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GlossarySaponification Value

amount of alkali needed to saponify a fat or oil

The Saponification Value (SV) is a measure of the amount of alkali (usually potassium hydroxide) required to saponify a given quantity of fat or oil. It indicates the average molecular weight (or chain length) of all the fatty acids present. This value is crucial in industries like soap making and cosmetics, as it helps determine the quality and properties of the final product.

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community Can I use wound cleanser to make topical finasteride, it contains 70% IPA and rest Purified Water?

in Finasteride/Dutasteride 4 upvotes 1 year ago

The user wants to make a topical finasteride solution using wound cleanser with 70% IPA and add 40% propylene glycol due to headaches from minoxidil. They seek advice on using the wound cleanser and recommendations for pharmaceutical/cosmetic grade IPA in India.

community Solvent for topical fin with low absorption

in Product 2 upvotes 1 year ago

The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.

community Diluting DIY topical finasteride

in Finasteride/Dutasteride 2 upvotes 7 months ago

A user is discussing making a DIY topical finasteride solution using ingredients like water, alcohol, propylene glycol, ethanol, and glycerin, and is concerned about the stability of the mixture. Other users suggest that the solution will work and discuss the importance of propylene glycol for drug dissolution and factors like temperature and light affecting finasteride stability.

community possible treatment of AGA and change in sebaceous gland condition and oil production using sulfur soap

in Research/Science 4 upvotes 6 months ago

Sulfur soap may help with hair thickening and reducing scalp inflammation, but it can cause dryness. Nizoral, containing ketoconazole, is noted for its potential to reduce seborrheic dermatitis but may also cause scalp dryness and hair loss.

community Homemade Topical Finasteride Formula?

in Treatment 6 upvotes 4 years ago

User wants to make homemade topical finasteride to minimize side effects and asks about using glycerin, stirring time, storage, and alternative solvents. Another user's comment is unclear.

community the post about vitamin c and pH levels is legit.

in Update 12 upvotes 4 years ago

Using vitamin C in shampoo to adjust pH levels can improve hair health and reduce oiliness and dandruff. The user mixed vitamin C powder with conditioner, achieving positive results.

community Making topical finasteride solution

in Finasteride/Dutasteride 1 upvotes 2 years ago

The user has been mixing finasteride with stemoxydine for hair loss and is considering switching to a less expensive product with a different ingredient list. They are questioning if the new product's higher water content compared to alcohol will affect the finasteride's solubility.

community Topical fin formulation question

in Finasteride 91 upvotes 1 year ago

A user is making a homemade topical finasteride solution by dissolving crushed finasteride tablets in ethanol and PG. They are unsure if the final solution maintains the intended concentration after filtering and are considering adding more ethanol to ensure accuracy.

community AttentionHomemade Topical Fin Users- requesting Feedback

in Finasteride/Dutasteride 5 upvotes 1 year ago

A user is seeking feedback on a homemade topical finasteride formula for hair loss, consisting of 7.5 mg of finasteride, propylene glycol, ethanol, and distilled water. They aim to achieve a 0.0125% solution by applying 2 ml daily.

community The best Ethanol/Propylene Glycol ratio for home made topical finasteride?

in Finasteride/Dutasteride 4 upvotes 2 years ago

The conversation discusses the best ethanol and propylene glycol ratio for homemade topical finasteride, with a focus on absorption and drying issues. The user shares their experience using a 50% propylene glycol, 30% ethanol, and 20% water solution, and considers adjusting the ethanol content for better results.

community Effects of 2% vs 5% min for sebderm

in Minoxidil 1 upvotes 1 year ago

Switching from 2% liquid minoxidil to 5% foam minoxidil reduced scalp irritation but increased eyebrow flakiness and thinning. The user speculates that propylene glycol in the liquid formulation might have been protecting against seborrheic dermatitis while causing contact dermatitis.

community Does anyone know the chemical formula for pelage pp405?

in Research/Science 14 upvotes 1 year ago

The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

community Those who make homemade topical fin, what your pg, alcohol amd water percentage?

in Finasteride/Dutasteride 5 upvotes 3 years ago

Homemade topical finasteride solutions are discussed, with one user using 30% ethanol, 50% propylene glycol, and 20% water. Alternatives like dissolving finasteride pills in minoxidil and using stemoxydine are also mentioned.

community The best vehicle/carrier for RU58841

in Treatment 2 upvotes 2 years ago

The conversation is about the best vehicle for RU58841, comparing trichosol and Garnier/Vichy Stemoxydine, avoiding propylene glycol (PG) or ethanol due to previous scalp damage. The user is also seeking sources for these products in the EU.

community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

in Research/Science 4 upvotes 2 months ago

Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

community Sodium Laureth Sulfate (SLS) in shampoos

5 upvotes 10 years ago

Sodium Laureth Sulfate (SLS) in shampoos and its potential impact on thinning hair. The user follows a regimen of shampoo, keto shampoo, and conditioner, seeking suggestions for better products.

community Ru with gloves because of Systemic absorption?

in Research/Science 10 upvotes 2 years ago

The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.

community Mixing Topical Finasteride: isopropyl alcohol / Propylene glycol ratio

in Finasteride/Dutasteride 2 upvotes 7 months ago

The conversation discusses adjusting the isopropyl alcohol, propylene glycol, and water ratios in a topical finasteride solution for better scalp comfort and less dandruff. The user considers using 20ml IPA, 25ml PG, and 15ml water in a 60ml bottle, moving away from mixing finasteride with topical minoxidil.

community I want to prepare a Topical Catalase with Phosphate Buffered Saline Solution.

in Treatment 2 upvotes 2 weeks ago

The conversation discusses creating a topical catalase solution with phosphate buffered saline, glycerin, and polysorbate 20 for hair loss treatment. The user seeks advice on preparing this solution.

community Any red flags in these shampoo ingredients (Davines VOLU)? I only use it about once a week

in Product 1 upvotes 2 years ago

The conversation is about evaluating the ingredients in Davines VOLU shampoo for potential red flags. The user is concerned about which ingredients to avoid despite the shampoo being sulfate-free.

community Topical Finasteride with rogain foam as solvent

in Finasteride/Dutasteride 1 upvotes 4 years ago

The conversation discusses using Rogain foam as a solvent for topical finasteride due to an allergy to propylene glycol. The foam's ingredients, including alcohol SD 40B, are considered suitable for dissolving finasteride for easier application without skin irritation.

community Je peux utiliser ce produit seul comme solvant pour dilluer mon finasteride ?

in Finasteride/Dutasteride 2 weeks ago

OP asked if a product from Amazon is sufficient to dilute finasteride. A user advised against using propylene glycol alone, suggesting a pre-made solution instead.

community Sandalore (Givaudan) concentration application

12 upvotes 7 years ago

The conversation discusses using Sandalore for hair loss treatment, with a focus on finding the correct concentration for a topical lotion. The consensus is to start with a 0.1% concentration due to potential scalp irritation at higher levels.

community Put P5P in my shampoo, reduced itch a lot!

in Chat 4 upvotes 3 years ago

The user added P5P (vitamin B6) to their shampoo to reduce scalp itch, which improved significantly. They have been using finasteride for hair loss but are exploring additional treatments like topical antiandrogens and prolactin inhibitors.

community Money Savings: Foam applicator for regular liquid to save $?

in Minoxidil 43 upvotes 10 months ago

The conversation discusses converting liquid minoxidil into a foam version to save money. The user is exploring if a foam sprayer can achieve this or if additional ingredients are needed.

community Preparing Topical Finasteride with Stemoxydine

in Finasteride/Dutasteride 10 upvotes 5 years ago

Creating a topical solution combining finasteride and stemoxydine to treat hair loss, and the discussion of whether 15mg of finasteride would be sufficient for 60ml solvent.

community thoughts on topical Saw Palmetto oil

in Treatment 4 upvotes 1 year ago

The user is considering topical Saw Palmetto or Pumpkin Seed Oil due to sensitivity to finasteride and cost issues. They also use dermastamping for Minoxidil absorption and seek advice on timing to avoid systemic absorption.

community Solution vehicle used by compounding pharmacy

in Research/Science 1 upvotes 2 years ago

The user is using 0.1% dutasteride, 1% minoxidil with 2% procapil and 0.005% caffeine in the morning, and 1% minoxidil with 2% procapil and 0.01% tretinoin at night. They are concerned about the solution vehicle's effectiveness in preventing systemic absorption and ensuring the products stay around the hair follicles.

community Which compounds in Saw Palmetto are actually beneficial?

in Research/Science 2 upvotes 1 year ago

Saw palmetto's fatty acids, particularly lauric and linoleic acids, inhibit enzymes linked to hair loss, while sterols like beta-sitosterol are less effective due to poor absorption. The conversation questions which specific compounds in saw palmetto contribute to its anti-androgenic effects.

community Sons altering formula, clinically sound or greed?

in Product 6 upvotes 1 month ago

A user is concerned about a change in the formula of Sons topical treatment, which now requires fewer sprays but contains less minoxidil. They question if the change is for convenience or if it's a way to charge the same for less product.