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      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 2 years ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community This sub is very toxic towards people who don’t blindly follow the fin mafia

      in Treatment  226 upvotes 2 years ago
      The conversation criticizes the negative attitude towards those concerned about side effects from hair loss treatments like finasteride and minoxidil, or who prefer natural remedies. Specific treatments discussed include finasteride, minoxidil, rosemary oil, and RU58841, with an agreement that finasteride and minoxidil are proven effective.

      community Can someone explain the Dutasteride hysteria in this community?

      in Finasteride/Dutasteride  58 upvotes 2 years ago
      The conversation is about the double standard in the hair loss community regarding shedding when using different treatments. The conclusion is that shedding is considered normal when starting finasteride or minoxidil, but not when starting dutasteride, despite the fact that dutasteride is more effective at reducing DHT.

      community Suggest best derma pen in India

      in Microneedling  3 upvotes 10 months ago
      The conversation is about a hair care routine focused on microneedling and using DHI Hair Serum for temple hairline regrowth, without using minoxidil or finasteride. The user seeks advice on the best derma pen in India and feedback on their routine.

      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 1 year ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

      community I’m really tired of using minoxidil

      in Minoxidil  42 upvotes 2 years ago
      The user is frustrated with minoxidil's lack of results and is considering alternatives like oral minoxidil or finasteride despite concerns about side effects. Other suggestions include consulting a doctor, adjusting dosages, or considering a hair transplant.

      community 2 year fin/min progress (age 27-29)

      in Progress Pictures  302 upvotes 2 years ago
      A user's two-year progress using 1mg of oral finasteride daily and twice daily application of 5% minoxidil solution for hair loss. The user experienced temporary side effects but is pleased with the results, and another user warns about the importance of consistent use for maintaining results.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 2 years ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

      community Leaving the fight. Got buzzed.

      in Shaved/buzzed  271 upvotes 2 years ago
      The conclusion of the conversation is that the user has decided to embrace their hair loss and has buzzed their head. They plan to continue their current hair loss treatments until they run out of stock. They also mention having dandruff and will continue medication for that.

      community Body Hair Transplants with Buzzcut

      in Transplants  5 upvotes 2 years ago
      Body hair transplants may look better if kept very short. People with limited donor regions or waiting for Verteporfin or FAK Inhibitors could consider this option.

      community How an SSRI seemed to help my hairloss

      in Chat  5 upvotes 3 years ago
      An SSRI (paroxetine) reduced hair loss and itching for a user with male-pattern baldness, but liver issues forced discontinuation, leading to increased hair loss and anxiety. The user plans to try other anti-anxiety medications, noting stress and anxiety significantly impact hair loss.

      community I saw results in just 10 days ..

      in Minoxidil  6 upvotes 2 weeks ago
      The user reported noticeable hair thickening after 10 days of using oral minoxidil and finasteride, but others suggested it might be an April Fool's joke or a placebo effect. The user also mentioned a high protein intake and regular gym workouts, while others discussed concerns about finasteride's side effects.

      community 8 years of hair loss, turning 30 next month

      in Progress Pictures  151 upvotes 9 months ago
      The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

      community 37/m, 9 months progress, topical 5%min and 6%Fin

      in Progress Pictures  175 upvotes 1 year ago
      A 37-year-old man experienced significant hair regrowth over nine months using a topical solution of 5% Minoxidil and 0.3% Finasteride. He reported no side effects and noted the treatment's effectiveness despite initial dosage confusion.

      community Retin-a (tretinoin) increase effect of minox

      in Minoxidil  27 upvotes 6 years ago
      The conversation discusses how applying topical tretinoin for 5 days can convert 43% of individuals who initially do not respond to minoxidil into responders, enhancing the effect of minoxidil on hair growth. Specific treatments mentioned are minoxidil and tretinoin.

      community Fin/Min/VitD 3 month progress pics

       116 upvotes 7 years ago
      A user shared their positive 3-month experience using finasteride, minoxidil, and vitamin D to treat hair loss, noting significant regrowth and minimal shedding. They also discussed potential side effects and the low likelihood of experiencing them, while being open to answering further questions.

      community Got some bloodwork done, horrifying results.

       9 upvotes 8 years ago
      The user is concerned about high DHT levels despite using finasteride and dutasteride for hair loss, suggesting these treatments may not be effective. They plan to consult an endocrinologist and consider other antiandrogens, acknowledging potential side effects.

      community Almost a year on fin + minox and things are worse - need advice

      in Progress Pictures  4 upvotes 1 week ago
      A user is concerned about worsening hair loss despite using oral finasteride, oral and topical minoxidil, microneedling, keto shampoo, and vitamin D for almost a year. Suggestions include switching to dutasteride, continuing minoxidil, and considering different styling or haircuts.

      community Finasteride/dutasteride todo mal

      in Finasteride/Dutasteride  2 upvotes 2 weeks ago
      The user experienced persistent acne and skin issues with dutasteride, leading them to stop its use. They switched to finasteride, which caused mild acne and potential liver concerns, prompting consideration of alternative treatments like topical finasteride and GHK-Cu.

      community Sule Hair Transplant in Istanbul Turkey | 5000 grafts | 6 months post-op

      in Transplants  30 upvotes 3 weeks ago
      A user shared their 6-month update after a 5000-graft hair transplant at Sule Hair Clinic in Istanbul, noting a smooth procedure and ongoing growth without using finasteride or minoxidil. Some users expressed concerns about the decision to avoid these treatments, predicting potential future hair loss issues.

      community Can I take bicalutamide for hair loss as a man, but don’t want to transition?

      in Treatment  3 upvotes 1 month ago
      A 23-year-old man with hair loss, despite using dutasteride, oral minoxidil, and RU58841, is considering bicalutamide for regrowth but is concerned about feminization. Alternatives like topical estrogen, JXL069, and spironolactone are discussed, with suggestions to explore thyroid levels and other potential underlying conditions.

      community My hair transplant journey in Turkey

      in Transplants  336 upvotes 1 month ago
      A user shared their positive experience with a hair transplant in Turkey using the DHI and Sapphire FUE techniques, without taking finasteride or minoxidil post-surgery. They emphasized that transplanted hairs from the donor area are resistant to hair loss, but acknowledged that native hairs might still thin without medication.

      community European finasteride difference

      in Finasteride/Dutasteride  102 upvotes 1 month ago
      Topical finasteride in Europe is often seen as less effective than oral forms, with users suggesting alternative application methods for better results. Many prefer oral finasteride due to cost and effectiveness.

      community A miraculous drug that regrows body parts.

      in Research/Science  154 upvotes 2 months ago
      A drug that regrows body parts, but not hair, sparking debate on hair loss treatments. Discussions include the use of finasteride, dutasteride, and the potential for new methods to restore hair.

      community 5 months of topical Minoxidil. Don’t give up hope

      in Progress Pictures  311 upvotes 2 months ago
      A user shared their positive experience with topical Minoxidil for hair regrowth, noting thicker and fuller hair without using Finasteride due to concerns about side effects. Many commenters advised adding Finasteride to maintain gains, warning that Minoxidil alone might not prevent future hair loss.

      community The future of hair loss drugs.

      in Research/Science  32 upvotes 2 months ago
      Clascoterone 5% and PP405 are being discussed as potential future treatments for hair loss, with clascoterone nearing phase three completion and PP405 possibly taking a cosmetic route to market. Current treatments like minoxidil, finasteride, and RU58841 are mentioned as effective in slowing hair loss, but a complete cure remains elusive.