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      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  736 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community only microneedling and supplements

      in Progress Pictures  67 upvotes 7 months ago
      The user used microneedling, zinc, vitamin D3, biotin, magnesium, saw palmetto, pumpkin seed oil, and a DHT-blocker shampoo with biotin for hair loss. They are considering adding minoxidil due to stagnation in progress.

      community Brutal ongoing Shed after 15 months on fin

      in Treatment  7 upvotes 2 years ago
      User is experiencing severe hair loss despite using finasteride for 15 months, losing 500 hairs a day and 50% density since June. Minoxidil with needling was ineffective, and RU58841 is too expensive and hard to obtain.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community Making RU58841 but actually good

      in Chat  3 upvotes 1 year ago
      The conversation discusses creating a foam version of RU58841 for easier application on thick hair, comparing it to minoxidil foam. The user currently uses dutasteride, minoxidil, and needling for hair loss treatment.

      community Best Sources for High Purity Ru58841

      in Product  2 upvotes 5 months ago
      The conversation is about finding high-purity RU58841 solutions for hair loss treatment, with mentions of Anagenic, Selleckchem, MV Supplement, and rudirect.co.uk as potential sources. Users discuss their experiences and preferences regarding product quality and shipping.

      community Microneedling at 1mm feels I'm hitting my skull

      in Microneedling  20 upvotes 1 year ago
      A user discusses their experience with at-home microneedling at 1mm for hair growth, feeling like they're hitting their skull. Other users suggest lowering the needle depth or stopping due to discomfort.

      community Best device for microneedling?

      in Microneedling  9 upvotes 1 year ago
      The conversation is about someone seeking advice on the best microneedling device to use for hair loss, mentioning pens, stamps, and rollers as options.

      community Q1/Q2 Exciting times ahead - hope!

      in Research/Science  16 upvotes 1 year ago
      The conversation discusses various hair loss treatments, including Breezula, KX826, and PP405, with mixed opinions on their effectiveness compared to finasteride and minoxidil. Some users express skepticism about the new treatments, while others remain hopeful about future developments.

      community Novel effect of sildenafil (cialis) on hair growth

      in Research/Science  19 upvotes 3 years ago
      Sildenafil (Viagra) shows potential for hair growth by enhancing dermal papilla cell proliferation and stimulating perifollicular vessel formation. Users discuss the possibility of using Cialis (tadalafil) similarly, noting its benefits and side effects.

      community My Hair System Journey, Part 4

       18 upvotes 6 years ago
      The user shares their experience with a hair system, noting no one noticed the change except their girlfriend. They discuss the learning curve, maintenance tips, and their satisfaction with the results, feeling more confident and optimistic.

      community Which dermaroller do y'all use?

      in Microneedling  26 upvotes 1 year ago
      The conversation is about recommendations for microneedling tools for hair loss, with users suggesting a dermastamp from Koi Beauty and the Derminator 2 with 12-needle cartridges.

      community Good News, PP405 is out on Shopee

      in Product  271 upvotes 1 month ago
      A product called "PP405 Hair Follicle Serum" is being sold on Shopee, claiming to cure baldness without clinical trials or FDA approval, but users are skeptical and refer to it as "snake oil." Some users discuss testing the product's contents, while others share their experiences with hair loss treatments like finasteride.

      community I gotta get this off my chest, i gotta split something

      in Satire  10 upvotes 2 years ago
      The conversation is a satirical expression of frustration over hair loss, mentioning treatments like spironolactone, microneedling, and topical applications, with references to various hair loss products and personalities in the community.

      community Scalp micropigmentation (smp) after 1 year

      in SMP  21 upvotes 1 year ago
      A user shared their experience with scalp micropigmentation (SMP) after one year. They discussed using Minoxidil, finasteride, and RU58841 as treatments for hair loss.

      community I made the ultimate shedding table

      in Satire  122 upvotes 1 year ago
      The conversation humorously discusses hair loss and treatments, specifically finasteride and topical minoxidil, with the OP joking about making art from shed hair. Users engage in light-hearted banter about hair loss and related habits.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 2 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Pyrilutamide application questions

      in Treatment  3 upvotes 2 years ago
      Sprocketshead asks if pyrilutamide can be applied with minoxidil, and inquires about its consistency and odor. They want to know if it's more high maintenance than topical minoxidil.