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      community New possible minoxidil alternative?

      in Minoxidil  5 upvotes 1 year ago
      A potential alternative to Minoxidil for hair loss is discussed, specifically a sugar hydrogel. Users express skepticism about new treatments becoming reality.

      community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

      in Research/Science  128 upvotes 3 years ago
      The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

      community Topical rapamycin, metformin, a-kg grow hair

      in Research/Science  13 upvotes 5 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community Has anyone had success with lipodermal solution?

      in Finasteride/Dutasteride  1 upvotes 9 months ago
      The conversation discusses using a lipodermal solution for hair loss, with concerns about side effects from multiple active ingredients. Users mention experiences with minoxidil, finasteride, and dutasteride, noting side effects like brain fog and sexual issues.

      community Surprise Hair Loss Breakthrough: A Sugar Gel Sparks Robust Regrowth

      in Research/Science  131 upvotes 8 months ago
      A sugar gel is claimed to spark hair regrowth, but users express skepticism, noting that minoxidil and finasteride remain the most effective treatments. Many users joke about frequent "breakthroughs" that work on rats but not humans, and some mention the potential of PP405 as a future treatment.

      community Dermastamp only with carrier/essential oil blend

      in Microneedling  16 upvotes 3 years ago
      A user is documenting their natural approach to treating a receding hairline using a dermastamp, essential oils (rosemary oil at 3% dilution with pumpkin seed oil), a multivitamin with vitamin D, and daily collagen shakes. They acknowledge the common recommendations of minoxidil and finasteride but prefer to test natural methods and share their results.

      community Topical Finasteride - Affordable options

      in Finasteride/Dutasteride  4 upvotes 6 years ago
      The conversation discusses affordable options for topical Finasteride, including products like Morr F, 82F, and Essengen 6 Plus, with concerns about availability and cost. The user is seeking effective and convenient solutions, considering options like compounding pharmacies and homemade solutions.

      community Zix in stemoxydine

      in Treatment  5 upvotes 5 years ago
      User considers making Zix topical solution with ethanol/alcohol for hair loss treatment. Asks if crushing b6 and zinc into stemoxydine is possible.

      community Stacking Fluridil / Topilutamide with other + aqueous topicals?

      in Technology  1 upvotes 1 year ago
      The conversation discusses how to use fluridil/topilutamide with other hair loss treatments like liquid minoxidil and CB-03-01, considering fluridil's hydrophobic nature and potential degradation with water. The user questions the necessity of washing hair only once per week as suggested by the manufacturer.

      community Combine minoxidil, tazarotene, lumigan

      in Treatment  3 upvotes 10 months ago
      Combining minoxidil 5%, tazarotene 0.1% cream, and lumigan for hair loss treatment is discussed. The conversation focuses on the safety and effectiveness of using these treatments together.

      community Has anyone tried latanoprost+microneedle?

      in Microneedling  2 upvotes 2 years ago
      Microneedling combined with latanoprost may convert vellus hairs to transitional or terminal hairs. The user suggests using oral minoxidil to increase vellus hair, then applying a high concentration of latanoprost with microneedling for conversion.

      community Ordered copper peptides - how to apply?

      in Treatment  1 upvotes 1 year ago
      Gizzela is unsure about the dosage and frequency of copper peptides and asks if they can be used with Stemoxydine. They seek advice on applying these treatments together.

      community Recommend me a topical product

      in Product  3 upvotes 6 months ago
      The user is experiencing hair loss and is seeking a topical product without alcohol that doesn't irritate the scalp or make hair brittle. They have previously used minoxidil and finasteride but had negative experiences, and are considering a gel-based product recommended by another user.

      community New & Improved Hair Growth Stack for Maximum Results

      in Treatment  4 upvotes 1 year ago
      A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 3 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community Diluting Melatonin Sublingual Spray

      in Treatment  2 upvotes 2 years ago
      A user wants to dilute a melatonin sublingual spray to 0.0033% for use as a topical hair loss treatment. They ask if distilled water can be used for dilution and how much is needed for stability over months.

      community Trichosol, polyethylene glycol, and DMSO

      in Minoxidil  3 upvotes 2 years ago
      The user experiences irritation from alcohols in minoxidil and is considering alternatives like trichosol mixed with polyethylene glycol or DMSO. They seek advice on the best nonirritating option.

      community OND-1 "Cyclosporine A” New hair loss treatment

      in Research/Science  28 upvotes 1 month ago
      Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

      community VT Reedle Shot for hair growth?

      in Microneedling  1 upvotes 7 months ago
      The VT Reedle Shot, a skincare product using silica spicules, is discussed as a potential at-home alternative to microneedling for hair regrowth. It is suggested that different intensities may aid in hairline regrowth.