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    Did you mean Endoplasmic Reticulum?
    GlossaryEndoplasmic Reticulum

    network of membranes in cells for protein and lipid synthesis

    The Endoplasmic Reticulum (ER) is a network of membranes within a cell that plays a crucial role in the synthesis, folding, modification, and transport of proteins and lipids. There are two types: Rough ER, which is studded with ribosomes and primarily involved in protein synthesis, and Smooth ER, which lacks ribosomes and is involved in lipid synthesis and detoxification processes.

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      community Had a rough week. What to do now?

      in Treatment  36 upvotes 1 year ago
      The user had a rough week after being told they couldn't get a hair transplant due to insufficient donor area and worsening balding. They were advised to increase their oral Minoxidil dosage and consider switching from Finasteride to Dutasteride.

      community Finally decided to post / Started June 26th

      in Progress Pictures  11 upvotes 2 years ago
      The user started hair loss treatment on June 26th using 1.25mg finasteride, 1ml 5% minoxidil twice a day, derma rolling every 1.5 weeks, and 2% ketoconazole foam twice a week. They experienced significant hair growth in the first four months, with thicker hair and improved hairline, but had a rough shedding phase in November.

      community My experience with Alfatradiol so far

      in Treatment  10 upvotes 3 years ago
      User is 16, experiencing hair loss, and using minoxidil and alfatradiol. Shedding decreased, new hairs growing on temples, but unsure if alfatradiol is effective or if future shedding will occur.

      community I am fed up, tired and really need your opinion/help.

      in Minoxidil  13 upvotes 4 years ago
      A person experiencing hair loss is using finasteride and considering minoxidil but is worried about side effects like heart palpitations. They seek advice on continuing minoxidil, trying alternatives like microneedling, or considering a hair transplant.

      community Shedding vitamin levels reminder

      in Treatment  9 upvotes 2 weeks ago
      Addressing hair loss by checking vitamin D and iron levels is crucial before adding more treatments. Supplementing these deficiencies can significantly reduce shedding.

      community Making the jump to hair systems

      in Hair Systems  29 upvotes 4 years ago
      19-year-old with Lichen Planopilaris tried various treatments unsuccessfully. Now considering hair systems, seeking experiences and opinions.

      community Getting hit hard by the shed….

      in Progress Pictures  88 upvotes 1 year ago
      A user is experiencing significant hair shedding after starting a treatment regimen of 1mg oral finasteride, 3mg oral minoxidil, 2.5mg biotin, and vitamins. Despite the shedding, they remain optimistic and plan to continue the treatment for a year before making any conclusions.

      community 3 Months of 2.5 minoxidil + 1mg finasteride

      in Progress Pictures  38 upvotes 1 year ago
      User reports hair improvement after 3 months using 2.5% minoxidil, 1mg finasteride, weekly Nizoral, bi-weekly microneedling, and nightly rosemary oil. Shedding has decreased, and no significant side effects were noted.

      community This guy claims stem cells fixed his balding

      in Is this regrowth?  325 upvotes 2 years ago
      A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

      community How is it looking? 1 mg Fin & 5 mg Min

      in Is this regrowth?  79 upvotes 1 month ago
      The user is experiencing progress in hair regrowth using 1 mg finasteride and 5 mg minoxidil, with no side effects reported. There is a discussion about whether to switch from finasteride to dutasteride, but many advise against it since finasteride is showing good results.

      community 1 year on fin 1mg and top. min. journey

      in Is this regrowth?  9 upvotes 1 month ago
      The user has been using topical minoxidil and oral finasteride for a year, experiencing initial side effects and shedding, but later noticing thicker hair. They are concerned about recent hair loss and considering increasing finasteride dosage, while others suggest patience and possibly adding minoxidil or dutasteride.

      community 1 year vs 2 years on 1mg Finasteride [29M]

      in Progress Pictures  16 upvotes 4 months ago
      The user has been on 1mg finasteride daily for two years, experiencing initial shedding and some hairline recession, with limited regrowth. Suggestions include using oral minoxidil, switching to dutasteride, or considering a hair transplant for better results.

      community Crown Christmas Miracle: Back From the Dead 💀

      in Progress Pictures  2109 upvotes 5 months ago
      A 42-year-old man achieved significant hair regrowth in seven months using oral minoxidil, oral dutasteride, topical minoxidil, microneedling, and supplements. He experienced minimal side effects and noted dramatic improvements in hair thickness and health.

      community 1 year on Finasteride and Minoxidil

      in Progress Pictures  245 upvotes 6 months ago
      The user shared their one-year progress using finasteride and foam minoxidil for hair loss, experiencing positive results with minimal side effects. They are considering a hair transplant for better coverage in the future.

      community Hairline slowly coming back from the dead 💀

      in Is this regrowth?  508 upvotes 7 months ago
      A user experienced positive hair regrowth using oral and topical minoxidil, oral dutasteride, microneedling, and supplements. They noted improved hairline and temple density with minor side effects like a few forehead pimples.

      community How obvious is it that I am using hair fibers to thicken my hairline?

      in Product  175 upvotes 7 months ago
      The user uses Toppik hair fibers to thicken their hairline and has switched from finasteride to dutasteride and oral minoxidil, noticing more hair thickening. Most responses indicate the hair fibers are not noticeable, and many suggest the user doesn't need them as their hair looks natural and good for their age.

      community On the big 6 but very slow , needs acceleration

      in Is this regrowth?  30 upvotes 11 months ago
      The user is using a hair regrowth protocol including dutasteride, topical and oral minoxidil, dermarolling, ketoconazole shampoo, and tretinoin, but is experiencing slow progress and seeks advice for faster regrowth. Suggestions include quitting smoking, adjusting the regimen, and considering additional treatments like topical finasteride or RU58841.

      community Fluridil degrades the androgen receptor.

      in Research/Science  12 upvotes 11 months ago
      Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

      community From Balding Crown to Full Coverage – My Real Progress with a Combined Protocol (But One Big Question About the Hairline)

      in Progress Pictures  101 upvotes 1 year ago
      The user shared their successful hair regrowth using oral finasteride, minoxidil foam, a custom topical solution, ketoconazole shampoo, and microneedling, resulting in significant improvement at the crown. However, they experienced hairline recession after switching to a topical solution with finasteride and minoxidil, raising concerns about its effectiveness.

      community Woke up with the urge to cut all of it off

      in Shaved/buzzed  31 upvotes 1 year ago
      A user decided to buzz their thinning hair after starting Dutasteride, feeling liberated by the change. Other users shared similar experiences, with some using treatments like Finasteride and Minoxidil to manage hair loss.