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      community Losing my youthful look: Enjoying it while it lasts

      in Chat  38 upvotes 8 months ago
      The conversation discusses hair loss treatments, focusing on the use of finasteride (fin) and minoxidil (min), with some users recommending dutasteride (dut) for stronger results. Many users emphasize that these treatments are affordable and effective, with some sharing personal experiences of hair regrowth and side effects.

      community How many of you guys have taken accutane?

      in Chat  8 upvotes 1 year ago
      Accutane may accelerate hair loss in genetically predisposed individuals by affecting enzymes related to DHT metabolism. Some users report hair loss after taking Accutane, while others use treatments like finasteride and minoxidil to manage hair loss.

      community 26 , hairloss general questions

      in Is this regrowth?  14 upvotes 1 year ago
      The user has been using finasteride, minoxidil, and Nizoral for hair loss but is not seeing much regrowth. Suggestions include trying oral minoxidil with dutasteride, and some users believe the hair looks better in recent pictures.

      community Diffuse Thinners: When to add to stack?

      in Finasteride/Dutasteride  8 upvotes 1 year ago
      A user experiencing diffuse thinning at the hairline after 12 months on finasteride is considering adding minoxidil, dutasteride, or RU58841 to their treatment. Another user suggests adding minoxidil now, holding off on dutasteride, and shares personal side effects from RU58841.

      community Fin/min was honestly a miracle for me

      in Progress Pictures  436 upvotes 1 year ago
      A user shared progress pictures showing significant hair regrowth after using finasteride and minoxidil for six months. Other users discussed their varied experiences with these treatments and offered additional advice.

      community 5Months 0.5mg Fin + 2.5mg Oral Min | UPDATE #2

      in Progress Pictures  918 upvotes 2 years ago
      The user, Salty-Peace-577, shared their 5-month update on using 0.5mg oral finasteride and 2.5mg oral minoxidil for hair loss. They experienced significant hair growth, particularly in their eyebrows, and shared their regimen and tips for hair growth. Some users in the conversation also discussed the side effects they experienced with different dosages of the medications.

      community This guy is 113 and has more hair than most people on here.

      in Satire  985 upvotes 5 years ago
      A 113 year old man who has more hair than most people, and the conversation is discussing potential genetic factors that may be responsible for this. Possible treatments such as dermarolling and minoxidil, finasteride, and RU58841 are mentioned.

      community find a cure for this shit already

      in Chat  208 upvotes 5 years ago
      Treatments used to prevent and treat male pattern baldness, the difficulty in finding a permanent cure for hair loss, and the potential financial motivations of companies not wanting to find a cure.

      community [Diary] [Day 150?] Dutasteride every day still failing to help

       4 upvotes 9 years ago
      A 22-year-old is experiencing hair thinning despite using finasteride and dutasteride, and plans to try minoxidil next. The user is frustrated with the lack of results and is considering drastic measures if the situation doesn't improve.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  14 upvotes 3 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community RU-58441 Janoshik test result of Made-In-China Supplier

      in Product  27 upvotes 6 months ago
      A user ordered RU58841 from a Chinese supplier, found it to be less than 99% pure, and plans to try a different seller next time. Concerns were raised about impurities, but the user believes they are likely inactive fillers rather than harmful substances.

      community Trialing the probiotics BB536, PTA 6475 so you don’t have to

      in Research/Science  73 upvotes 11 months ago
      Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

      community My summation of PP405 - looks promising

      in Research/Science  206 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community PP405 (Everychem 3HP) users - assemble and share your updates!!

      in Chat  44 upvotes 1 month ago
      Users discussed experiences with Everychem's solution similar to PP405 for hair loss, noting some positive results like increased hair thickness and new growth. There was skepticism about the product's legitimacy and safety, with some users reporting early signs of effectiveness and others expressing concerns about the lack of evidence and safety profiles.

      community PP405 - hair stem cell stimulation

      in Research/Science  53 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community Alpha plus from Anagenica - 25%CB???

      in Product  2 upvotes 2 years ago
      A user ordered Alpha Plus from Anagenica, expecting it to contain specific percentages of Fin, Estradiol, Minoxidil, and CB0301. However, the received product's label showed different percentages, including a surprising 25% CB, leading the user to question its safety and accuracy.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 9 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Pelage Announces Positive Results of Phase 2a Trials for PP405

      in Update  300 upvotes 11 months ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

      community PP405 (Non) Update - Feb 2025

      in Research/Science  34 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community Hy-tissue PRP 50 Experience ??

      in Product  4 upvotes 1 year ago
      PRP treatments have been effective for the user, with a new recommendation of using a high-quality plasma kit once a year. The user seeks experiences with this specific PRP approach.

      community PP405 (Everychem 3HP) Users - Assemble and share your story!

      in Chat  19 upvotes 1 month ago
      Users discussed the effectiveness of Everychem's solution, similar to PP405, with some reporting improved hair thickness and new growth. Concerns were raised about safety and the legitimacy of the product, with some users advising against purchasing research chemicals.