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      community RU58841 and impact onmale fertility?

      in Chat  2 upvotes 1 year ago
      The conversation is about the potential impact of RU58841 on male fertility, specifically regarding sperm concentration, total count, and motility. The user is curious about the likelihood of RU58841 reducing fertility based on its mechanism of action and comparisons to similar substances.

      community Just received my 2 Deoxy D Ribose wish me luck🫡

      in Treatment  243 upvotes 1 year ago
      A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

      community 1 year 5-ar. Blood test results

      in Finasteride/Dutasteride  3 upvotes 10 months ago
      The user experienced sexual side effects after starting finasteride and later switched to dutasteride, noticing hormonal changes. They are considering using P5P and possibly aromatase inhibitors to manage high prolactin and estradiol levels.

      community Can I put pp405 into a dermastamp

      in Microneedling  2 upvotes 8 months ago
      The conversation is about using a dermastamp for hair loss treatment and concerns about a potentially scam product, pp405. It suggests sticking with known treatments like finasteride and minoxidil.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  58 upvotes 2 months ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Which compounds in Saw Palmetto are actually beneficial?

      in Research/Science  3 upvotes 1 year ago
      Saw palmetto's fatty acids, particularly lauric and linoleic acids, inhibit enzymes linked to hair loss, while sterols like beta-sitosterol are less effective due to poor absorption. The conversation questions which specific compounds in saw palmetto contribute to its anti-androgenic effects.

      community Recommend biotin supplement with saw palmetto

      in Product  1 upvotes 6 months ago
      The conversation is about recommending a biotin supplement that includes saw palmetto and possibly copper for hair loss. The user is seeking suggestions for these specific ingredients.

      community The lowest cyproterone dose to stop mpb

      in Treatment  4 upvotes 2 years ago
      The conversation discusses using cyproterone acetate at 12.5 mg to manage hair loss, with concerns about its effects on testosterone and potential health issues. Other treatments mentioned include finasteride, dutasteride, minoxidil, and RU58841, with varying experiences and outcomes.

      community Ultimate Non-5AR (fin/dut) stack?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses alternatives to 5AR inhibitors for hair loss treatment, suggesting options like minoxidil, KX-826, pyrilutimide, microneedling, and topical bicalutamide. Concerns about side effects and the effectiveness of these treatments are also highlighted.

      community New molecule PP405 vs exercise

      in Research/Science  38 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community 1mg Finasteride 4 week Progress

      in Progress Pictures  23 upvotes 2 years ago
      The conversation is about hair regrowth progress after 4 weeks of using 1mg Finasteride, with the user experiencing initial shedding followed by the appearance of small dark hairs on the scalp. Specific treatment mentioned is 1mg Finasteride.

      community 100 days of Fin/Min/Biotin/Saw Palmetto

      in Progress Pictures  398 upvotes 1 year ago
      The user shared impressive hair growth results after 100 days using finasteride, minoxidil, biotin, and saw palmetto, and plans to get a hair transplant. The conversation includes suggestions for additional treatments like ketoconazole and derma stamping, and discussions about potential side effects of finasteride.

      community Is .5% kx-826 worthless? Koshine vs RU

      in Research/Science  3 upvotes 1 year ago
      Kx-826 at 0.5% shows limited effectiveness for hair loss, while 1% is more promising but expensive. RU58841 is considered a more feasible option until 1% kx-826 becomes affordable.

      community Some good news for the future.

      in Research/Science  98 upvotes 1 year ago
      PP-405, a potential hair loss treatment, shows promise in stimulating dormant hair follicles and may help with various hair loss types. Current treatments like Minoxidil are still recommended as PP-405 is in early trials and may take years to become available.

      community Minoxidil Sulfate makes everyone a responder

      in Research/Science  260 upvotes 1 year ago
      Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

      community Creatine and increased MPB Hair Loss

      in Chat  10 upvotes 4 years ago
      Creatine may increase hair loss in those with male pattern baldness (MPB) due to increased DHT, but whey protein generally does not affect hair loss. Finasteride and minoxidil are used to manage hair loss, and some users report increased shedding with creatine but not with whey protein.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community Ru58841 after a hair transplant

      in Transplants  7 upvotes 1 year ago
      A user discussed their hair transplant progress and mentioned using 1mg Finasteride, 5% Topical Minoxidil, and recently starting 5% RU58841. They are seeking advice on whether to use RU58841 at month 4 post-transplant.

      community Will we ever hear about HMI -115

      in Update  20 upvotes 3 years ago
      Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Update on HMI-115 clinical trial expected in July or August.

      community Pyrilutamide Phase 3 on its way

      in Treatment  128 upvotes 4 years ago
      Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

      community Breezula Phase 3 confusion - did they change something?

      in Chat  10 upvotes 4 months ago
      Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.