimen, which includes daily finasteride, topical minoxidil, derma rolling, and Nizoral shampoo. Opinions vary on the effectiveness of the regimen, with some users suggesting additional treatments like oral minoxidil and dutasteride, while others debate the presence of a scalp fungus and the impact of microneedling.
Significant hair regrowth was achieved using RU58841, minoxidil, and microneedling during a high-dose steroid cycle. The user reported no side effects from RU58841 and plans to continue the regimen.
The user started using minoxidil foam daily after two years on finasteride and is managing seborrheic dermatitis with antifungal shampoo. They seek advice on moisturizing products that won't worsen their condition, with suggestions including gentle shampoos and light ceramide serums.
The user plans to use a combination of tretinoin, topical minoxidil, and topical finasteride for hair loss treatment. They seek advice on application order, timing, and tretinoin dosage.
The user reports promising hair regrowth without using finasteride, focusing instead on microneedling, dermarolling, minoxidil, tretinoin, scalp massages, and red light therapy. They emphasize consistency and a healthier, side-effect-free approach.
The conversation is about using a 0.5 mm dermaroller for microneedling alongside finasteride and minoxidil for hair loss treatment. The user seeks advice on different dermarollers and how often to replace them.
The user reports hair regrowth using Dutasteride, oral and topical Minoxidil, RU58841, a derma stamp, and a derma roller, attributing their knowledge to this forum. They did not try Finasteride and note a difference in hair quality between new growth and existing hair.
The user experienced improved hair density and thickness after using finasteride and dermarolling for 2.5 years but noticed hair loss when doing anaerobic exercise. They increased their finasteride dose and continued dermarolling but are considering not starting minoxidil due to its perceived hassle and uncertain long-term benefits.
A 21-year-old is experiencing hairline recession and is using finasteride, saw palmetto, gelatin, topical minoxidil with retinoic acid, derma stamping, and scalp massage to address it. Suggestions include adding oral minoxidil, vitamin D3 with K2, and maintaining the current regimen for a year.
The user has been using Finasteride 1mg, Topical Foam Minoxidil 5%, and a DermaRoller weekly for 4 months to combat low hair density. Despite initial shedding, they have seen satisfactory progress and reduced shedding recently.
The user had a hair transplant with 2,000 grafts in 2017, and after four and a half months of using finasteride, minoxidil, derma rolling, and Boton shampoo, they are seeing hair regrowth including the return of their widow's peak. They are considering switching to RU58841 and a deeper derma rolling treatment.
A treatment containing Wnt and Follistatin was found to be safe and effective for hair regrowth in a Phase 1 clinical trial. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.
The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.
User doing PRP with exosomes for hair loss, sees possible regrowth after two treatments. Another user suggests providing before and after pictures for better assessment.
The user switched from finasteride to dutasteride for hair loss and saw significant improvement in under two months. They also microneedle, take supplements including collagen and vitamin D3, use ketoconazole shampoo, and noticed accidental hair regrowth with retinol application on their face.
A user's progress with hair loss treatments, including Dutasteride, Minoxidil (oral and topical), Microneedling, and RU58841, which resulted in positive results after 5 months. Another user commented on the faster growth at the front compared to the crown.