The conversation discusses switching from RU58841 to pyrilutamide for hair loss treatment, with users generally recommending staying on RU58841 if it is effective. RU58841 is sourced from GeneTherica, which ships worldwide.
A 25-year-old user shared progress pictures after using oral finasteride and oral minoxidil for nearly four months, reporting significant crown gains and slight temple progress without side effects. The user chews a Hims 3-in-1 tablet and has not experienced any shedding due to starting with a shaved head.
The user has been using finasteride and minoxidil for hair loss but experienced worsening temple recession. They suspect they might be more sensitive to testosterone and are considering trying RU58841 or CB 03 01 as additional treatments.
Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.
The user is experiencing diffuse thinning and has tried treatments like topical and oral finasteride, oral dutasteride, topical minoxidil, microneedling, melatonin, and caffeine without success. Despite using these treatments for over four years, the user reports continued hair thinning and is considering trying RU58841.
Pyrilutamide, a drug in phase 3 trials in China, potentially becoming available in late 2023 or early 2024; Finasteride being used as a current treatment for hair loss; and the possibility of joining a group buy for black market versions of Pyrilutamide.
The user "NotYourMothersDildo" shared their progress pictures after using finasteride and oral minoxidil for 60 days. They noticed significant improvements in hair thickness, texture, and growth, including their mustache and beard.
The conversation discusses using zinc sulphate and azelaic acid to inhibit 5 alpha-reductase activity, which could potentially treat androgen-related skin conditions like hair loss. Combining these with vitamin B6 could enhance the effect, potentially offering an alternative to finasteride.
The user experienced significant hair regrowth using finasteride, minoxidil, and microneedling but later faced rapid thinning despite consistent treatment. They plan to switch from finasteride to dutasteride and consider oral minoxidil if the situation doesn't improve.
RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.
A user shared their 3-month progress using oral finasteride, topical minoxidil, and dermarolling for hair loss. Other users commented on the impressive results and asked questions about the treatments.
PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.
The user cannot handle Minoxidil and is looking for an alternative to dilute topical finasteride. They are considering using Alpecin liquid as a solution.
The conversation discusses concerns about the efficacy of pyrilutamide if left in a mailbox for several hours. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.
A poem humorously suggests hope for a new hair loss treatment, PP405, while users debate the effectiveness and side effects of current treatments like Finasteride. Concerns are raised about Finasteride's side effects, especially for young users, and skepticism about new treatments is expressed.
A 23-year-old shared their positive 4-month progress using 1mg oral finasteride and topical minoxidil for hair loss, noting increased hair health and confidence despite initial shedding. Other users shared similar experiences and results, with some using Kirkland Costco minoxidil.
The conversation discusses hair loss treatments, focusing on the use of Minoxidil, finasteride, and triamcinolone. Concerns are raised about high concentrations of Minoxidil and the long-term use of corticosteroids.
AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.
A user experiencing side effects from a 5% minoxidil and 0.1% finasteride topical solution for hair loss reduced their dosage due to numbness and pain in the lower body and is seeking advice on dosage and alternatives like redensyl. They are concerned about the side effects of both medications and are considering adjusting the dose or switching treatments.
The user is considering reducing RU58841 dosage from 100mg to 17.5mg for long-term safety due to brain fog issues from finasteride. They apply RU58841 only to the front of the scalp where thinning occurs.
The user used topical finasteride 0.3% and minoxidil 6% nightly for 6 months, then added oral finasteride 1mg daily a month ago, which improved hair density. They also started using Flakes shampoo for scalp irritation, finding it more effective than keto shampoo.
A 28-year-old user shared their positive experience with hair loss treatment using 1mg oral finasteride daily, topical minoxidil nightly, and weekly dermapen sessions. They reported increased confidence despite minor side effects like dandruff and gray hair.
Pyrilutamide/KX-826 is being discussed for its effectiveness in hair regrowth, with some users reporting positive results, especially in early hair loss cases. Users have combined it with treatments like Minoxidil, and some experienced initial shedding before seeing regrowth.
Avixis Alfatradiol is a topical 5-alpha reductase inhibitor available in Latin America and Germany, but its effectiveness is questioned. A user reported worsened hair loss after using it and recommended finasteride instead due to its proven effectiveness and lower cost.
Oral minoxidil has shown positive results for hair regrowth, but concerns about its side effects, such as heart issues, are noted. Adding a DHT blocker like finasteride is recommended for better and more lasting results.
Minoxidil use may worsen seborrheic dermatitis, causing itching and dandruff. Users consider stopping minoxidil or switching to foam to improve scalp condition.
The user experienced side effects like shallow breathing, loss of libido, and erectile issues after using topical finasteride with minoxidil for hair loss. They are considering whether to continue the treatment despite these side effects.
A user has used finasteride for three years to maintain hair thickness and is considering adding minoxidil for temple recession. They report no side effects and are satisfied, while others discuss minoxidil's pros and cons and share hair treatment experiences.
The user is using finasteride (1 mg daily), topical minoxidil, and microneedling with a derma stamp for hair loss. They reported shedding stopped and new hair growth appeared after a few months, with no side effects.