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      community It looks like Pelage are giving hints that PP405 is a game changer

      in Chat  239 upvotes 2 months ago
      PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

      community Does anyone have experience with KY19382?

      in Research/Science  3 upvotes 5 months ago
      KY19382 is discussed as a potential treatment for creating new hair follicles and possibly curing hair loss. The conversation seeks user experiences and sourcing information for KY19382.

      community Sanguisorba Officinalis Root Extract, and other FGF-5 inhibitors?

      in Question  3 upvotes 9 years ago
      The conversation discusses the potential of Sanguisorba Officinalis Root Extract as a treatment for hair loss by inhibiting FGF-5. The user also mentions the product évolis, which is based on this extract but is only available in the US and Australia.

      community Let's talk about Tsuji and Shiseido

       5 upvotes 7 years ago
      The conversation discusses hair loss treatments, focusing on Tsuji's hair cloning and Shiseido's RCH-01, with skepticism about their effectiveness on humans. It compares these to PRP, noting PRP's higher efficacy in studies.

      community Finasteride shed after 11 months

      in General  46 upvotes 11 months ago
      The user is experiencing hair shedding after 11 months of using 1mg finasteride. They are seeking advice on how to address the continued shedding.

      community mbp alopecia areata or vitamin deficiency

      in Chat 1 year ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

      community Those with Success with RU58841: Where do you buy it?

      in Treatment  13 upvotes 3 years ago
      The conversation is about where to buy RU58841 for hair loss treatment and tips for its use, with one user suggesting buying powder from a lab in China to save money and sharing their positive 11-week results.

      community Pyrilutamide KX826 Legit Source???

      in Research/Science  2 upvotes 1 year ago
      Pyrilutamide (KX826) sourcing and pricing, with users discussing the legitimacy and cost of grey market versus official sources. The conversation highlights the high cost of official products and the effectiveness of grey market versions.

      community RU58841 is now on Amazon. Is this legit?

      in Product  14 upvotes 2 years ago
      RU58841, a hair loss treatment, is available on Amazon, but its legitimacy is questioned due to sketchy reviews and lack of lab reports. Some users report seeing results, while others experience negative side effects.

      community Latanoprost Availability – Canada

      in Treatment  2 upvotes 3 years ago
      Latanoprost for hair loss is available in Canada at Ford's Family Pharmacy in New Brunswick, with up to 0.03% concentration, six times stronger than glaucoma medication Xalatan.

      community My scalp punch biopsy results🤔?

      in Female  8 upvotes 3 years ago
      Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

      community Itchy scalp from power shampoo with biotin ?

      in Treatment  3 upvotes 1 year ago
      A user is experiencing an itchy scalp after using a shampoo containing biotin, saw palmetto, and caffeine, and is questioning if it's due to the shampoo or balding. They are seeking feedback on others' experiences with similar shampoos.

      community Excited! Just got prescribed Clascoterone 5%

      in Treatment  25 upvotes 1 month ago
      The user is excited about starting Clascoterone 5% for hair loss, a DHT blocker, and expects better results when combined with Minoxidil. The prescription costs $199 for 30 ml or $353 for 60 ml, and the user plans to cover the cost by driving for Uber.

      community Is Breezula The Real Deal?

      in Question  19 upvotes 7 years ago
      The conversation is about the effectiveness of Breezula for hair loss, with skepticism expressed due to lack of scientific proof and mixed results from those using Breezula and RU58841. Some are waiting for clinical trial results before trying treatments like Breezula and SM04554.

      community can someone help me identify these pls

      in Treatment 7 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community DHT Blocker without Selenium and Zinc??

      in Female  6 upvotes 1 year ago
      A female user is seeking a DHT blocker without Selenium or Zinc due to hair breakage and is currently using Saw Palmetto, Nature's Bounty Hair, Skin and Nails, Pumpkin seed oil, Dermastamp, and Pura D'or products. She has tried Minoxidil without success and is considering Finasteride but prefers natural options first.

      community Shopping receipts are anti-androgenic?

      in Chat  29 upvotes 1 year ago
      The conversation discusses the potential use of thermal paper receipts, which contain estrogen, as a treatment for hair loss. Participants humorously debate its effectiveness compared to established treatments like Minoxidil and finasteride.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.