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      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  63 upvotes 6 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community Should I stop using minoxidil?

      in Minoxidil  18 upvotes 6 years ago
      A 19-year-old user discusses using finasteride and switching from procapil to minoxidil, experiencing hair shedding and considering stopping minoxidil due to cost and effectiveness concerns. A reply suggests discontinuing minoxidil and continuing with finasteride alone.

      community How do you use rosemary oil and peppermint oil?

      in Question  7 upvotes 6 years ago
      Rosemary oil and peppermint oil may promote hair growth and increase cutaneous blood flow, showing promise as treatments for androgenetic alopecia. Minoxidil 2% is also used for treating hair loss.

      community Setipiprant trial results

      in Update  10 upvotes 7 years ago
      Setipiprant trial for hair loss failed, showing no difference between placebo and treatment. Discussion also noted placebo users reporting side effects.

      community ASATONA AG and "Asatex"

       4 upvotes 7 years ago
      The conversation discusses Melatonin's potential benefits for AGA and a product called "Asatex" by ASATONA AG. The company was uncooperative when contacted for purchase inquiries.

      community Norwood 1 to 3 is normal, and NOT balding

       7 upvotes 7 years ago
      Norwood 1-3 hair loss is considered normal in Russia and not balding. Using finasteride for Norwood 1-3 is seen as unnecessary and risky.

      community Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenetic alopecia and measuring patient satisfaction rate

      in Minoxidil  17 upvotes 8 years ago
      Comparing the effectiveness of minoxidil 5% and adenosine 0.75% for treating male androgenetic alopecia, and measuring patient satisfaction rate; results showed that adenosine is comparable to minoxidil but provides quicker results, however availability of products with adenosine is much less than those with minoxidil.

      community a new supplement just released

       11 upvotes 8 years ago
      A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

      community What I've Learned: A Quality of Life Guide

       81 upvotes 9 years ago
      The post discusses hair loss treatments, specifically using minoxidil, finasteride, nizoral, and sulfur-including shampoo. The author shares personal experiences and tips for application, frequency, and managing side effects, noting significant regrowth with both minoxidil and finasteride.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 2.5 Months on Dutasteride and 5% topical Minoxidil

      in Finasteride/Dutasteride  146 upvotes 1 month ago
      The user experienced increased sex drive and financial cost after 2.5 months on Dutasteride and 5% topical Minoxidil. They advise starting treatment early to prevent hair loss and mention that side effects are minimal, with Dutasteride having a longer-lasting presence in the system compared to Finasteride.

      community What actually helped with my hairfall

      in Treatment 1 month ago
      A user shared their experience with hair loss treatments, finding success with a topical hair serum containing GHK Cu and AHK Cu, which reduced shedding. They avoided hormonal treatments like finasteride and minoxidil, and noted skepticism from others about non-traditional treatments.

      community What are everyone's expectations for PP405?

      in Chat  10 upvotes 1 month ago
      PP405 is expected to be a promising addition to hair loss treatments, potentially working well with existing treatments like finasteride and minoxidil, but not as a standalone solution. Users are hopeful for its effectiveness, especially in combination with other treatments, though expectations vary.

      community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

      in Technology  613 upvotes 1 month ago
      A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

      community 4 Month Progress, 34 M- Minoxidil 5%+ Finasteride .2% liquid + Tretinoin 0.01% liquid - Once a day + Dermaroller once a week. Picture in the comments as well.

      in Is this regrowth?  40 upvotes 1 month ago
      A 34-year-old male shares his 4-month progress using Minoxidil 5%, Finasteride 0.2% liquid, Tretinoin 0.01% liquid, and a dermaroller once a week for hair regrowth, reporting no side effects and noticing baby hairs on the crown. He prefers topical treatments over oral Finasteride and is optimistic about further progress.

      community Early impressions Rootique Dou + Ulo low dose finasteride

      in Technology  2 upvotes 1 month ago
      A user shares their positive experience using the Rootique Dou applicator with 0.005% finasteride, noting it effectively delivers the product without greasiness and helps with hair regrowth without side effects. Another user reports regrowth using low-dose finasteride from ULO, while avoiding tretinoin due to skin irritation.

      community Good shampoo recommendations - improve thickness and health

      in Product  6 upvotes 2 months ago
      The conversation is about finding a good shampoo to improve hair health and thickness, with recommendations including ketoconazole, pura’d’or, Head & Shoulders Dermaxpro, OGX Argan Extra, and OGX apple cider vinegar shampoo. Users discuss experiences with ketoconazole and suggest adding a scalp cleanser with glycolic acid to the routine.