Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.
Minoxidil may cause fine lines and dark circles, but effects might be reversible with retinol. Users report mixed experiences, with some noticing skin changes and others not.
The user had more hair at age 39 than at 27 after using dutasteride, oral minoxidil, RU58841, and ketoconazole for over two years. Initially started with finasteride but switched to dutasteride after six months.
User questions credibility of a hair loss "cure" found by a non-expert and warns against wasting money on unproven supplements. Others discuss trying natural extracts and the importance of researching the enzyme 3ADH for potential hair growth benefits.
A new human trial using an FDA-approved treatment for wound healing called Verteporfin, which may potentially be able to reverse scarring and regrow hair in that area. The trial is only lasting one month so far.
The conversation discusses hair loss treatments, specifically using Minoxidil, finasteride, and RU58841. It also mentions the importance of raising vitamin D3 levels.
Promising hair loss treatments in clinical trials include Pyrilutamide, GT20029, CB-03-01, and PP405, with potential market releases between 2027 and 2029. Hair cloning remains experimental and expensive, while existing treatments like finasteride, minoxidil, and microneedling continue to be used.
A 23-year-old has been using minoxidil for 1.6 years, finasteride for 1 year, and ketoconazole shampoo, along with biotin, to treat hair loss. They noticed baby hairs and a fuller hairline but seek further improvement, especially in the temple areas, and are considering adding rosemary oil and a dermastamp.
The conversation is about a person considering participating in a study for Clascoterone, a topical cream for hair loss, and seeking advice on potential side effects. They have mild hair loss and are not currently using other treatments like finasteride.
The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.
A 41-year-old is addressing hair loss by eating better, using a dermaroller, and taking Nutrafol, but many suggest adding finasteride and minoxidil for better results. The conversation includes mixed opinions on Nutrafol's effectiveness, with some recommending pharmaceutical treatments like finasteride and minoxidil for more significant hair regrowth.
Clascoterone 5% topical solution is effective and safe for long-term use in treating male pattern hair loss. Cosmo Pharma aims for EU and US approval, with a potential US release in late 2027 or early 2028.
A person in their 20s is struggling with hair loss, using treatments like minoxidil and finasteride. Suggestions include self-improvement, therapy, hair transplants, and focusing on acceptance and confidence.
A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.
CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.
Hair loss treatments like finasteride, minoxidil, and hair transplants have side effects and limitations. There is hope for future advancements in stem cell therapy and hair follicle regeneration, though skepticism about their effectiveness and timeline persists.
A 38-year-old female is experiencing hair loss despite having almost undetectable DHT levels after using dutasteride. Suggestions include checking for PCOS, thyroid issues, adjusting diet, considering the impact of birth control, and trying treatments like tretinoin, redensyl, retinol, and minoxidil with derma stamping.
The user is taking 1mg Dutasteride, 2.5mg oral Minoxidil, topical Minoxidil, 28mg iron, vitamin D3 + K2, and Selenium daily. They are concerned about their receding hairline despite good hair density and crown.
A 17-year-old is experiencing hair loss despite using 5% topical minoxidil, 0.05% tretinoin, and oral minoxidil, and is considering starting oral finasteride after a dermatologist suggested a hair growth spray with Capixyl, Redensyl, Anagain, and Saw Palmetto. Users advise caution with finasteride at a young age, suggesting starting with topical finasteride and consulting an endocrinologist.
A 23-year-old shares their hair and eyebrow regrowth journey, attributing success to a routine involving Minoxidil, Dutasteride, vitamins, biotin, and fish oil, alongside improved lifestyle habits. They report no side effects from Dutasteride and minor itchiness from Minoxidil, noting significant improvements in appearance and satisfaction with the results.
TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.
The user is experiencing progressive hair thinning despite using finasteride and dutasteride. A biopsy confirmed male pattern baldness, and minoxidil was suggested as an additional treatment.
An 18-year-old experiencing hair loss and seborrheic dermatitis has tried finasteride, dutasteride, and various shampoos without success. They are considering anti-androgens like RU58841 and KX-826 for oil control and dandruff reduction.
A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.
A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.
A woman discovered her long-term hair loss was due to undiagnosed anemia, with ferritin levels as low as 9. After starting iron supplements, she saw significant hair regrowth, especially in previously bald areas, though some spots remain unchanged.
A 30-year-old male successfully stopped hair loss and improved hair density using red light therapy, saw palmetto, vitamins, L-Arginine, fish oil, derma rolling, and specific shampoos, after experiencing negative effects from minoxidil and finasteride. He emphasizes focusing on blood flow and natural remedies, noting significant improvements in hair and beard fullness.
A 19-year-old male using 1 mg finasteride every two days for hair loss reports no side effects and believes maintaining his current hair condition is progress. Some users see no difference in hair regrowth, attributing changes to lighting.
Pelage Pharmaceuticals announced positive Phase 2a trial results for PP405 in hair loss therapy. The conversation discusses the delay in publishing full results and the need for further trials and approvals.