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      community Will PP405 render Minox and Fin obsolete?

      in Research/Science  26 upvotes 9 months ago
      PP405 might make minoxidil unnecessary, but finasteride or other 5AR inhibitors may still be needed. PP405 is expected to be expensive and not available until at least 2028, with limited information on its effectiveness.

      community The end of minoxidil and fin/dut regime

      in Research/Science  104 upvotes 4 weeks ago
      New hair loss treatments like GT20029 and PP405 could potentially replace minoxidil and finasteride, offering better results with fewer side effects. However, current treatments like finasteride and minoxidil are still effective for many, despite concerns about side effects.

      community The best vehicle/carrier for RU58841

      in Treatment  2 upvotes 2 years ago
      The conversation is about the best vehicle for RU58841, comparing trichosol and Garnier/Vichy Stemoxydine, avoiding propylene glycol (PG) or ethanol due to previous scalp damage. The user is also seeking sources for these products in the EU.

      community is Oleanic acid a DHT blocker ?

      in Treatment  4 upvotes 1 year ago
      A user is experiencing hair thinning and is using a peptide with oleanic acid as a DHT blocker, along with minoxidil, while waiting for topical finasteride. They plan to use a combination of minoxidil, finasteride, dermastamp, ketoconazole, and scalp massages, but are advised to stick to proven treatments like finasteride and minoxidil.

      community DIY NutraKos-style 6–amino-acid mix (recipe + references)

      in Product  1 upvotes 2 months ago
      A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

      community How do I layer multiple treatments?

      in Treatment  2 upvotes 1 year ago
      The user asks about the order and compatibility of using topical minoxidil, stemoxydine, The Ordinary natural moisturizing factors + HA for scalp, RU58841, and Nioxin system 2 leave-in treatment. They seek advice on layering these hair loss treatments.

      community Looks like I’m allergic to propylene glycol..

      in Minoxidil  5 upvotes 3 years ago
      The user is experiencing an allergic reaction to propylene glycol in Kirkland minoxidil and is considering switching to a foam version or a low-PG minoxidil solution. They are also contemplating oral minoxidil but are concerned about its long-term safety.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 2 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Sources for peptides and Dut/Fin

      in Treatment  1 upvotes 1 month ago
      The user is seeking advice on sourcing finasteride, dutasteride, and minoxidil, as their doctors are unwilling to prescribe both finasteride/dutasteride and minoxidil simultaneously. They are also looking for sources of GHK-Cu and RU58841 in the USA, with suggestions including using services like Hims, ro.co, and Musely.

      community We are NOT all the same. This community should check itself.

      in Treatment 4 years ago
      The user claims to have successfully treated hair loss using natural supplements like collagen, L-lysine, zinc, B12, and bamboo shoot extract, without using the "Big 3" treatments (Minoxidil, finasteride, RU58841). The community is skeptical, demanding proof and emphasizing that the "Big 3" are proven effective, while natural remedies are often not.

      community The future of hair loss drugs.

      in Research/Science  32 upvotes 2 months ago
      Clascoterone 5% and PP405 are being discussed as potential future treatments for hair loss, with clascoterone nearing phase three completion and PP405 possibly taking a cosmetic route to market. Current treatments like minoxidil, finasteride, and RU58841 are mentioned as effective in slowing hair loss, but a complete cure remains elusive.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  55 upvotes 3 weeks ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Here’s the rundown on scalp serums from a former cosmetic chemist

      in Research/Science  29 upvotes 2 months ago
      Most scalp serums are ineffective for hair loss, with Nécessaire’s “The Scalp Serum” being the only one showing noticeable results, though it's not worth the cost. For androgenetic alopecia, clinical treatments like minoxidil and finasteride are necessary, while caffeine and capixyl may offer some benefits.

      community White hair seemed to be turn black, re-pigmentation

      in Update  1 upvotes 5 months ago
      The user experienced hair repigmentation and attributes improvements in hair and overall health to a carnivore diet, Boron, and Selenium supplementation. They stopped using finasteride after 20 years, noticed increased testosterone and libido, and observed hair regrowth with RU58841.

      community Is this regrowth. Semi natural approach.

      in Is this regrowth?  5 upvotes 2 years ago
      The conversation discusses a hair loss treatment regimen that includes scalp massage, derma rolling, saw palmetto, rosemary, peppermint oil, pumpkin seed oil, and various supplements like vitamins C and D, multivitamins, biotin, collagen, and fish oil. The user is asking if the treatment has led to hair regrowth.

      community Topical bimatoprost or latanoprost

      in Product  11 upvotes 1 year ago
      OP is considering adding topical bimatoprost or latanoprost to their hair loss treatment, which already includes oral minoxidil, and is seeking reliable sources for these products. Users discuss the effectiveness and sourcing of these treatments, with some using bimatoprost for both hairline and eyelashes, and others planning to use latanoprost mixed with finasteride.

      community Is this the nuclear stack? Wanna go from NW3 to NW1 at the age of 23

      in Treatment  20 upvotes 2 months ago
      A user is considering an extensive hair loss treatment regimen including oral dutasteride, oral minoxidil, topical finasteride, tretinoin, microneedling, keto shampoo, laser comb, and PRP injections. Suggestions include simplifying the routine, possibly increasing minoxidil dosage, and considering alternatives like RU58841, while cautioning against using estrogen due to potential side effects.