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      community Pyrilutamide 5 months results (before, after pics)

      in Progress Pictures  192 upvotes 3 years ago
      Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.

      community A prayer for our lord and saviour

      in Product  32 upvotes 1 year ago
      The conversation is a humorous and hopeful prayer for the effectiveness of finasteride in combating hair loss. Participants express gratitude and support for the treatment.

      community Hi, I got some regrowth recently and I attribute it to DICLOFENAC

      in Research/Science  8 upvotes 2 years ago
      The user started balding at 16/17 and tried various treatments including minoxidil, finasteride, and dutasteride with little success. They recently started applying diclofenac gel to their bald areas and noticed some hair regrowth, attributing this to diclofenac's ability to lower prolactin levels and its anti-inflammatory effects.

      community Hydrocortisone helps with itch

       4 upvotes 8 years ago
      Hydrocortisone helps relieve scalp itchiness, possibly caused by minoxidil. Users discuss its effectiveness for managing this side effect.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 1 year ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community What has helped you regrow your temples?

      in Chat  21 upvotes 2 years ago
      User seeks advice for regrowing temples, currently using Fin, oral Min, and dermarolling. Suggestions include improving scalp environment and considering RU58841 or dutasteride.

      community What's your thoughts on Pyrilutamide

      in Product  6 upvotes 4 months ago
      The conversation is about using pyrilutamide and RU58841 as topical solutions to prevent hair loss. Pyrilutamide is considered safer but less potent than RU58841, which some users find effective despite potential side effects like heart palpitations.

      community i need your advice please tell

      in Product  2 upvotes 2 years ago
      The user is experiencing stage 2 hair loss and thinning, noticing more scalp visibility with short hair. They are considering diet, yoga, scalp massage, supplements, and a serum recommended by their doctor, and questioning if it's safe to stop using the serum and whether to get a blood test since hair loss isn't a family trait.

      community The Real Reason For Hair Loss?

      in Research/Science 3 months ago
      Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.
      “Mature Hairline” or Genuine AGA?

      community “Mature Hairline” or Genuine AGA?

      in Basic Questions  62 upvotes 1 week ago
      A 33-year-old male is experiencing thinning at the temples and hairline, with increased shedding over the past year. The user suspects androgenetic alopecia (AGA) despite AI suggesting a maturing hairline.

      community Switching from oral to topical dut

      in Finasteride/Dutasteride  1 upvotes 2 months ago
      Switching from oral to topical dutasteride can cause shedding due to changes in DHT levels, and it's recommended to overlap both treatments to minimize this effect. Topical dutasteride may cause scalp irritation, and the user is considering dutasteride mesotherapy as an alternative.

      community Female AGA - Low Cortisol/Low DHEA

      in Female  7 upvotes 3 years ago
      Female (37) experiencing hair loss for 5 years, tried max dose of spiro and oral + topical minox without success. Discovered low cortisol and low DHEA levels, seeking functional medicine practitioner for help.

      community Clascoterone - clearnet vendor

      in Chat  2 upvotes 3 months ago
      The conversation is about finding a clearnet vendor for clascoterone, also known as Winlevi, for hair loss treatment. The user is seeking recommendations via direct message.

      community [M37] 8 months progress with mostly derma rolling and scalp massaging

      in Progress Pictures  621 upvotes 1 year ago
      A 37-year-old male stopped using finasteride and minoxidil due to side effects and switched to derma rolling, scalp massaging, and Revita shampoo, resulting in thicker, healthier hair with new growth. Users discuss the effectiveness of mechanical scalp stimulation, with some sharing similar positive experiences and others expressing skepticism.

      community Suffering from intense sides from dutasteride

       18 upvotes 8 years ago
      A person experienced severe sexual side effects, including loss of libido and erectile dysfunction, after using finasteride and dutasteride for hair loss. They stopped the medications and sought advice, but recovery was slow and uncertain.

      community Breezula by Cassiopea has had a successful Phase II. Apparenlty Phase III trials to start at the end of year. When are we potentially going to be able to get our hands on it?

      in Question  13 upvotes 6 years ago
      The conversation discusses the hair loss treatment Breezula by Cassiopea, which had a successful Phase II trial and is expected to start Phase III by the end of the year. Users are curious about the timeline for availability and note that it performs slightly better than finasteride at 6 months, slightly worse at 12 months, with the benefit of having no side effects.

      community PP405 2a study was a safety study. Some rational explaining.

      in Research/Science  22 upvotes 7 months ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community Recommendations for topical saw palmetto / pumpkin seed oil product

      in Treatment  2 upvotes 5 years ago
      The user is seeking recommendations for topical saw palmetto and pumpkin seed oil products to treat early male pattern baldness and is considering different options available online. They are specifically asking which saw palmetto product to choose between two provided links.

      community Spironolactone for hair loss??

      in Product  6 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and Spironolactone. One user shares success with Finasteride, Minoxidil, and low-dose Cyproterone Acetate, but warns against long-term use of oral anti-androgens.