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GlossaryRUNX1

regulates gene expression crucial for blood cell development

RUNX1, also known as Runt-related transcription factor 1, is a gene that plays a crucial role in the regulation of gene expression during the development of blood cells. Mutations in RUNX1 are associated with various blood disorders, including acute myeloid leukemia (AML), making it a significant focus in both clinical and research settings.

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community Ruxolitinib - Start of a case study

in Research/Science 10 upvotes 1 year ago

The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

community Hives/Rash from Kx 826 Pyrilutamide???

in Chat 1 upvotes 1 year ago

OP developed hives after using Kx 826 (Pyrilutamide) 1% twice daily for 3 weeks. The hives appeared on the arms, chest, and groin area.

community To everyone who cant use FIN and doesnt want to use RU

in Treatment 33 upvotes 1 year ago

A new hair loss treatment, KX-826, is being discussed as a stronger and safer alternative to RU58841 and finasteride. Opinions are mixed, with some users skeptical about its effectiveness and others considering it as part of their regimen.

community Kintor KX -826 Pyrilutamide Adds 1 Year Phase 3 Trial For Safety

in Technology 57 upvotes 2 years ago

KX-826/pyrilutamide is undergoing an additional one-year safety and efficacy trial in China after a six-month study. Some participants speculate on the reasons for the extended trial and discuss the potential of other treatments.

community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

in Treatment 22 upvotes 2 years ago

Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

community Ru with gloves because of Systemic absorption?

in Research/Science 10 upvotes 2 years ago

The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.

community Just a little update. RU, minox, and Dut

in Progress Pictures 1077 upvotes 3 years ago

User discusses hair regrowth using RU58841, minoxidil, and dutasteride. Many users praise the progress and ask about the treatments' effectiveness and side effects.

community Has anyone figured out what causes the cardiovascular issues with RU?

in Chat 4 upvotes 11 months ago

RU58841 and Minoxidil can cause heart-related side effects like chest pain and heart racing. Pyrilutamide is suggested as a safer alternative, though it's new and costly.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 52 upvotes 2 years ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community Can mixing RU with min compounded with tretinoin cause the RU to go sytemic

in Chat 3 upvotes 3 months ago

Mixing RU58841 with minoxidil compounded with tretinoin is discussed, with concerns about systemic absorption. Topical dutasteride and finasteride are also mentioned as treatments, with varying personal experiences and concerns about side effects.

community Serioxyl - stemoxydine - not containing stemoxydine in ingredients??

in Product 3 upvotes 1 year ago

The conversation is about a product called Serioxyl, which was expected to contain stemoxydine. It clarifies that Diethyl lutidinate is another name for stemoxydine.

community Pyrilutamide / KX-826 | Discussion EU

in Research/Science 5 upvotes 2 years ago

The conversation is about a user expressing concerns over the safety of a new drug called Pyrilutamide (also known as KX-826) for hair loss. The user will only trust the drug if it's permitted by EU regulations and sold by a reputable company.

community day 107 of kx826 .5% . 1+ years on topical minoxidil.

in Progress Pictures 18 upvotes 1 year ago

The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.

community Anyone wanna try and interview the developers of RU?

in Research/Science 83 upvotes 4 years ago

The conversation discusses arranging an interview with the developers of RU58841 to clarify its safety and reasons for halted research, with some users expressing concerns about potential risks and others citing financial reasons for the discontinuation of studies. Specific treatments mentioned include RU58841, minoxidil, and finasteride.

community KX826 is better than RU58841. A legitimate option for those who cant use fin or dut.

in Research/Science 4 upvotes 2 weeks ago

KX826 is considered a legitimate option for those who cannot use finasteride or dutasteride, but many users report it as ineffective compared to RU58841. RU58841 is favored by some due to anecdotal evidence of effectiveness, despite the lack of published clinical data.

community Rejux-3x - the copper peptide combo that tressless overlooks.

in Research/Science 3 weeks ago

Rejuv-3X, a topical blend with GHK-Cu, AHK-Cu, and JXL-089, is used for hair loss, offering a targeted option without finasteride's side effects. The user plans to combine it with microneedling for enhanced results.

community RU58841 users — how do you find a reliable source?

in Research/Science 2 upvotes 7 months ago

Users discuss finding reliable sources for RU58841, focusing on lab tests, batch consistency, and community reputation. Some mention using alternatives like pyrilutamide.

community Any word from the dudes in the first pyrilutamide Kx group buys?

in Research/Science 18 upvotes 4 years ago

Hair loss discussion includes Minoxidil, Finasteride, and RU58841 treatments. Users inquire about experiences with Pyrilutamide Kx group buys.

community RU + Oral Minox / DUT + Topical Minox

in Progress Pictures 35 upvotes 2 years ago

The individual has been using minoxidil for beard growth for over two years, started oral minoxidil and dutasteride six months ago, and began RU58841 three months ago, which significantly enhanced their results. They are open to answering questions about their hair loss treatment experience.

community pyrilutamide log from someone who couldnt take fin/min/ru due to sideeffects

in Progress Pictures 101 upvotes 3 years ago

A user (seblt) who has had side effects from finasteride, minoxidil and RU58841 but is now trying pyrilutamide as a last resort, with other users providing advice and support. They have already seen some baby hairs growing after 10-14 days of treatment and will provide updates in 1-2 weeks.

community RU58841 powder from lab supplier tested at free drug testing service.

in Research/Science 8 upvotes 1 year ago

Two Chinese suppliers provided legitimate RU58841, confirmed through a free drug testing service. The vendors were Shaanxi Greenyo Biotech and Lyphar, found on Made-in-China.

community Ruderma for maintenance

in Treatments 85 upvotes 10 months ago

The user is considering using Ruderma to maintain hair and is concerned about potential hair loss acceleration due to starting TRT. They are also inquiring about the use of minoxidil, RU58841, and a derma roller for hair maintenance.

community KX-826 Pyrilutamide1% coming soon

in Update 152 upvotes 1 year ago

KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

community Ru-58841 vs KX-826/pyrilutamide while on steroids

in Finasteride/Dutasteride 5 upvotes 1 year ago

The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

community Does RU58841 potentially cause cancer?

in Research/Science 10 months ago

RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.

community Research behind RU-58642? Has anyone heard of this?

in Research/Science 1 upvotes 10 months ago

RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.

community KX-826 , a small change in the pipeline

in Research/Science 6 upvotes 2 months ago

KX-826 is undergoing trials for hair loss treatment, showing similar effectiveness between 0.5% and 1.0% dosages, with mild side effects compared to finasteride. Users discuss combining KX-826 with other treatments like minoxidil and clascoterone for better results.

community What’s more reliable right now, pyrilutamide or RU?

in Treatment 15 upvotes 3 years ago

Treatments for hair loss, with the user considering Pyrilutamide and RU58841 as options. It is noted that although Pyrilutamide has been studied more and is allegedly more effective, there are doubts about its authenticity in the market. KX-826 is suggested as an alternative as it has a stronger effect than RU58841 and there is scientific research on it.

community kx826 .05% month 8 | topical minoxidil .5% month 21 combo update.

in Progress Pictures 6 upvotes 1 year ago

The user used finasteride but stopped due to side effects, then used topical minoxidil for 13 months, and later added KX826/pyrilutamide for 8 months. They experienced shedding after starting pyrilutamide and use minoxidil and KX826 once daily.

community RU-58441 Janoshik test result of Made-In-China Supplier

in Product 30 upvotes 4 months ago

A user ordered RU58841 from a Chinese supplier, found it to be less than 99% pure, and plans to try a different seller next time. Concerns were raised about impurities, but the user believes they are likely inactive fillers rather than harmful substances.