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      community What’s more reliable right now, pyrilutamide or RU?

      in Treatment  15 upvotes 3 years ago
      Treatments for hair loss, with the user considering Pyrilutamide and RU58841 as options. It is noted that although Pyrilutamide has been studied more and is allegedly more effective, there are doubts about its authenticity in the market. KX-826 is suggested as an alternative as it has a stronger effect than RU58841 and there is scientific research on it.

      community 8 months on dut and just keep shedding

      in Finasteride/Dutasteride  4 upvotes 4 months ago
      The user experienced increased shedding and side effects like oily skin and acne after switching from finasteride to dutasteride, despite initially having success with finasteride. They also tried oral spironolactone, which reduced libido but didn't help with hair loss, and are considering returning to finasteride only.

      community 13 month dutasteride update. Still improving.

      in Progress Pictures  34 upvotes 2 years ago
      The user switched from finasteride to dutasteride for hair loss treatment, also using topical minoxidil, micro needling, keto shampoo, and PRP sessions. They've seen improvements, with reduced hair shedding and new hair growth, especially at the hairline.

      community Should i seek further blood tests given my levels?

      in Finasteride  98 upvotes 1 year ago
      The user is experiencing low libido and mood swings after starting a low dose of topical finasteride. They are considering further blood tests to investigate low testosterone levels and other hormonal factors.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  55 upvotes 3 weeks ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community 2 months of RU after 2 years of fin and OM ED

      in Progress Pictures  53 upvotes 2 years ago
      The user was using 1mg finasteride daily and oral minoxidil 2.5mg daily for two years, then added RU58841 to their routine two months ago and is asking for opinions on any changes in hair growth. They provided progress pictures without dermarolling and maintained consistent lighting for comparison.

      community DHEA, the culprit behind DUPA ? Read this!

      in Research/Science  19 upvotes 2 years ago
      High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

      community Pyrilutamide / KX-826 / Koshine — has it been working for you?

      in Treatment  10 upvotes 1 year ago
      Pyrilutamide/KX-826 is being discussed for its effectiveness in hair regrowth, with some users reporting positive results, especially in early hair loss cases. Users have combined it with treatments like Minoxidil, and some experienced initial shedding before seeing regrowth.

      community 7 month on Finesteride 1mg. Regrowth or not?

      in Is this regrowth?  2 upvotes 9 months ago
      The user has been using Finasteride for seven months to address hair loss but hasn't seen noticeable regrowth and is experiencing brittle, thinning hair with scalp issues. They are also using Salisia and Re’equil Salicylic Acid shampoo for potential psoriasis and are seeking advice from others with similar experiences.

      community Ru58841 2% ED 9 month progress

      in Progress Pictures  17 upvotes 3 years ago
      A user shared their 9-month progress using RU58841 at 2% daily for hair regrowth, initially starting at 5% but reducing the dose due to early signs of gynecomastia, which has since mostly resolved. They achieved their goal of regrowing hair at the temples and hairline.

      community Optimal Pyrilutamide (KX-826) Mix and application

      in Research/Science  8 upvotes 3 years ago
      The conversation discusses how to mix pyrilutamide for hair loss treatment, suggesting a mixture of 500mg pyrilutamide with 70% ethanol and 30% propylene glycol, and a potential application dose of 1mL. The user has not personally used pyrilutamide but has researched its preparation and application based on others' experiences.

      community 2 years of dut, 1 year of loss 24m

      in Progress Pictures  520 upvotes 1 month ago
      The user experienced hair regrowth with dutasteride but later lost progress despite using minoxidil foam and dermastamping. Suggestions included reducing dermastamping frequency, conducting blood tests, and considering oral minoxidil or different brands of dutasteride.

      community PG causing irritation when applying RU

      in Research/Science 2 years ago
      The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.

      community Checking in with my post-fin symptoms

      in Finasteride  5 upvotes 9 years ago
      A user reports persistent sexual side effects three months after stopping finasteride, despite a healthy lifestyle and supplements. They express concern over the lack of libido and infrequent erections.

      community I waited long enough. Shedding since September. Starting RU58841

      in Treatment  11 upvotes 4 weeks ago
      The user experienced significant hair shedding after long-term use of finasteride and dutasteride and is now considering trying RU58841 as a last resort. They have checked health factors and suspect stress and poor sleep may contribute to the shedding, but they are determined to try RU58841 to see if it helps with androgenetic alopecia.

      community June-Dec 5.5 month progress? Fin/Min/Pyri

      in Is this regrowth?  2 upvotes 2 years ago
      The user has been treating hair loss since age 17, now 29, using a daily regimen of topical Minoxidil/Finasteride, Pyrilutamide, Minoxidil, and weekly microneedling. They chose a low dose of Finasteride due to past side effects and report that Pyrilutamide has stopped hair shedding and they believe there is some regrowth and increased thickness.

      community Positive Hair Result in Patient using Tirzepatide

      in Research/Science  6 upvotes 1 year ago
      A 57-year-old man with male pattern hair loss and insulin resistance experienced hair regrowth and weight loss after using tirzepatide, without other hair treatments. Dysregulated glucose metabolism is linked to hair loss, with tirzepatide potentially improving hair density by normalizing insulin resistance.
      Help me interpret my bloods

      community Help me interpret my bloods

      in General  65 upvotes 10 months ago
      The user is concerned about high prolactin levels and low testosterone levels after stopping finasteride for three weeks. They are considering resuming finasteride but are worried it might further increase prolactin levels.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.