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      community Thoughts on Lactobacillus Reuteri 6475?

      in Treatment  3 upvotes 1 year ago
      Lactobacillus reuteri 6475 is being used by a person who reports healthier hair after one month, despite initial shedding. The discussion includes speculation about its effects on gut bacteria and scalp inflammation.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community thoughts on topical Saw Palmetto oil

      in Treatment  4 upvotes 2 years ago
      The user is considering topical Saw Palmetto or Pumpkin Seed Oil due to sensitivity to finasteride and cost issues. They also use dermastamping for Minoxidil absorption and seek advice on timing to avoid systemic absorption.

      community South Korean Red Light Therapy Study

      in Research/Science  39 upvotes 4 months ago
      Korean scientists developed a red light therapy that reduces a hair loss marker by 92%. Users discussed the benefits and drawbacks of natural sunlight versus red light caps for hair health, with some suggesting supplements for vitamin D.

      community two months on 2-deoxy-d-ribose (2ddr)

      in Progress Pictures  10 upvotes 1 year ago
      The conversation discusses hair regrowth using 2-deoxy-d-ribose (2DDR) combined with minoxidil, with some users noting new hair growth. The original poster has been using minoxidil for 12 years and is considering combining 2DDR with finasteride, despite past side effects.

      community Clascoterone - what we have right now

      in Research/Science  23 upvotes 4 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Topical minoxidil and salicylic acid

      in Minoxidil  6 upvotes 1 year ago
      The user has been using finasteride for 6 months with decent results and recently added topical minoxidil. They are concerned that salicylic acid in their skincare products might reduce minoxidil's effectiveness.

      community Where is GT20029 already? Grrrr

      in Research/Science  20 upvotes 2 years ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community Tretinoin+Minoxidil heavy shedding. (31M)

      in Treatment  10 upvotes 2 years ago
      A person using Minoxidil, Finasteride, Microneedling, and recently added Tretinoin is experiencing heavy shedding and thinning hair. They suspect Tretinoin has made them respond to Minoxidil and are seeking others with similar experiences.

      community 11 month Progress 17-18yo with RU58841*

      in Progress Pictures  49 upvotes 1 year ago
      The user experienced hair regrowth using a combination of Minoxidil, Finasteride, and RU58841, with Minoxidil used initially and the other treatments added later. The user believes the combination of Finasteride and RU58841 contributed to the regrowth, with RU sourced from MVsupplement.

      community Hair loss seborrheic dermatitis

      in Treatment  8 upvotes 5 years ago
      Hair loss from seborrheic dermatitis can be temporary. Treatments discussed include Minoxidil, finasteride, and RU58841, along with collagen and biotin supplements.

      community mbp alopecia areata or vitamin deficiency

      in Chat 2 years ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

      community Am I a Hyper Responder or is this Normal Growth

      in Is this regrowth?  39 upvotes 1 year ago
      The user experienced significant hair regrowth in 5 weeks using Minoxidil, Finasteride, Dutasteride, biotin, collagen, derma stamping, and a mixture of oils, leading others to label them a "hyper responder." Some users advised caution with microneedling frequency to avoid potential scarring.

      community Is anyone else allergic to Minoxidil

      in Minoxidil  5 upvotes 1 year ago
      A user experienced a painful rash from both liquid and foam minoxidil, suggesting an allergy to minoxidil itself. They are seeking others with similar experiences.

      community minoxidil scalp Inflammation, lossing my hair very fast,

      in Minoxidil  4 upvotes 3 years ago
      The user experienced scalp inflammation and rapid hair loss after using minoxidil, despite initial success. Suggestions included switching to minoxidil foam, using oils, trying aspirin, and considering RU58841 for inflammation and hair loss management.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 1 year ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

      community Just FYI, Here are pictures of 6 months results on Clascoterone 5%. Is it remarkable? No. But it seems likely to be FDA approved considering 1% is already available. This is a win, especially if you pair it with other treatments like Finasteride.

      in Research/Science  152 upvotes 6 months ago
      Clascoterone 5% shows potential for hair thickening and darkening, especially when combined with treatments like finasteride. It may be a good alternative for those who experience side effects from other treatments.

      community Zix in stemoxydine

      in Treatment  5 upvotes 5 years ago
      User considers making Zix topical solution with ethanol/alcohol for hair loss treatment. Asks if crushing b6 and zinc into stemoxydine is possible.

      community Has anyone had luck with Redensyl?

      in Minoxidil  6 upvotes 6 years ago
      The user is seeking an alternative to Rogaine (Minoxidil) due to facial puffiness. Another user responded that Redensyl was ineffective for them.

      community 5 month results on natural protocol, i made a post after 3 mont of treatment wich you can find in my profile. I used different massages(detumescence therapy, wooden brush, tom hagerty exercises)vitamins(d3,fish oil, biotin,msm, magnesium) drank green tea and ate pumpkin seeds( reduces dht)

      in Is this regrowth?  152 upvotes 2 years ago
      The user "Zealousideal-Pack340" shared their 5-month results on a natural hair loss treatment protocol, which included massages, vitamins, green tea, and pumpkin seeds. Some users suggested using medications like finasteride and minoxidil for better results, while others criticized the effectiveness of natural remedies. Overall, there was no clear consensus on the progress of the user's hair regrowth.

      community Doubts about my new exosomes treatment

      in Treatment  6 upvotes 11 months ago
      A 22-year-old is frustrated with ongoing hair loss despite using treatments like topical minoxidil, finasteride, microneedling, oral dutasteride, and oral minoxidil. Their dermatologist suggests treating scalp inflammation with oral tretinoin and using exosomes for alopecia.

      community The sTressful Journey - 4 Year Battle

      in Update  8 upvotes 2 years ago
      The user experienced no results for 3.5 years while using finasteride, minoxidil, and microneedling, but saw improvement after increasing Dutasteride to 0.6mg daily. Current routine includes Dutasteride 0.6mg, minoxidil once a day, and supplements like collagen, biotin, and vitamin D.