Switching from finasteride to a generic dutasteride led to unexpectedly high DHT levels, prompting a switch to a reputed brand and consideration of softgel capsules for better absorption. The user plans to retest DHT levels and may return to finasteride if issues persist.
Topical finasteride affects serumDHT less than oral forms, while dutasteride mesotherapy may impact only the scalp with minimal serumDHT effects. Oral dutasteride once a week is suggested to have few side effects.
The user has been using dutasteride and finasteride but still experiences hair loss and high DHT levels. They plan to try topical finasteride and RU58841 while continuing dutasteride to see if topicals are more effective.
The user lost ground on oral finasteride and plans to switch to topical finasteride/minoxidil and microneedling. They are curious if topical treatments are more effective than oral ones.
Creatine may increase scalp DHT without affecting serumDHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.
The conversation is about identifying ingredients in a scalp serum and their effects on DHT levels. The serum contains various ingredients like Aqua, Biotin, and Oleanolic Acid.
Excessive scalp sebum, worsened by DHT, can lead to inflammation and hair loss, with clascoterone mentioned as a treatment. Diet changes seem ineffective for scalp sebum, and treatments like minoxidil and finasteride are suggested.
The conversation discusses the fluctuation of testosterone levels in men under 40 and the difference between serumDHT and scalp DHT. It also mentions that DHT levels are higher on Dutasteride than on Finasteride, which is unusual.
Dutasteride mesotherapy may stabilize hair loss and improve hair without significantly affecting serumDHT levels, but it can still have systemic effects. Users discuss using topical and oral dutasteride, with some experiencing side effects and considering hair transplants.
A user's progress pictures showing visible hair growth results from taking Finast and Minoxidil, as well as using microneedling, Nizoral, and a multi peptide serum for hair density. The conversation also discussed how DHT is the cause of diffuse thinning.
The user discusses the potential impact of external DHT in sebum on hair loss and plans to wash their hair daily with salicylic acid exfoliation. They believe this might help reduce hair loss despite internal factors.
Dutasteride Mesotherapy shows promising hair growth results without affecting serumDHT levels, but the study's small sample size of six patients limits its reliability. The treatment is expensive and not widely available, with concerns about the lack of standardized procedures and long-term research.
Researching and developing an effective local antagonist to block the androgen receptors for hair loss, as opposed to using DHT synthesis inhibitors that lower serumDHT levels. Several treatments such as CosmeRNA and Pyrilutamide are currently in development or undergoing trials.
Finasteride reduced dandruff and scalp oiliness by lowering DHT, which decreases sebum production. Users also noted improvements with Nizoral and dutasteride.
Dutasteride is often taken daily despite its long half-life because consistent dosing maintains optimal serum levels for effective DHT suppression. Some users report success with less frequent dosing, such as three times a week, but effectiveness can vary based on individual response and professional advice.
Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.
A 33-year-old male with a receding hairline is advised to start with finasteride to block DHT and consider minoxidil for promoting hair growth. Other treatments like copper peptides and serums are deemed less effective, and ketoconazole shampoo is suggested for scalp health.
The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serumDHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.
A 21-year-old is experiencing aggressive hair loss and questions the effectiveness of finasteride after 45 days of use, with high DHT levels. A user advises that scalp DHT, not serumDHT, is important for hair loss assessment, and suggests monitoring hair improvement over time.
The conversation discusses sourcing hair loss treatments from India to reduce costs. The treatments include Morr F Minoxidil + Finasteride solution, Traya Recap Hair Serum, a derma roller, and Man Matters DHT Blocking Shampoo and Conditioner.
The user, 31, shares their hair regrowth progress after one year of using Minoxidil inconsistently, becoming more consistent in the last six months, and adding The Ordinary hair density serum. They wash their hair with Hims shampoo, microneedle monthly, and avoid DHT blockers due to potential side effects.
The user has been treating hair loss for over 11 years with various methods including Minoxidil, Keto shampoos, vitamins, and microneedling, but has avoided Finasteride due to fertility concerns. They have recently added Zix and The Ordinary Serum to their routine and are questioning their high DHT levels despite their efforts.
The conversation discusses whether topical finasteride, dutasteride, or antiandrogens like RU58841 can reduce sebum overproduction as an early indicator of their effectiveness in treating hair loss. It suggests that while hair growth may take months to observe, a decrease in oiliness could be a quicker sign of a product's action.
User discusses tight scalp causing hair loss and suggests treatments like scalp massages, PRP, saw palmetto, and eucapil. They share their experience with saw palmetto and eucapil and consider adding PRP and scalp massages for better results.
A user reports high DHT levels despite taking finasteride and is concerned about inconsistent blood test results. They also take modafinil, vitamin D, and magnesium supplements.
Dutasteride significantly reduces DHT levels, potentially more effectively than finasteride, and is used to treat hair loss. Some users report side effects like reduced libido and mood changes, while others experience hair regrowth and increased testosterone.
Creatine may increase DHT levels, but its impact on hair loss is unclear and not well-studied. Many users report no significant hair loss while using creatine alongside finasteride, though some experience increased shedding.
A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.
The user has low testosterone and DHT levels and is considering taking finasteride for Norwood 2 hair loss with diffuse thinning. They are seeking advice on whether low DHT indicates high sensitivity to DHT in the scalp and opinions on their lab values.