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      community RU58841 and Min - topical 50 mg each day

      in Progress Pictures  6 upvotes 2 years ago
      The conversation is about a person's hair improvement after 14.5 months using RU58841 and Minoxidil topically at 50 mg each day, with noticeable hairline improvement but incomplete crown area recovery. The person struggles to take good pictures of their crown area.

      community Am discouraged, tried just about everything....

      in Chat  4 upvotes 1 year ago
      The user has tried finasteride, minoxidil, dutasteride, microneedling, retinol, topical finasteride, and ketoconazole for hair loss but continues to experience hair recession. They are considering adding oral minoxidil or RU58841 and are unsure about the next steps.

      community New stack I started this year has ruined my hair

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      Switching from finasteride and topical minoxidil to oral minoxidil and dutasteride worsened hair condition, leading to frustration and heart issues, prompting a return to topical treatments and the addition of tretinoin. Patience and consistency are advised, as these treatments can take years to show results, and abrupt changes may cause shedding.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community Extreme shedding after ~1 year on 5% topical minoxidil — normal or problem?

      in Minoxidil  4 upvotes 2 months ago
      A 17-year-old using 5% topical minoxidil experienced significant hair shedding after a year, possibly due to a "synchronization shed" and deficiencies in vitamin D and iron. Recommendations include continuing minoxidil, optimizing vitamin D and iron levels, and reducing tretinoin use if scalp irritation occurs.

      community Running Gear- Preemptive Treatment

      in Product 6 months ago
      A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

      community Any Microneedling non-responders figure it out by experimenting?

      in Microneedling  1 upvotes 6 months ago
      The conversation discusses experimenting with microneedling for hair loss, specifically addressing non-responsiveness and the use of topical treatments like dutasteride, minoxidil, and tretinoin. The user seeks advice on effective frequency and depth combinations for better results.

      community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

      in Treatment  4 upvotes 2 years ago
      Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

      community Topical solutions combining minoxidil and finasteride?

      in Treatment  2 upvotes 9 months ago
      A user is seeking advice on creating a topical solution combining minoxidil, finasteride, and tretinoin for hair loss, and is unsure about optimal concentrations and availability. Another user shares their custom formula with tretinoin 0.015%, finasteride 0.025%, and minoxidil 5%, and mentions taking oral dutasteride 0.25mg daily.

      community Dutasteride 1 year regression. Depressing. (With pictures for proof)

      in Progress Pictures  14 upvotes 2 years ago
      A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

      community If I can’t tolerate 5ari, should I try Pyrilutamide 1%?

      in Treatment  5 upvotes 11 months ago
      The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alpha reductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.

      community Oral minoxidil can causes age skin?

      in Minoxidil  8 upvotes 3 years ago
      Oral minoxidil may cause skin aging, such as dark circles. To counteract aging, use tretinoin at night and broad-spectrum sunscreen during the day.

      community Starting topical DUT soon!

      in Finasteride/Dutasteride  4 upvotes 4 years ago
      An 18-year-old male stopped using finasteride due to side effects and plans to start topical dutasteride, considering it a potential solution with fewer side effects. He continues using minoxidil despite no noticeable results and is exploring other treatments like RU58841.

      community Give me courage, friends! / Is finasteride response correlated with aggressiveness of hair loss?

      in Finasteride/Dutasteride  6 upvotes 3 years ago
      The user has been using topical finasteride for seven months and minoxidil for three years, with added tretinoin gel for ten months, and is experiencing continuous shedding without signs of regrowth. They are questioning if the amount of shedding is normal at this stage of treatment and if there's a correlation between finasteride response and the rate of hair loss.

      community Is it ok to use minoxidil and other topicals simultaneously?

      in Minoxidil  2 upvotes 2 years ago
      The conversation is about whether it's safe to use minoxidil with a mix of stemoxydine, RU58841, alfatradiol, and tretinoin at the same time for hair loss treatment. Concerns were raised about the absorption and effectiveness when these treatments are applied together.

      community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

      in Chat  8 upvotes 5 years ago
      The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community What about azelaic acid, retinol and caffeine, all topical?

      in Minoxidil  7 upvotes 4 years ago
      The conversation is about a user inquiring about a hair loss treatment product that contains minoxidil, azelaic acid, retinol, and caffeine, and whether it is more effective than Regaine foam. No specific treatments or outcomes are discussed.

      community Month 2.5 redo. Topical fin/min microneedling once a week.

      in Progress Pictures  18 upvotes 2 years ago
      A user who initially had positive results with oral finasteride, topical minoxidil, and microneedling for hair loss, but experienced side effects like fog and depression. After stopping and losing progress, they restarted with topical treatments and microneedling, reporting good results and no side effects.