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      community I spoke to the Guy who did the Ru58841 (PSK-3841) research

      in Research/Science  291 upvotes 5 years ago
      The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

      community Research about RU58841 /Why it was stopped

      in Research/Science  29 upvotes 5 years ago
      RU58841 showed promise for treating androgenic alopecia but research was halted due to financial and organizational changes. There were no significant safety concerns reported in human trials.

      community CB-03-01 supposed hair loss cure

      in Treatment  9 upvotes 5 years ago
      The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

      community So we’re just ok with taking a research chemical now?

      in Treatment  174 upvotes 5 years ago
      The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       22 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community questions regarding topical finasteride

      in Finasteride  4 upvotes 7 years ago
      The conversation discusses the potential effectiveness and risks of using topical finasteride for hair loss, with considerations about using DMSO as a vehicle for application. Concerns are raised about DMSO's safety, absorption issues, and the systemic effects of topical finasteride.

      community Only 10 more days until cassiopea releases their 12 month results for CB-03-01 our best hope of an alternative to finasteride

      in Finasteride  154 upvotes 7 years ago
      The conversation discusses anticipation for CB-03-01, a potential new hair loss treatment that may be more effective and have a cleaner safety profile than finasteride. Users are hopeful but cautious, discussing current treatments like minoxidil, nizoral, and dermarolling, and the possibility of combining them with CB-03-01 for better results.

      community Some Questions Regarding FUE Hair Loss Surgery

      in Transplants  5 upvotes 9 years ago
      The conversation discusses FUE hair transplant surgery, including questions about donor area recovery, success rates, precautions, hair growth rate, and the safety of PRP injections. It also inquires about using hairpieces post-surgery.

      community The mystery of Azelaic Acid

       4 upvotes 11 years ago
      The conversation discusses using Rogaine (Minoxidil) and ketoconazole for hair regrowth, with interest in trying a formulation with Azelaic Acid for potentially better results. Concerns about Azelaic Acid's effectiveness and safety, including skin sensitivity to sunburn, are mentioned.

      community Thinking of making my own Breezula. Any advice?

      in Research/Science  6 upvotes 6 months ago
      OP is considering making a 5% topical Clascoterone (Breezula) for hair loss, as they use Minoxidil but can't use Finasteride due to side effects. They seek advice on creating the topical safely, possibly with help from a trained chemist.

      community Finasteride 1mg daily vs 1.25mg EOD vs 1.25mg 5 days a week

      in Basic Questions  122 upvotes 2 months ago
      The user is treating male pattern baldness with oral minoxidil, ketoconazole, derma rolling, rosemary oil, and topical minoxidil, and is considering adding finasteride. They are debating between three finasteride dosing strategies: 1mg daily, 1.25mg every other day, or 1.25mg five days a week, focusing on efficacy, safety, and cost.

      community Using topicals after hair transplant if safe to do so

      in Transplants  7 upvotes 2 months ago
      After a hair transplant, it's advised to stop using RU58841 and minoxidil to avoid irritation, resuming them 25-30 days post-surgery if the scalp is healed. The user is currently using finasteride, minoxidil, and RU58841, but there are concerns about the safety and efficacy of RU58841 in humans.

      community Dutasteride 5mg progress report

      in Finasteride/Dutasteride  7 upvotes 3 months ago
      A user reports significant hair shedding and regrowth after increasing their dutasteride dosage to 5mg, alongside using RU58841, minoxidil, and topical finasteride, with no side effects. They recommend high doses of dutasteride, sourced from China, despite concerns about its safety.

      community Males 42 years old / 5 months / dutasteride, minoxidil, dermaroller

      in Progress Pictures  128 upvotes 5 months ago
      A 42-year-old male shared his 5-month progress using oral dutasteride, oral and topical minoxidil, and dermarolling for hair regrowth. He reported significant improvement and discussed the potential for further progress and maintenance, while addressing concerns about the safety of his minoxidil dosage.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 5 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Recommendations for topical antiandrogens

      in Treatment  2 upvotes 7 months ago
      The conversation is about adding a topical anti-androgen to a hair loss treatment regimen that includes dutasteride and oral minoxidil. The user is considering topical finasteride or dutasteride, Nizoral shampoo, KX-826, and topical spironolactone, while avoiding RU58841 due to safety concerns.

      community Right way to use Dermapen+Minoxidil

      in General  129 upvotes 7 months ago
      A 43-year-old male from Sydney is seeking advice on using a Dermapen with Minoxidil for hair loss treatment. He inquires about the frequency of Dermapen use, needle depth, cartridge type, timing for applying Minoxidil, safety of numbing cream, and cartridge reuse.

      community Disappointed after dermatologist visit, should I start Finasteride on my own?

      in What should I do?  8 upvotes 8 months ago
      A 19-year-old male is considering starting finasteride on his own for genetic hair loss after a disappointing dermatologist visit, where he was prescribed biotin, ketoconazole shampoo, and saw palmetto instead. Users suggest online options for finasteride and minoxidil, while opinions vary on the effectiveness and safety of saw palmetto and finasteride for someone his age.

      community 2 months in my regrowth journey

      in Progress Pictures  13 upvotes 8 months ago
      The user is using finasteride, topical minoxidil, derma rolling, ketoconazole shampoo, and multivitamins for hair regrowth. They also drink topical minoxidil due to the unavailability of oral minoxidil, despite concerns from others about safety.

      community Progress - 9 months oral minoxidil 2.5 mg & 4 months oral finasteride 1 mg

      in Progress Pictures  8 upvotes 9 months ago
      The user has been using oral minoxidil 2.5 mg for 9 months and oral finasteride 1 mg for 4 months, along with microneedling, and has noticed more baby hairs and longer eyelashes but no extra overall thickness. They are considering increasing the minoxidil dose but are concerned about safety due to potential side effects.