community Hope Medicine has a new CEO. Calling it now, he's probably going to axe HMI.
Hair loss discussion includes Minoxidil, finasteride, and RU58841 treatments. Hope Medicine has a new CEO, possibly leading to HMI's termination.
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690-720 / 1000+ resultscommunity A hair model who does beauty ads and has 3 million followers claims he went from almost a Norwood 3 to a perfect hairline in 8 months on only Minoxidil and Rosemary oil. Curious, what are people’s thoughts?
This conversation discusses the results of a model who claims he went from almost a Norwood 3 to a perfect hairline in 8 months using only Minoxidil and Rosemary oil. The replies suggest that this could be realistic but long-term results would require additional treatments like finasteride or other medications to prevent further hair loss.
community (1 month pyrilutamide results) what I noticed: massive shedding phase around week 2. it was worse than finasteride and minoxidil shedding. no side effects other than headache the first time I applied it. I feel like it's working but still too soon to tell.
The user experienced significant hair shedding in the second week of using pyrilutamide, more so than with finasteride and minoxidil, and reported a headache after the first application. They believe the treatment may be working but acknowledge it's too early to confirm results.
community Tell me I should be grateful, I’m trying not to shave it off. I’ve had about 2500 graft’s transplanted but I hate seeing my scalp.
A user who had two hair transplants and is still concerned about their crown area, despite other people reassuring them that it looks normal. The advice given was to use Minoxidil, Finasteride, SMP, and to consider speaking with a therapist.
community Anyone here used alfatradiol alone or in their stack and felt it helped? Would like to hear people’s experiences.
Hair loss discussion includes alfatradiol use. People share experiences with alfatradiol and other treatments like Min, Fin, and RU.
community Dermatologist didn’t want to write for Dutasteride and oral minox, instead gave me script for this 12.5% minox with tretinoin,azelaic acid, and topical finasteride. It’s 55$ a month, is it worth it?
The conversation discusses a prescribed hair loss treatment combining 12.5% minoxidil with tretinoin, azelaic acid, and topical finasteride, costing $55 a month. One user criticizes the packaging for degrading tretinoin, another suggests it's an overpriced option and recommends topical dutasteride as an alternative due to its higher molecular weight and lower systemic absorption.
community Don't give up, guys. It might take a little bit of time, but damn it's worth it. Almost 2 years on fin (8 months dut) + topical minox every day, started oral minox few days ago.
User improved hairline with 2 years on finasteride (8 months dutasteride) and daily topical minoxidil, recently started oral minoxidil. No side effects experienced, and user's doctor approved dutasteride for a boost.
community My balding/recovery rollercoaster story so far. I've regrown and lost my hair like 8 times in the last few years. Developed gyno but luckily it's reversible for me. M27
A 27-year-old man experienced hair regrowth and gynecomastia from finasteride, leading to a cycle of stopping and restarting the treatment. He is considering gyno surgery and consulting an endocrinologist as potential solutions.
community Has GT20029 progressed ahead? Any updates on it, as in where it is in it's phases/development? How many years do y'all think it will be till it comes out??
The conversation is about the progress and development of a hair loss treatment called GT20029. People are discussing updates on its status and speculating on how long it will take to become available.
community Thoughts on Pre-Finasteride Bloodwork? Normal/high Total and Free Testosterone, Low DHEA-S?
A 23-year-old male is considering starting Finasteride for hair loss after experiencing persistent shedding and hairline recession, with bloodwork showing normal testosterone levels but low DHEA-S and Vitamin D. He plans to discuss DHEA supplementation with his doctor and has already started Vitamin D supplementation.
community I’ve been using min and nizoral for 7 years, losing a lot of hair in the meantime. Here’s what happened when I added 1mg fin daily and 1.5mm micro needling weekly.
The positive effects of Finasteride, a hair loss treatment; and various other treatments such as Minoxidil and Nizoral that can be used to treat hair loss. Additionally, other methods are discussed, such as micro needling and taking spearmint supplements, which have been seen to help in some cases.
community From the research study: "Dihydrotestosterone and the concept of 5a-reductase inhibition in human benign prostatic hyperplasia" - G. Bartsch, R.S. Rittmaster, H. Klocker (2002) in the "World Journal of Urology".
Dutasteride is a stronger 5AR inhibitor than finasteride and can significantly lower DHT levels. Reduced doses of dutasteride may lower side effects.
community RU 58841, Minox, and Dutasteride 3 times a week. Two months difference. 25 years old. After stopping RU I do believe I lost some of my gains. I think it’s too soon to really get the good effects of DUT.
User shared progress with RU 58841, Minox, and Dutasteride 3 times a week for hair loss. Others noticed improvements and expect great gains over the next year.
community I've been afraid to start Finasteride treatment for 5 years, on it for 2 weeks, regret that hadn't started it earlier and here's my story
A 28-year-old male, losing hair since his teens, started taking 0.31 mg finasteride daily for two weeks with no side effects and regrets not starting earlier. He tried various treatments like minoxidil, scalp massages, and vitamins but found finasteride most effective.
community Anyone else have one chad hair? This thing has somehow held on for dear life for years and years, like an inch past my hairline. Should donate this mf’s follicle to science
Hair loss discussion with a focus on a single resilient hair, jokingly called "chad hair," that remains despite hairline receding. Some users suggest microneedling and hair follicle cloning as potential treatments.
community When I was in my 20s, skinny and with long hair, one of my biggest fear was being fat and bald in my 40s. Now that it’s come to pass, I’ve found there are better things to worry about. I started shaving my head in 05 when I was 32 and I can sum it all up in one word: Liberating.
Accepting hair loss, with solutions discussed including Minoxidil and Finasteride treatments, shaving the head as a liberating experience, and using beards to make up for lack of hair.
community I’m 14 years old and I’m losing more hair than my dad. I’ve gone to the doctor 2 times because of this and I’ve received no help. I’m starting to feel like It’s worthless and my hairs gonna look like this forever. I don’t know how anyone could help me but it’s always worth a shot.
A 14 year old who is experiencing hair loss and has not received any help from the doctor, with advice being given to try different doctors, get tested for underlying conditions and intolerances, buzz it short as an option and treatments that could slow down or reverse the hair loss such as minoxidil, finasteride, RU58841 and addressing the cause of the hair loss.
community Does anybody here know the formula thats basically a weaker version of minox?I know it involves peppermint oil but that's all I can remember
The conversation discusses a natural alternative to Minoxidil for hair loss, with users suggesting peppermint oil and rosemary oil as potential weaker substitutes.
community I received a prescription for DUTASTERIDE CAP 0.5MG and to this day for 7 months I have been taking propecia, I am considering switching because I see that my shedding has not stopped, although I have results that I associate with topical minoxidil. Do they think it's time to move to DUTASTERIDE 0.
A user has been taking Propecia (finasteride) for 7 months and uses topical minoxidil, but is considering switching to dutasteride due to ongoing hair shedding. Another person suggests that 7 months is not enough time to decide on switching medications.
community Start taking care of your skin and hair loss TODAY! I was telling myself I didn’t care, but I think the difference in my facial expression says it all. Take action asap before more permanent damage is done. I hope I can inspire some of you, because it’s so worth it. Not for others, for yourself! <3
User shared progress in treating hair loss and improving skin, using treatments like finasteride, minoxidil, RU58841, tretinoin, microneedling, and skin care regimen. Others commented on the impressive results and asked about costs and side effects.
community Clascoterone full results in July
Clascoterone's full trial results are expected by mid-July 2026, but skepticism exists about timely release. Clascoterone is available at 5% from some telehealth companies.
community European release of clascoterone
Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.
community PP405 (Everychem 3HP) Users, share your story!
Everychem's solution, similar to PP405, has mixed results for hair regrowth, with some users reporting improvements and others seeing no change or worsening hair loss. Users are sharing experiences and updates to determine its effectiveness.
community Clascoterone/ Breezula will it work
Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.
community Pelage have presented only phase 2a. The rest of phase 2 for PP405 will be presented at a later medical meeting
PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.
community Who won’t respond to minoxidil? (Studies)
Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.
community Breezula disappearing like my hair follicles.
Breezula's development has stalled, leaving users disappointed. The conversation includes skepticism about its approval and effectiveness.
community Does This Invalidate PP405 Completely?
PP405's effectiveness in increasing hair density is questioned due to a small sample size, despite investment from Google Ventures. Users express skepticism and suggest waiting for more conclusive results.
community What happened to Scube3? Does somebody know which phase they are right now?
Amplifica's progress on Scube3 is unclear, with no recent updates. The conversation also mentions Minoxidil, finasteride, and RU58841 as hair loss treatments.
community I'm very skeptical about pyrilutamide
Pyrilutamide's effectiveness is questioned due to overstated claims and previous trial ineffectiveness, with some users opting for finasteride instead. Despite skepticism, some consider adding pyrilutamide to their regimen alongside treatments like bicalutamide.