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The conversation discusses a user's plan to inject NAD+ and GHK-Cu into their scalp to improve hair health, with concerns raised about the risks of infection and necrosis. Alternatives like finasteride, dutasteride, microneedling, oral minoxidil, and scalp massages are suggested.

Hair loss treatments, specifically, discussing the effectiveness and side effects of finasteride, minoxidil, and RU58841 in various microdoses. It also includes an updated graph which provides information on how different doses affect DHT levels, scalp skin and serum androgen levels, as well as hair count.

Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.

A user experienced reduced stress and improved hair appearance after getting a buzzcut while using finasteride, minoxidil, and microneedling. The user feels the haircut and treatments may have improved hair quality and filled in patchy areas.

Pyrilutamide, a new drug being tested to combat hair loss that has been found to perform comparably or better than finasteride and dutasteride in the initial 6 months of treatment with minimal reported side effects.

User noticed scalp showing at 26, started finasteride at 28, and saw hair improvement by 30. Others shared similar experiences and advised trusting personal observations and trying finasteride early to prevent further hair loss.

A 17-year-old is experiencing diffuse thinning, dandruff, body hair shedding, and other symptoms, possibly linked to seborrheic dermatitis or telogen effluvium. They are using ketoconazole shampoo and considering blood tests to check for thyroid issues or deficiencies.

A 37-year-old male stopped using finasteride and minoxidil due to side effects and switched to derma rolling, scalp massaging, and Revita shampoo, resulting in thicker, healthier hair with new growth. Users discuss the effectiveness of mechanical scalp stimulation, with some sharing similar positive experiences and others expressing skepticism.

The user cannot tolerate oral finasteride and is considering topical finasteride, minoxidil, microneedling, and RU58841 as alternative treatments for hair loss. They seek advice on whether these options are worth trying.

A 30-year-old with a family history of receding hairlines is considering starting finasteride due to gradual hairline recession. They are seeking advice on whether to begin treatment or if they are worrying unnecessarily.

The user is using 0.1% dutasteride, 1% minoxidil with 2% procapil and 0.005% caffeine in the morning, and 1% minoxidil with 2% procapil and 0.01% tretinoin at night. They are concerned about the solution vehicle's effectiveness in preventing systemic absorption and ensuring the products stay around the hair follicles.

After 8 months of using topical finasteride, hair miniaturization continues, raising concerns about its effectiveness. Microneedling is suggested as a possible complementary treatment.

A 28-year-old is assessing their hair loss on the Norwood scale, considering adding topical minoxidil and dermastamping to their current regimen of oral finasteride and minoxidil. They feel their hair loss is worsening and seek opinions on their condition.

The conversation discusses concerns about potential side effects, specifically gynecomastia, from taking 1mg of finasteride every other day for hair loss. Bloodwork results were shared, but more information was requested to provide advice.

A 5-year-old male considering using finasteride to prevent receding hairline, with suggestions ranging from topical minoxidil and estrogen treatments to hair transplantation and shaving.

The post discusses speeding up verteporfin trials for hair loss treatment. The original poster, involved in the trials, requests help in crowdsourcing doctor emails to spread awareness and gather more support for the trials.

The user has been using Minoxidil and Spiro for hair loss treatment but reduced the Minoxidil dosage due to side effects, leading to increased hair loss. They are considering adding the Inkey List caffeine stimulating scalp treatment to their routine and are seeking advice on its safety and effectiveness when used with Minoxidil.

The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

A user is starting a hair loss treatment with a 3-in-1 spray containing finasteride, minoxidil, and tretinoin. They are concerned about whether to continue shaving their head and how to determine if hair follicles are dead.

A 31-year-old man from India is starting a hair loss treatment routine using finasteride, minoxidil, ketoconazole shampoo, and supplements for vitamin deficiencies. He is considering switching to oral minoxidil and possibly using Redensyl serum, while also exploring the effectiveness of dutasteride compared to finasteride.

The conversation is about adding dermarolling to a hair loss treatment routine. The user seeks recommendations for dermarollers, stamps, or pens, emphasizing the importance of quality and proper cleaning.

The user is considering switching from finasteride and minoxidil to dutasteride for better hair regrowth results, as they are experiencing thinning and shedding despite current treatments. They have also tried microneedling, Clobetasol, and salicylic acid to manage scalp issues and inflammation.

A user's positive experience with finasteride for hair loss treatment over two months, noticing less visible scalp after haircuts. The user also used a derma roller occasionally but did not use minoxidil.

A 25-year-old noticed thinning hair at the temples and started using finasteride (1mg/day) for two months, along with keto shampoo twice a week and vitamins like vitamin D, biotin, and zinc. They are seeing some results and are hopeful about regaining lost hair.

The user is experiencing scalp irritation after increasing their finasteride and minoxidil dosage with tretinoin and is considering reducing application frequency. They seek advice on managing the irritation.

The user is experiencing one-sided diffuse thinning and has been using finasteride and liquid minoxidil for 4-5 years with minimal results. They are considering whether to save for a hair transplant or address scalp sensitivity and irritation first.

The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

The user is using Finasteride gel and considering adding Redensyl to their routine, along with weekly microneedling, but is hesitant to use Minoxidil due to its initial shedding phase. They seek advice on the safety and ideal routine for combining these treatments.

A 17-year-old is concerned about hair loss and questions his dermatologist's advice against using finasteride due to age. The dermatologist recommended a serum with aloe vera, saw palmetto, biotin, and dexpanthenol, but the user is skeptical and considers using minoxidil instead.

Kintor Pharma completed patient enrollment for a Phase II trial in China for GT20029, a potential new treatment for hair loss. Some believe GT20029 could replace finasteride if effective, while others discuss finasteride's limited efficacy and potential underreported side effects.