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      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  13 upvotes 2 years ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  7 upvotes 2 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Switch to Oral Minoxidil While Continuing Dutasteride? Need Advice on Next Steps After Accelerated Shedding

      in Progress Pictures  2 upvotes 1 year ago
      The user is experiencing increased hair shedding and is considering switching from a topical solution containing minoxidil, finasteride, and tretinoin to oral minoxidil while continuing oral dutasteride. They are seeking advice on whether this change could improve results and if the recent shedding could be due to a 2-week interruption in dutasteride.

      community Just received my 2 Deoxy D Ribose wish me luck🫡

      in Treatment  243 upvotes 1 year ago
      A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

      community M29 - 4 YEARS on Dutasteride - almost no progress

      in Chat  6 upvotes 5 months ago
      The user has been on a comprehensive hair loss treatment regimen for four years, including Dutasteride, topical and oral Minoxidil, and various other treatments, but has seen little progress and is considering a hair transplant. Despite trying multiple therapies, including PRP and exosome injections, the user is still experiencing hair thinning and is hesitant about trying peptides due to potential cancer risks.

      community A concern regarding the upcoming androgen degrader drug GT20029

      in Chat  11 upvotes 1 year ago
      GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

      community pictures before I started pyrilutamide (repost)

      in Progress Pictures  124 upvotes 3 years ago
      Automatic-Law-3612's progress with hair loss treatments, including topical finasteride, topical dutasteride, minoxidil and pyrilutamide. They have been using these products for two weeks and noticed baby hairs in their temples getting longer.

      community DHT nearly doubled after switching to oral Fin

      in Chat  4 upvotes 3 months ago
      The user switched from topical Minoxidil and Finasteride to oral Finasteride and reduced testosterone, expecting to lower DHT, but instead, DHT increased and hair loss worsened. The user is seeking advice on whether to return to the previous topical treatment or if others have experienced similar issues with oral Finasteride while on TRT.

      community Improvement or Delusional? 21M

      in Is this regrowth?  4 upvotes 1 year ago
      A user is using topical finasteride, keto shampoo, microneedling, and tretinoin for hair loss and is considering adding pyrilutamide. They notice some improvement at the temples and seek advice on whether to focus on cosmetic results despite daily shedding.

      community Possible solution: 2.5mg DUT for everyone

      in Chat  13 upvotes 1 year ago
      A user is experimenting with creating a DIY oral Dutasteride solution using raw powder, MCT oil, and Vitamin E to reduce costs. Others discuss their experiences with similar methods and the challenges of sourcing and testing Dutasteride.

      community Results 2.5 mg dut and miniature hairs.

      in Is this regrowth?  22 upvotes 1 year ago
      The user has been taking 2.5 mg of dutasteride for 6 months and using minoxidil topically for 3 years but hasn't seen significant hair regrowth, only a slight decrease in hair loss. Suggestions include switching to oral minoxidil, adding microneedling, or using growth agonists like bimatoprost to improve results.

      community Are these all vellus hairs that will go terminal?

      in Is this regrowth?  5 upvotes 8 months ago
      The user is using oral minoxidil, ghk-cu, and HGH for hair regrowth, noticing small vellus hairs on the crown. They avoid traditional DHT blockers like finasteride due to side effects, despite skepticism from others about the effectiveness of ghk-cu.

      community Recommend me Shampoo or Saw Palmetto?

      in Chat  1 upvotes 2 years ago
      A 24-year-old male experiencing increased hair thinning and shedding recently started using rosemary and castor oil, microneedling, and an anti-dandruff shampoo. He is considering adding Saw Palmetto and seeks recommendations for a good shampoo.

      community Clascoterone - clearnet vendor

      in Chat  2 upvotes 5 months ago
      The conversation is about finding a clearnet vendor for clascoterone, also known as Winlevi, for hair loss treatment. The user is seeking recommendations via direct message.

      community Month 8 Progress Pics. Think it may be working?..

      in Progress Pictures  93 upvotes 4 months ago
      A user shared their 8-month progress using oral dutasteride and 2.5 mg oral minoxidil daily, reporting improved hair density with minimal side effects, except for a slightly decreased libido. They did not use any supplements but occasionally used a derma stamp.

      community Bicalutamide for hair loss

      in Treatment  4 upvotes 5 years ago
      Bicalutamide is discussed as a treatment for hair loss, particularly in females, with some users cautioning against its use due to potential side effects. The conversation also mentions using finasteride and other anti-androgens, with some users recommending more traditional treatments like dutasteride.

      community Is there a possibility it's only because of the SD

      in Ketoconazole 4 years ago
      A user is experiencing severe hair loss, diagnosed with seborrheic dermatitis, and is using Ketoconazole and beclomethasone. They are concerned about potential female pattern baldness and are seeking reassurance and advice.

      community Severe diffuse thinning after scalp inflammation – should I keep fighting or just accept it?

      in Finasteride/Dutasteride  4 upvotes 8 months ago
      A 23-year-old experiencing severe diffuse thinning after scalp inflammation is considering finasteride as a last resort after stopping minoxidil and using anti-inflammatory medication. Users suggest that inflammation causes temporary shedding and recommend consulting a dermatologist, with some advocating for finasteride as a reliable treatment option.

      community 9 month before and after, dut only

      in Finasteride/Dutasteride  37 upvotes 1 year ago
      The user experienced noticeable hair growth after 9 months using oral dutasteride, with full results expected in 20-24 months. They prefer oral treatments over topical minoxidil due to convenience.

      community PYRILUTAMIDE progress in 15 months

      in Progress Pictures  25 upvotes 2 years ago
      The conversation discusses hair loss treatments, specifically the progress made with Pyrilutamide over 15 months. One person suggests using oral Minoxidil or Dutasteride, but another mentions experiencing negative side effects from oral Finasteride.

      community RU + Oral Minox / DUT + Topical Minox

      in Progress Pictures  35 upvotes 2 years ago
      The individual has been using minoxidil for beard growth for over two years, started oral minoxidil and dutasteride six months ago, and began RU58841 three months ago, which significantly enhanced their results. They are open to answering questions about their hair loss treatment experience.