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      community spironolactone pills to topical

      in Research/Science  6 upvotes 11 months ago
      Crushing spironolactone pills and combining them with minoxidil for topical application may be effective for hair loss, with the addition of finasteride suggested. Adding rosemary and peppermint oils can help mask the unpleasant smell.

      community Haunting study is making me considering cycling fin/dut

      in Research/Science  158 upvotes 8 months ago
      Concerns about the long-term effects of dutasteride and finasteride on fertility, with discussions on cycling these medications to mitigate risks. The conversation highlights skepticism about study methodologies and the importance of weighing treatment risks against potential fertility issues.

      community Experience with Strut topicals?

      in Product  3 upvotes 1 year ago
      A user has been using a topical hair loss treatment with finasteride, minoxidil, and tretinoin for 4 years without satisfactory results and is considering switching to a different product due to concerns about effectiveness and company reliability. They are seeking others' experiences with Strut and alternative products before making a change.

      community A better treatment would be a localized 5ar inhibitor that breaks down when it enters blood or leaves hair follicle

      in Chat  1 upvotes 10 months ago
      The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.

      community Anyone hear of Ursolic Acid?

      in Question  3 upvotes 6 years ago
      Ursolic acid, found in apple peels, lemongrass, rosemary, and lavender, may have anti-androgen effects similar to finasteride. It might be beneficial for hair health when used with other treatments like Minoxidil, Finasteride, and RU58841.

      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 3 weeks ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community Applying topicals before bed..

      in Treatment  4 upvotes 3 years ago
      Applying hair loss treatments like minoxidil and finasteride, with concerns about side effects and application timing. Some users experience side effects, while others manage without issues, and there's interest in future treatments like pyrilutamide.

      community Do growth serums actually work or just stop further loss?

      in Chat  1 upvotes 3 months ago
      Hair growth serums, specifically those with minoxidil and finasteride, are discussed as potential treatments for hair loss. The effectiveness of these serums is questioned, with a focus on whether they promote regrowth or merely prevent further loss.

      community currently active protocols, working so far

      in Update 3 years ago
      The conversation is about a person's hair loss treatment routine, which includes Metformin, sleep in darkness, avoiding EMF at night, Nizoral, Dermarolling, Castor oil, and Collagen. They have observed less hair shedding and increased hair volume.

      community Low cortisol it is due the fin

      in Finasteride/Dutasteride  7 upvotes 8 months ago
      The user has been taking 1mg finasteride daily for a year with no improvement in hair loss and reports low cortisol levels, sleep issues, and anxiety changes. The conversation includes discussions on the potential effects of finasteride on cortisol and neurosteroids, with suggestions to consult a doctor and consider other factors.

      community important questions about RU58841

      in Research/Science  3 upvotes 2 years ago
      The user has been using finasteride for hair loss and is considering adding RU58841. They ask about RU58841's effectiveness, potential heart side effects, duration of action, dosage increase over time, transitioning to GT20029, and where to find the liquid form.

      community Complete non responder to everything. Modern Norwood Sisyphus

      in Update  76 upvotes 9 months ago
      The user has been using finasteride for four years and topical minoxidil with microneedling for a year but has not seen significant results in slowing hair loss. They are considering trying dutasteride despite concerns about its intensity, and others suggest trying oral minoxidil or combining treatments for better results.

      community How I treated side effects

       9 upvotes 6 years ago
      The conversation discusses treating side effects of hair loss treatments. Recommendations include lifting heavy weights, reducing body fat, taking ZMA and D3 supplements, improving diet, taking DIM, reducing finasteride dosage, avoiding alcohol, drinking water, getting quality sleep, and not obsessing over side effects.

      community Clascoterone - Why are there so few posts if it’s already on the market?

      in Chat  34 upvotes 2 months ago
      Clascoterone is being discussed for hair loss, but its current acne formulation may not be suitable for scalp use due to potential skin irritation and lower dosage compared to Breezula. Users mention other treatments like finasteride, minoxidil, and pyrilutamide, with some expressing skepticism about clascoterone's effectiveness for hair loss.

      community Topical rapamycin, metformin, a-kg grow hair

      in Research/Science  13 upvotes 5 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community Finasteride and hormonal tests

      in Finasteride/Dutasteride 3 months ago
      A user has been taking finasteride 1mg for 10 years without side effects but is concerned about high estradiol levels affecting weight loss. Another user suggests using estradiol blockers under medical supervision to manage the levels.

      community Does anyone use Fluridil as their anti-androgen of choice?

      in Chat  4 upvotes 2 years ago
      Fluridil, a non-steroidal anti-androgen approved for alopecia in parts of Europe, is noted for its low side effects but is not commonly discussed. The user is inquiring if anyone prefers it over other anti-androgens like Spiro or RU58841.

      community Clascoterone - clearnet vendor

      in Chat  2 upvotes 3 months ago
      The conversation is about finding a clearnet vendor for clascoterone, also known as Winlevi, for hair loss treatment. The user is seeking recommendations via direct message.