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      community Isotretinoin and Tretinoin difference

      in Product  2 upvotes 1 year ago
      Isotretinoin and tretinoin are different; isotretinoin can cause hair loss and has more side effects. Tretinoin may affect minoxidil absorption, and users suggest waiting before applying minoxidil.

      community Minoxidil Beard Stack | Azelaic Acid, Tretinoin

      in Treatment  13 upvotes 3 years ago
      The conversation discusses using Minoxidil combined with Azelaic Acid and Tretinoin to promote beard growth. Specific treatments mentioned are Minoxidil (Min), Azelaic Acid, and Tretinoin.

      community Alfatradiol Experience (2 months)

      in Treatment  12 upvotes 5 years ago
      User experienced side effects from oral finasteride and tried topical Alfatradiol for hair loss. Alfatradiol provided maintenance without significant regrowth, and user suggests it as an alternative for those struggling with finasteride side effects.

      community M29 Dut/Min/Microneedle/Tretinoin

      in Is this regrowth?  22 upvotes 1 year ago
      A user has been using finasteride since 2018, switched to dutasteride, and added minoxidil, microneedling, and a tretinoin/spiro compound. They are pleased with the results and hopeful for more improvement.

      community Strategies for Treatment Resistant Androgenic Alopecia

      in Treatment  5 upvotes 2 months ago
      The conversation is about a person experiencing treatment-resistant androgenic alopecia despite using high doses of dutasteride and minoxidil, along with other treatments like microneedling and purilutamide. Suggestions include considering a hair transplant, checking medication authenticity, and exploring other treatments like RU58841 or topical estradiol.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community could Tretinoin alone cause regrowth?

      in Treatment  7 upvotes 3 years ago
      The user has maintained their hairline with finasteride for 5 years and saw no results from minoxidil. They are inquiring if tretinoin alone can cause hair regrowth.

      community Patent for topical resveratrol and melatonin for AGA

       4 upvotes 6 years ago
      The conversation discusses a patent for using topical resveratrol and melatonin to treat androgenetic alopecia (AGA) and also mentions interest in topical sulforaphane as a treatment.

      community new way to activate stem cells to make hair grow

       45 upvotes 7 years ago
      Stem cell-related treatments and drugs like RCGD423 and WAY are being tested for hair growth. Clinics are conducting tests on patients who haven't had previous treatments.

      community Pyrilutamide US Phase 2 Trial?

      in Research/Science  27 upvotes 3 years ago
      The Phase 2 trial for Pyrilutamide in the US, which started a year after the China trials, and inquiring about any available information on when it will finish. Treatments discussed include Minoxidil, Finasteride, and RU58841.

      community Does Tretinoin work? Can somebody share their experience

      in Chat  2 upvotes 5 months ago
      Tretinoin can increase hair follicles and is used alongside minoxidil and finasteride for hair growth, though it may cause skin peeling. Users report varying results, with some experiencing regrowth and others questioning its efficacy for hair.

      community How to Add Tretinoin to 2 in 1 combo ?

      in Treatment  2 upvotes 1 year ago
      A user wants to add tretinoin to their nightly minoxidil and finasteride combo to increase effectiveness. They seek advice on how to mix tretinoin with the existing treatment.

      community Any positive responses for Diffuse Thinner with Retrograde using Fin/Min/Dut

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      People with diffuse thinning and retrograde hair loss are discussing treatments like finasteride, minoxidil, and dutasteride, with some reporting improvements and others experiencing issues like scalp inflammation and increased sebum. Suggestions include addressing scalp inflammation, considering gut health, and possibly using topical antiandrogens or micro-needling.

      community (Serious) News and discussion on potential treatments

      in Treatment  28 upvotes 1 year ago
      Current hair loss treatments include finasteride, dutasteride, minoxidil, and derma rolling. New treatments like TDM-105795, GT20029, and others show promise but require more testing and time before approval.

      community 8 Months of Treatment with Subpar Results

      in Is this regrowth?  23 upvotes 2 months ago
      The user has been using Dutasteride, Minoxidil, Ketoconazole, and RU58841 for hair loss but sees subpar results. Suggestions include adjusting treatments, considering a hair transplant, and addressing scalp inflammation.

      community Has anyone regrown hair after adding tretinoin?

      in Minoxidil  7 upvotes 1 year ago
      Adding tretinoin to minoxidil may help non-responders but likely won't improve results for those already responding to minoxidil. The user plans to try tretinoin with minoxidil and finasteride to see if it enhances hair regrowth.

      community HMI-115 question about potential earliest access

      in Research/Science  10 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.

      community 2 years on treatment (stack update)

      in Progress Pictures  461 upvotes 1 year ago
      A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.