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      community HairClone: Good info from their site

      in Technology  10 upvotes 4 years ago
      HairClone aims to rejuvenate miniaturizing hair follicles through follicle banking and cell expansion, with treatments potentially available in the UK by 2022. The process involves extracting, storing, and cloning hair follicles, but full regenerative treatments will take many years to develop.

      community It’s all about the stem cells…

      in Research/Science  52 upvotes 4 years ago
      Hair loss is linked to the loss of stem cells in hair follicles, and potential treatments include gene editing and microneedling. Discussions also mention using Minoxidil, finasteride, and dermarolling to improve hair growth.

      community Good News, PP405 is out on Shopee

      in Product  268 upvotes 2 months ago
      A product called "PP405 Hair Follicle Serum" is being sold on Shopee, claiming to cure baldness without clinical trials or FDA approval, but users are skeptical and refer to it as "snake oil." Some users discuss testing the product's contents, while others share their experiences with hair loss treatments like finasteride.

      community It is kind of diabolical how this works

      in Chat  1568 upvotes 1 month ago
      DHT promotes hair growth in certain areas but causes scalp hair loss, highlighting a frustrating irony. Minoxidil is mentioned as a treatment that grows hair everywhere, including the scalp.

      community How come topical finasteride even works at all?

      in Finasteride/Dutasteride  32 upvotes 5 months ago
      Topical finasteride can effectively reduce scalp DHT by targeting local enzymes, despite less systemic impact compared to oral forms. Combining oral dutasteride with topical finasteride and minoxidil may enhance hair loss prevention, though evidence of its effectiveness is limited.

      community Topical finasteride vs oral Dutasteride?

      in Finasteride/Dutasteride  7 upvotes 7 months ago
      Oral Dutasteride and topical Finasteride may have similar effects on scalp DHT, but topical Dutasteride might be less effective due to poor absorption. Combining oral Dutasteride with topical Finasteride could potentially enhance results by blocking DHT in both the scalp and serum.

      community What Are the Technicalities of Curved Hair Transplantation?

      in Transplants  4 upvotes 3 weeks ago
      Curved hair transplantation requires specialized tools and techniques to avoid damaging hair follicles, with modified FUE being the preferred method. Proper extraction and implantation angles are crucial to prevent complications like keloids and sterile folliculitis.

      community Why dont we research more on body hair

      in Chat  32 upvotes 1 month ago
      Body hair is more resilient than scalp hair due to different gene expressions and DHT sensitivity. Treatments like minoxidil and finasteride are used for hair loss, but they have varying effects on body and scalp hair.

      community Who won’t respond to minoxidil? (Studies)

      in Research/Science  35 upvotes 1 month ago
      Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

      community TCA 35% chemical peel, don't try this shit at home.

      in Treatment  10 upvotes 2 months ago
      The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.

      community Six months 0.5 duta+ 5mg oral mino

      in Is this regrowth?  62 upvotes 2 months ago
      The user experienced hair regrowth and reduced scalp visibility after six months of using 0.5 mg dutasteride and 5 mg oral minoxidil. Suggestions included continuing the treatment, dermarolling with hyaluronic acid, and considering a hair transplant.

      community Story time! The Great Unbalding (PP405)

      in Research/Science  234 upvotes 6 months ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

      community Is fin not working for me? Burning sensation

      in Finasteride/Dutasteride  1 upvotes 9 months ago
      The user is experiencing a burning sensation on their scalp despite using finasteride and nizoral for hair loss, and is unsure if they should switch to dutasteride. They have reduced their testosterone dose but the burning persists, and a trichologist suggested it might be telogen effluvium.

      community Rational Review of Pelage Results

      in Chat  11 upvotes 10 months ago
      A treatment showed a 20% hair density increase in weeks, with nearly a third of participants experiencing significant results, while questions remain about its long-term efficacy and effectiveness across different scalp areas. There is interest in combining it with finasteride and minoxidil for potentially better outcomes.

      community Hair Loss Inflammation Prevention Stack

      in Research/Science  48 upvotes 1 year ago
      The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

      community Did UCLA Just Cure Baldness? Check this Out!

      in Research/Science  968 upvotes 1 year ago
      UCLA's PP405 shows promise in reactivating dormant hair follicles for hair loss treatment but is still in clinical trials. Minoxidil and finasteride remain common treatments until PP405 becomes available.

      community Fun thought experiment about halting hair loss permamently

      in Research/Science  58 upvotes 1 year ago
      A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

      community My experience and hair transformation journey

      in Update  68 upvotes 2 years ago
      The user improved their hair density and reduced scalp visibility by using 1% ketoconazole shampoo, 1mg finasteride, and 5% minoxidil, which increased their confidence. Replies discuss the effects of these treatments, with one clarifying that minoxidil does not affect hormones but finasteride does.

      community An idea that I came up with recently💡

      in Satire  289 upvotes 2 years ago
      User suggests rotating scalp 180 degrees to address hair loss. Others discuss sanity, ethics, and similar procedures like scalp reduction and hair transplants.

      community Put P5P in my shampoo, reduced itch a lot!

      in Chat  4 upvotes 3 years ago
      The user added P5P (vitamin B6) to their shampoo to reduce scalp itch, which improved significantly. They have been using finasteride for hair loss but are exploring additional treatments like topical antiandrogens and prolactin inhibitors.