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PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

A 22-year-old man experienced significant hair loss after stopping minoxidil and finasteride, causing emotional distress. He resumed these treatments and is considering dutasteride and microneedling to manage his hair loss.

After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.

A user shared their 10-year hair loss journey, detailing treatments including minoxidil (Kirkland and Alopexy 5%), finasteride, and recently starting dutasteride. They experienced varying results, with significant improvement from minoxidil and finasteride, and are currently seeing positive effects from dutasteride without side effects.

The user shared progress on hair loss treatment, starting finasteride in 2018 and adding minoxidil in November 2023, with significant improvement. The user started treatment at age 31.

Some individuals taking finasteride for hair loss report increased libido and frequent masturbation, with no immediate hair regrowth but darker hair appearance. A dermatologist explains that finasteride may raise testosterone levels temporarily, which could lead to increased sex drive in some people.

The user is experiencing worsening hair loss despite using finasteride and is advised to add minoxidil to their treatment. Concerns about side effects and the effectiveness of combining finasteride and minoxidil are discussed.

A 35-year-old started finasteride in 2014 for hair loss and maintained hair density for 7 years, occasionally using ketoconazole shampoo. Switched to dutasteride in 2022 due to increased hair fall, experimented with dosages, and found a combination with tamsulosin effective despite initial adverse reactions.

Finasteride improved hair appearance over seven years with no major side effects. Users discussed finasteride, minoxidil, and supplements like beta carotene and astaxanthin for hair loss treatment.

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

A user experienced hair thinning after inconsistent use of finasteride and minoxidil while living abroad. They are now considering switching to dutasteride, which some believe is more effective, though others caution it may not work better for everyone.

The user is experiencing positive hair growth after 3 months using 0.5mg dutasteride, 2.5mg oral minoxidil, topical minoxidil, dermastamping, and biotin shampoo, with some side effects like reduced libido and palpitations. They plan to continue treatment for a year before considering a hair transplant, as advised by another user who suggests waiting for full results from minoxidil and finasteride.

Significant hair improvement was achieved using 1.25mg finasteride and 5mg oral minoxidil daily, with no side effects. The user increased the minoxidil dosage to 7.5mg after noticing minor thinning and plans to continue the routine.

The user experienced hair thinning after using expired Finasteride for two months and is concerned about its effectiveness. They have resumed using a new box and hope to recover any lost progress.

A user is experiencing renewed hair loss despite using minoxidil and finasteride for two years and is considering options like dutasteride, increasing finasteride dosage, or starting microneedling. Respondents suggest waiting another month before making changes, consulting a dermatologist, and potentially adjusting the treatment regimen.

User experiencing hair loss tried Minoxidil, Finasteride, Microneedling, Ketoconazole shampoo, and Biotin. Others suggest continuing current treatment for 1-2 years before considering Dutasteride and RU58841.

A new hair loss treatment, Pyrilutamide, has been released and is claimed to be a strong anti-androgen, potentially effective when used with finasteride. However, there are mixed opinions on its effectiveness and safety, with some users skeptical and others purchasing it.

The conversation is about a user's positive experience with hair loss treatment using 1.25mg finasteride and 3-4ml minoxidil for nine months, and ketoconazole also helped. The user started noticing hair loss around age 23 or 24.

The post discusses the user's experience with hair loss treatment RU58841, which was tested for quality and found to be 96+% pure. The conversation includes various responses, with some users questioning the safety of the product and others expressing satisfaction with the test results.

The user experienced significant hair regrowth after using 1.25mg finasteride for 7 months, with no side effects, and is considering whether to keep or remove a previous SMP (scalp micropigmentation). They avoided minoxidil due to dandruff and sensitive scalp concerns, and they use a specific dandruff shampoo once a week.

The user successfully regrew hair using Finasteride, Minoxidil, and microneedling, achieving thicker hair and a fuller hairline. They recommend this method over hair transplants, highlighting the importance of patience and consistency.

A 15-year-old is concerned about hair loss, possibly at Norwood 2 or 3, and is using shampoos and conditioners recommended by a trichologist. Suggestions include considering topical minoxidil and consulting a doctor about topical anti-DHT treatments like finasteride or RU58841, but avoiding 5-alpha-reductase inhibitors at this age.

A user experienced significant hair regrowth using finasteride and minoxidil over four years, despite side effects like seborrheic dermatitis, urinary changes, and water retention. They were satisfied with the results and maintained a strong physique.

The user reported significant improvement in hair quality and stability using topical finasteride for two years, without side effects. They later added minoxidil, which may have further enhanced hair quality.

The conversation discusses hair loss treatments, specifically the use of dutasteride, finasteride, and other methods like PRP, laser, and mesotherapy. Despite these treatments, the user is experiencing hair loss, and others suggest consulting a dermatologist, considering alternative treatments, and addressing potential scalp inflammation.

The user experienced hair loss after 21 months of using oral minoxidil and finasteride and is considering switching to dutasteride. Others suggest it might be temporary and recommend staying consistent or trying additional methods like hair loss shampoo, microneedling, or checking vitamin levels.

A 24-year-old male is losing hair despite using dutasteride and oral minoxidil, with no regrowth from April to October 2024. He is considering increasing his dosage and looking for cheaper prescriptions, while others recommend consulting a trichologist or trying different treatments.

A user is experiencing ongoing hair loss despite using 0.5mg dutasteride and 2.5mg oral minoxidil for several years and is seeking advice. Suggestions include ensuring correct diagnosis, checking for other health issues, considering finasteride, trying topical antiandrogens, and consulting a dermatologist.

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.