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      community Pyrilutamide - your experience?

      in Product  12 upvotes 3 years ago
      The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

      community Anyone tried switching from RU to Pyrilutamide (KX-826)

      in Product  7 upvotes 5 months ago
      The conversation discusses switching from RU58841 to pyrilutamide for hair loss treatment, with users generally recommending staying on RU58841 if it is effective. RU58841 is sourced from GeneTherica, which ships worldwide.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community Pyrilutamide Phase 3 on its way

      in Treatment  128 upvotes 4 years ago
      Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

      community I gotta get this off my chest, i gotta split something

      in Satire  9 upvotes 2 years ago
      The conversation is a satirical expression of frustration over hair loss, mentioning treatments like spironolactone, microneedling, and topical applications, with references to various hair loss products and personalities in the community.

      community Shredding for 8+ months after having a great result for 1 year HELP !!

      in Treatment  4 upvotes 10 months ago
      The user experienced hair loss improvement with minoxidil, finasteride, dutasteride, and keto shampoo but began shedding again despite medication changes. Other users suggest sticking to a consistent treatment plan and checking vitamin levels, as deficiencies can contribute to hair loss.

      community Pyrilutamide application questions

      in Treatment  3 upvotes 3 years ago
      Sprocketshead asks if pyrilutamide can be applied with minoxidil, and inquires about its consistency and odor. They want to know if it's more high maintenance than topical minoxidil.

      community Feeling the 2nd, perhaps 1st, Dutasteride shed, might shave, might thug it out.

      in Progress Pictures  67 upvotes 1 year ago
      The user is experiencing increased hair shedding after 6 months of using Dutasteride and oral minoxidil, despite previous regrowth and satisfaction with the results. They are considering shaving their head again and discuss the effectiveness of their treatment routine, which includes Dutasteride, oral minoxidil, and Nizoral, while also addressing concerns about side effects like erectile dysfunction and body composition changes.

      community Handle the itch from Minoxidil?

      in Minoxidil  1 upvotes 2 months ago
      Minoxidil can cause scalp itchiness, often due to propylene glycol, and users suggest alternatives like foam formulations without PG, using moisturizing oils, or reducing application frequency. Some recommend ketoconazole or zinc pyrithione shampoos to help with inflammation and itchiness.

      community How many sheds have you had, and over what period of time?

      in Minoxidil  14 upvotes 4 months ago
      People using finasteride and minoxidil for hair loss experience multiple shedding phases, with some reporting regrowth and improved self-esteem, while others struggle with ongoing hair loss. Despite the challenges, many find the treatments worthwhile, though results vary.

      community Starting my Pyrilutamide + ru58841 journey

      in Treatment  11 upvotes 3 years ago
      An individual's journey to treat their severe hair loss condition using the medications Pyrilutamide and RU58841. They will provide regular updates on their progress.

      community Autoimmune disease and balding

      in Update  12 upvotes 2 years ago
      A user diagnosed with Crohn's disease is concerned it might contribute to balding. They have been using keto shampoo, finasteride, and oral minoxidil, which improved their hair but not significantly.

      community Regression? Has anyone experienced this?

      in Progress Pictures  46 upvotes 1 year ago
      The user is experiencing increased hair shedding and is concerned about regression despite consistent use of finasteride, minoxidil, and other treatments. The consensus is that this is likely a temporary shedding phase, and adjustments to the dermarolling frequency are suggested.

      community Thoughts on scalp/hairline tattoos's ?

      in Chat  15 upvotes 2 months ago
      Scalp tattoos can look good but often appear artificial, especially in sunlight or up close, and require regular maintenance. They may boost confidence if done well, but opinions vary on their effectiveness and natural appearance.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 2 years ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

      community Brutal shed at 5 months

      in Minoxidil  5 upvotes 5 years ago
      User experienced significant hair regrowth with multiple treatments, but then had a brutal shedding period, losing progress. Others questioned the number of treatments used and potential side effects.

      community My endless RU58841 cycle [experience thread)

      in Update  10 upvotes 1 year ago
      The user experienced hair loss and itching after stopping RU58841 and resumed it to stop these symptoms. They also use Dutasteride and question which treatment is effective.

      community [rant] being hairless is ruining all my self esteem

      in Chat  178 upvotes 2 months ago
      Hair loss is causing distress and self-esteem issues, with discussions on treatments like finasteride, minoxidil, and hair transplants. Some suggest topical treatments or lifestyle changes, while others stress the importance of confidence and self-acceptance.

      community 6 Months progress, and some second shed anxiety

      in Progress Pictures  10 upvotes 10 months ago
      The user shared progress pictures of their hair journey, noting good results after initial shedding but experiencing a second, more intense shed. They use topical Minoxidil twice daily, Tretinoin at night, oral finasteride daily, and ketoconazole shampoo weekly.

      community cosmeRNA finally now it's pyrilutamide turn

      in Chat  48 upvotes 3 years ago
      Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.