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      community ET-02 Now Recruiting in Texas for Phase 1

      in Research/Science  20 upvotes 1 year ago
      Eirion Therapeutics is recruiting for phase 1 of ET-02 in Texas, which showed promising hair growth results in non-clinical studies. ET-02 demonstrated significantly more hair growth compared to Minoxidil.

      community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

      in Research/Science  4 upvotes 2 years ago
      The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  447 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Anyone tried switching from RU to Pyrilutamide (KX-826)

      in Product  7 upvotes 3 months ago
      The conversation discusses switching from RU58841 to pyrilutamide for hair loss treatment, with users generally recommending staying on RU58841 if it is effective. RU58841 is sourced from GeneTherica, which ships worldwide.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 3 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community Progress finally (?) 4 months left & right temple

      in Is this regrowth?  38 upvotes 1 month ago
      The user has been using finasteride for two years without results and recently started a new routine involving derma stamping, retinol, and minoxidil, which seems to show progress. The user microneedles about half the week and uses L’Oréal night serum for retinol.

      community Tressless When They See Verteporfin Results

      in Transplants  183 upvotes 2 years ago
      The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.

      community Binding affinity of pyrilutamide!

      in Update  169 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community RU58841 Users: How chemically unstable is RU58841 in practice?

      in Technology  2 upvotes 7 months ago
      The conversation discusses using RU58841 mixed with topical minoxidil for hair loss, noting its chemical instability and storage challenges. A user shares their experience using RU58841 with ethanol and propylene glycol, mentioning no significant results yet.

      community If I can’t tolerate 5ari, should I try Pyrilutamide 1%?

      in Treatment  5 upvotes 10 months ago
      The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alpha reductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.

      community Pyrilutamide 4 Month Journey with progress Pics..!!!

      in Progress Pictures  21 upvotes 8 months ago
      The user reported significant hair regrowth and stopped hair loss after using Pyrilutamide and Minoxidil for four months. They found Pyrilutamide effective in blocking DHT locally without side effects, preferring a gray market version over Koshine's product.

      community So is this the actual trial results for pp405?????

      in Research/Science  93 upvotes 2 weeks ago
      PP405 shows promising results for hair growth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.

      community Anagenic Pyrilutamid, has anyone tried this?

      in Product  2 upvotes 2 years ago
      The conversation is about personal experiences with Anagenic Pyrilutamid for hair loss and what carriers people use with it. No specific treatments or outcomes are mentioned.

      community Would you guys be interested in a pure cb-03-01 progress pick series?

      in Research  71 upvotes 6 years ago
      The conversation is about someone planning to use cb-03-01 for hair loss because they experience side effects with other treatments like finasteride, minoxidil, and RU58841. They have not found progress pictures online and are considering sharing their own experience with cb-03-01, which is expensive.

      community GT20029 - Promising phase II results

      in Research/Science  16 upvotes 1 year ago
      GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

      community Has pyrilutamide worked for anybody?

      in Product  1 upvotes 1 year ago
      The post discusses the effectiveness of pyrilutamide for hair loss. The user maintains hair with alfatrodial, fluridil, minoxidil, and keto shampoo but is seeking a simpler and cheaper alternative.

      community Best carrier for pyrilutamide?

      in Update  9 upvotes 3 years ago
      The conversation is about adding a low dose of pyrilutamide to a hair loss treatment regimen. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Perfect dermaroller routine

      in Advice  6 upvotes 6 years ago
      The conversation is about using a 1mm derma roller for hair loss treatment, including cleaning the scalp with isopropyl alcohol and using castor oil mixed with coconut or olive oil afterward. The user seeks advice on the routine and mentions expected gains.

      community Update on PP405 Trails - Pelage

      in Research/Science  14 upvotes 2 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.