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      community Melatonin a possible tool to help fight AGA hair loss.

      in Research/Science  53 upvotes 5 years ago
      Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

      community Stop the fear mongering of oral minoxidil its one of the best treatments available in 2020. It does not cause heart lesions or adverse cardiac effects like people claim. I am maintaining with just oral minoxidil with retrograde alopecia and diffuse thinning all over nw3 hairline

      in Minoxidil  73 upvotes 5 years ago
      Oral minoxidil is considered a safe and effective treatment for hair loss at low dosages, with minimal cardiac risks. Users report positive results, though some experience side effects like increased heart rate and skin changes, and consulting a doctor is advised.

      community 9months progress fin/derma pen/minoxidil

      in Progress Pictures  1000 upvotes 5 years ago
      A user's 9 month progress using Finasteride, Derma Pen/Roller and Minoxidil to treat hair loss. Replies in the conversation include advice on topical application of Minoxidil and Dutasteride for regrowth and hair thickness.

      community Injecting stomach fat into the scalp could cure baldness in just six months

      in Update  114 upvotes 7 years ago
      A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

      community What I've Learned: A Quality of Life Guide

       81 upvotes 8 years ago
      The post discusses hair loss treatments, specifically using minoxidil, finasteride, nizoral, and sulfur-including shampoo. The author shares personal experiences and tips for application, frequency, and managing side effects, noting significant regrowth with both minoxidil and finasteride.

      community 1 Year Progress On 0.5mg Finasteride + 5mg Minoxidil

      in Progress Pictures  1317 upvotes 2 years ago
      A user shared a 1-year progress on hair loss treatment using 0.5mg of oral finasteride and 5mg of oral minoxidil, showing significant hair regrowth from almost bald to much thicker hair. Other users discussed their own experiences with these treatments, with some preferring topical applications to avoid side effects.

      community Topical is superior to oral in terms of results (my theory)

      in Finasteride/Dutasteride  61 upvotes 2 years ago
      The conversation discusses the use of topical minoxidil and finasteride for hair loss, with some users combining them with oral treatments. Users share their experiences and opinions on effectiveness, cost, and convenience, with mixed views on whether topical or oral applications are superior.

      community Minoxidil results - Starts July 7

      in Minoxidil  294 upvotes 6 months ago
      The conversation discusses the use of topical minoxidil for hair loss, with the original poster sharing positive results after three months of use without finasteride. Many users suggest adding finasteride to maintain gains, while others share their experiences and concerns about side effects and application methods.

      community Almost 4 months of fin/min… quit waiting!!!

      in Is this regrowth?  462 upvotes 10 months ago
      A user shared their positive experience with hair regrowth using finasteride, minoxidil, dermastamping, and keto shampoo, noting significant improvement in four months without major side effects. They encouraged others to start treatment early and shared tips for application and tracking progress.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 3 years ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community Using essential oils as well as minoxidil?

      in Minoxidil  5 upvotes 8 years ago
      The conversation is about using a blend of coconut oil, peppermint oil, and rosemary oil with minoxidil for hair loss, and whether it's safe to apply this blend after microneedling.

      community Solo use of Pyrilutamide: UPDATE

      in Update  45 upvotes 3 years ago
      A user who has been using Pyrilutamide for 19 days, experiencing some hair thickening in the right temple and crown area but also having ball ache after microneedling; other users offer advice, caution and skepticism as to whether results can be seen in such a short time.

      community What happened to topical dutasteride??

      in Finasteride/Dutasteride  28 upvotes 1 year ago
      Topical dutasteride is considered for hair loss, but concerns about systemic absorption and side effects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite side effects, while others find topical treatments beneficial but challenging.

      community Important reminder for cat owners ⚠️

      in Minoxidil  441 upvotes 9 months ago
      Minoxidil is extremely toxic to cats, even in small amounts, and can be fatal. Switching to oral minoxidil is safer for cat owners, but precautions should still be taken to prevent exposure.

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 4 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community Ultrasound can show you if your hair will ever grow back

      in Research/Science  41 upvotes 1 month ago
      Ultrasound imaging can non-invasively detect active and inactive hair follicles, inflammation, and fibrosis, potentially reducing unnecessary biopsies. It may help assess hair growth potential and diagnose scalp issues, but some users believe in trying treatments regardless of ultrasound results.

      community I am doing an experience with RU58841

      in Treatment 7 months ago
      The conversation discusses a user experimenting with RU58841 for hair regrowth by ingesting it, which others find concerning. There are mentions of potential side effects and comparisons to other treatments like minoxidil, finasteride, and flutamide.

      community Almost 3.5 months on topical fin/min

      in Progress Pictures  254 upvotes 9 months ago
      The user shared progress after 3.5 months using topical finasteride (0.2%) and minoxidil (5%), noting thicker hair despite a receding hairline. They plan to consider a hair transplant in the future and found applying treatments easier on a shaved head.

      community How can you make your own PP405

      in Research/Science  2 upvotes 9 months ago
      People are discussing making their own PP405 for hair loss treatment using JLX069 and DMSO. There is skepticism about the safety and effectiveness of this homemade solution, with some users expressing concerns about potential risks.

      community Has anyone tried Eucapil. It's available in Europe.

      in Product  1 upvotes 11 months ago
      Eucapil, containing fluridil, is used for hair loss but has impractical packaging. Some users find it effective for maintenance, while others suggest alternatives like anageninc with pyrilutamide.