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      community Creatine effects on DHT Experiment

      in Research/Science  58 upvotes 2 years ago
      Creatine might increase hair loss due to increased DHT sensitivity, but evidence is mostly anecdotal. The user is using oral minoxidil for hair loss and is cautious about starting creatine.

      community Taking cordyceps while on dutasteride?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The conversation discusses concerns about using cordyceps while on dutasteride due to potential DHT increase, with OP experiencing hair loss after using creatine. OP is advised to stop creatine and give dutasteride more time to evaluate its effectiveness.

      community Has anyone used Magnesium L-Threonate ?

       70 upvotes 7 years ago
      Magnesium L-Threonate may help treat balding by reducing DKK-1 expression without affecting DHT. Users discuss its potential effectiveness and application methods, with some considering trying it topically.

      community Has my Ru58841 attained degradation?

      in Research/Science 1 year ago
      RU58841 may still be potent after being left unopened for four months if protected from light and air. A user reported hair improvement using RU58841 with minoxidil, without major shedding, over 2.5 years.

      community Thinking about using PP405 and RU58841

      in Research/Science  1 upvotes 5 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community Triple Hair TH-16 released. Thoughts and opinions?

      in Product  33 upvotes 4 years ago
      Triple Hair's TH-16, a product claimed to be more effective than Minoxidil 5%, has been released; it contains melatonin and resveratrol. One user reported success with topical melatonin and dermarolling.

      community Lab results from actifolic RU58841

      in Product  39 upvotes 2 years ago
      The post discusses the user's experience with hair loss treatment RU58841, which was tested for quality and found to be 96+% pure. The conversation includes various responses, with some users questioning the safety of the product and others expressing satisfaction with the test results.

      community Vitamin D3 hair full regrowth?

      in Is this regrowth?  6 upvotes 2 years ago
      A user reported no success with Minoxidil after a year but observed good regrowth after taking 5000 IU of vitamin D3 daily for 2.5 months. They are seeking opinions on whether they will see full regrowth and if others have had similar experiences.

      community who in here has used ru58841 , and how did it go

      in Treatment  8 upvotes 5 months ago
      RU58841 had mixed results for hair regrowth, with some users experiencing no change and others noting regrowth but also side effects like libido issues and chest pain. Some users combined it with other treatments like finasteride and dutasteride, with varying effectiveness.

      community Minoxidil Response Test kit in the EU?

      in Minoxidil  2 upvotes 3 years ago
      A user is seeking a Minoxidil Response Test kit in the EU without bundled consultations. They mention alternatives like oral minoxidil and tretinoin but prefer the test alone.

      community Vitamin D help? Any help would be appreciated :D

      in Chat  55 upvotes 5 years ago
      The individual is experiencing hair loss and has a vitamin D deficiency, with levels at 7.49ng/ml or 26nmol/l. They are unsure if the deficiency is causing the hair loss and are seeking advice on vitamin D supplementation.

      community hello

       144 upvotes 7 years ago
      A 12-year-old diagnosed with alopecia shares their experience and current treatments, including Dermovate, an unnamed cream, and liquid iron. The community offers support and encouragement.

      community Stemoxydine- lifelong use? curious.

      in Treatment  5 upvotes 2 years ago
      The conversation discusses whether stemoxydine needs to be used for life for hair loss treatment. One user suggests that stemoxydine does not require lifelong use and can make hair exit the resting phase faster, but the benefits may be temporary.

      community 5 year recovery while using steroids

      in Update  10 upvotes 1 year ago
      The user shared their 5-year hair recovery journey using finasteride, RU58841, dutasteride, minoxidil, and microneedling, noting mixed progress but overall improvement. They regret not starting treatment earlier and recently received positive health feedback from their doctor.

      community Vitamin D3 Supplement for Hair

      in Chat  6 upvotes 2 years ago
      The conversation discusses recommendations for Vitamin D3 supplements for hair health. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Foods with sufficient procyanidin b2?

      in Treatment  5 upvotes 5 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Conversation focuses on foods with sufficient procyanidin b2, such as dark chocolate and apples, and the required dosage.

      community Help labing up hair preservations

      in Research/Science 1 year ago
      The conversation is about making RU58841 solutions for hair loss treatment and sourcing ingredients for KB solutions. The user mentions using RU58841 powder from Shaanxi Greenyobiotech.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Once daily topical Min, weekly 1.5 mm dermarolling

      in Progress Pictures  35 upvotes 2 years ago
      The user has been using 5% minoxidil once daily and microneedling with a 1.5 mm dermaroller weekly for three months, considering increasing minoxidil usage but avoiding finasteride due to libido concerns. Another person suggests considering other treatments like RU58841, alfatradiol, topical finasteride, clascoterone, or saw palmetto since not using a DHT blocker could be less effective.